Short exposure of oesophageal mucosa to bile acids, both in acidic and weakly acidic conditions, can impair mucosal integrity and provoke dilated intercellular spaces

R Farré; H van Malenstein; R De Vos; K Geboes; I Depoortere; P Vanden Berghe; F Fornari; K Blondeau; V Mertens; J Tack; D Sifrim

doi:10.1136/gut.2007.141804

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Oesophagus

Short exposure of oesophageal mucosa to bile acids, both in acidic and weakly acidic conditions, can impair mucosal integrity and provoke dilated intercellular spaces

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	Abstract	Full	Pdf
Jul 2008	47	0	85
Aug 2008	8	0	42
Sep 2008	318	39	105
Oct 2008	367	57	91
Nov 2008	54	48	53
Dec 2008	34	32	34
Jan 2009	6	28	34
Feb 2009	16	16	31
Mar 2009	8	12	11
Apr 2009	9	18	27
May 2009	4	14	10
Jun 2009	6	18	21
Jul 2009	11	12	12
Aug 2009	5	5	6
Sep 2009	9	12	12
Oct 2009	9	13	21
Nov 2009	6	11	8
Dec 2009	7	2	4
Jan 2010	4	10	15
Feb 2010	6	13	8
Mar 2010	7	6	5
Apr 2010	7	8	5
May 2010	11	6	13
Jun 2010	14	4	9
Jul 2010	4	7	11
Aug 2010	13	8	10
Sep 2010	16	6	5
Oct 2010	22	9	6
Nov 2010	5	9	7
Dec 2010	8	8	12
Jan 2011	13	11	8
Feb 2011	18	11	15
Mar 2011	11	4	2
Apr 2011	21	6	9
May 2011	16	4	7
Jun 2011	20	3	6
Jul 2011	19	8	7
Aug 2011	21	4	4
Sep 2011	22	3	4
Oct 2011	20	3	5
Nov 2011	26	5	7
Dec 2011	31	9	8
Jan 2012	23	8	3
Feb 2012	23	3	5
Mar 2012	24	7	5
Apr 2012	27	4	8
May 2012	21	8	5
Jun 2012	19	3	6
Jul 2012	16	8	8
Aug 2012	23	8	9
Sep 2012	22	5	2
Oct 2012	18	4	8
Nov 2012	14	9	7
Dec 2012	19	7	7
Jan 2013	15	2	2
Feb 2013	46	13	5
Mar 2013	27	4	4
Apr 2013	24	5	4
May 2013	24	0	5
Jun 2013	12	4	4
Jul 2013	19	1	3
Aug 2013	10	3	2
Sep 2013	5	3	3
Oct 2013	8	4	4
Nov 2013	10	2	4
Dec 2013	8	6	7
Jan 2014	11	3	2
Feb 2014	17	8	7
Mar 2014	17	3	3
Apr 2014	7	6	6
May 2014	12	3	3
Jun 2014	9	11	6
Jul 2014	14	5	2
Aug 2014	11	2	5
Sep 2014	9	5	6
Oct 2014	12	5	6
Nov 2014	8	10	6
Dec 2014	9	6	6
Jan 2015	14	1	1
Feb 2015	4	6	3
Mar 2015	20	8	7
Apr 2015	11	8	8
May 2015	8	6	4
Jun 2015	17	3	5
Jul 2015	2	2	3
Aug 2015	6	6	6
Sep 2015	37	3	1
Oct 2015	10	2	2
Nov 2015	14	3	4
Dec 2015	12	3	1
Jan 2016	20	5	6
Feb 2016	16	7	8
Mar 2016	6	3	4
Apr 2016	16	4	5
May 2016	16	4	4
Jun 2016	7	2	2
Jul 2016	18	3	4
Aug 2016	12	6	8
Sep 2016	18	6	5
Oct 2016	21	2	3
Nov 2016	12	2	2
Dec 2016	18	3	1
Jan 2017	12	3	3
Feb 2017	8	2	2
Mar 2017	21	2	1
Apr 2017	15	3	1
May 2017	20	1	0
Jun 2017	17	1	0
Jul 2017	48	5	4
Aug 2017	58	8	7
Sep 2017	27	7	5
Oct 2017	50	9	4
Nov 2017	59	4	1
Dec 2017	43	0	1
Jan 2018	61	5	6
Feb 2018	47	3	3
Mar 2018	49	8	5
Apr 2018	50	2	0
May 2018	37	3	3
Jun 2018	46	3	2
Jul 2018	28	2	2
Aug 2018	30	6	10
Sep 2018	26	2	1
Oct 2018	42	2	1
Nov 2018	41	2	2
Dec 2018	42	4	2
Jan 2019	31	5	5
Feb 2019	40	2	2
Mar 2019	47	5	0
Apr 2019	27	3	2
May 2019	15	1	0
Jun 2019	44	3	4
Jul 2019	31	5	6
Aug 2019	30	0	2
Sep 2019	28	0	0
Oct 2019	28	6	2
Nov 2019	61	1	0
Dec 2019	44	2	1
Jan 2020	39	3	3
Feb 2020	38	10	4
Mar 2020	37	5	2
Apr 2020	42	6	2
May 2020	53	2	0
Jun 2020	71	3	1
Jul 2020	57	2	2
Aug 2020	22	0	0
Sep 2020	72	10	5
Oct 2020	39	0	0
Nov 2020	86	5	2
Dec 2020	43	6	2
Jan 2021	62	2	2
Feb 2021	84	4	2
Mar 2021	125	2	1
Apr 2021	31	1	0
May 2021	24	5	9
Jun 2021	6	5	7
Jul 2021	1	1	0
Aug 2021	2	1	4
Sep 2021	3	3	2
Oct 2021	49	1	1
Nov 2021	91	5	4
Dec 2021	258	8	5
Jan 2022	88	5	2
Feb 2022	98	10	6
Mar 2022	96	5	2
Apr 2022	46	2	1
May 2022	56	1	1
Jun 2022	65	3	0
Jul 2022	37	2	2
Aug 2022	115	8	3
Sep 2022	87	11	1
Oct 2022	61	8	0
Nov 2022	49	4	4
Dec 2022	31	1	0
Jan 2023	60	2	1
Feb 2023	85	1	0
Mar 2023	64	0	1
Apr 2023	58	2	1
May 2023	39	1	2
Jun 2023	47	7	9
Jul 2023	76	2	2
Aug 2023	44	2	0
Sep 2023	44	6	4
Oct 2023	57	1	0
Nov 2023	20	6	3
Dec 2023	84	4	1
Jan 2024	200	1	7
Feb 2024	39	6	5
Mar 2024	27	2	2
Total	6618	1101	1280

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