Article Text
PostScript
Letter
Anti-inflammatory capacity of lactobacilli peptidoglycan: mucosal and systemic routes of administration promote similar effects - The Authors' reply
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- 2,4,6-Trinitrobenzene sulphonic acid
- probiotics
- lactobacillus
- inflammatory bowel disease
- immunoregulation
We thank Professor Matuchansky1 for his interest in our recent study.2 The strain specificity of the anti-inflammatory capacity of peptidoglycan (PGN) derived from probiotic lactobacilli was indeed shown using the 2,4,6-trinitrobenzene sulphonic acid colitis model and via the intraperitoneal route. We totally agree, however, that the relevant way of probiotic administration for clinical application is indeed the oral route. Related to this, it might be …
Footnotes
Funding Institut Pasteur of Lille, Association François Aupetit. Academic research support.
Competing interests None.
Provenance and peer review Not commissioned; internally peer reviewed.