Concurrent PEDF deficiency and Kras mutation induce invasive pancreatic cancer and adipose-rich stroma in mice

Paul J Grippo; Philip S Fitchev; David J Bentrem; Laleh G Melstrom; Surabhi Dangi-Garimella; Seth B Krantz; Michael J Heiferman; Chuhan Chung; Kevin Adrian; Mona L Cornwell; Jan B Flesche; Sambasiva M Rao; Mark S Talamonti; Hidayatullah G Munshi; Susan E Crawford

doi:10.1136/gutjnl-2011-300821

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Pancreas

Concurrent PEDF deficiency and Kras mutation induce invasive pancreatic cancer and adipose-rich stroma in mice

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Jan 2012	236	77	64
Feb 2012	92	48	30
Mar 2012	108	39	30
Apr 2012	81	26	20
May 2012	87	35	17
Jun 2012	74	30	22
Jul 2012	52	19	15
Aug 2012	87	12	12
Sep 2012	1070	31	75
Oct 2012	492	45	30
Nov 2012	334	21	30
Dec 2012	257	15	20
Jan 2013	178	13	23
Feb 2013	118	16	23
Mar 2013	102	19	13
Apr 2013	114	19	19
May 2013	58	19	22
Jun 2013	45	12	12
Jul 2013	49	25	9
Aug 2013	61	11	10
Sep 2013	47	9	12
Oct 2013	49	15	15
Nov 2013	31	7	7
Dec 2013	55	5	5
Jan 2014	26	6	6
Feb 2014	31	12	11
Mar 2014	44	25	20
Apr 2014	32	17	10
May 2014	33	10	12
Jun 2014	25	14	11
Jul 2014	43	10	9
Aug 2014	24	10	5
Sep 2014	33	7	7
Oct 2014	12	11	4
Nov 2014	18	3	3
Dec 2014	19	12	7
Jan 2015	19	3	3
Feb 2015	20	6	7
Mar 2015	44	13	13
Apr 2015	19	15	12
May 2015	12	7	4
Jun 2015	13	2	5
Jul 2015	20	9	8
Aug 2015	11	5	5
Sep 2015	21	9	4
Oct 2015	7	2	0
Nov 2015	21	9	6
Dec 2015	23	3	5
Jan 2016	31	4	4
Feb 2016	15	4	1
Mar 2016	22	3	7
Apr 2016	6	5	6
May 2016	13	7	6
Jun 2016	74	5	5
Jul 2016	18	10	2
Aug 2016	26	8	10
Sep 2016	33	6	7
Oct 2016	45	11	11
Nov 2016	21	5	3
Dec 2016	19	2	4
Jan 2017	16	8	3
Feb 2017	31	7	7
Mar 2017	27	10	7
Apr 2017	21	15	13
May 2017	44	11	6
Jun 2017	10	8	6
Jul 2017	27	4	4
Aug 2017	40	2	2
Sep 2017	55	11	8
Oct 2017	69	4	4
Nov 2017	79	12	6
Dec 2017	49	4	2
Jan 2018	75	3	1
Feb 2018	70	8	4
Mar 2018	44	8	5
Apr 2018	60	17	4
May 2018	61	11	3
Jun 2018	43	2	4
Jul 2018	53	2	0
Aug 2018	65	4	3
Sep 2018	47	6	6
Oct 2018	56	10	3
Nov 2018	50	8	6
Dec 2018	67	18	4
Jan 2019	69	8	2
Feb 2019	35	6	3
Mar 2019	43	7	2
Apr 2019	76	9	3
May 2019	80	10	2
Jun 2019	62	11	4
Jul 2019	65	13	4
Aug 2019	55	12	0
Sep 2019	74	14	5
Oct 2019	51	7	4
Nov 2019	41	10	7
Dec 2019	69	13	3
Jan 2020	53	7	3
Feb 2020	54	5	2
Mar 2020	34	4	2
Apr 2020	73	8	6
May 2020	47	9	6
Jun 2020	74	5	1
Jul 2020	52	11	3
Aug 2020	41	9	4
Sep 2020	74	4	4
Oct 2020	33	2	1
Nov 2020	48	6	4
Dec 2020	35	1	1
Jan 2021	61	13	7
Feb 2021	70	6	7
Mar 2021	25	3	4
Apr 2021	108	2	2
May 2021	37	8	6
Jun 2021	3	3	3
Jul 2021	4	2	3
Aug 2021	8	9	2
Sep 2021	7	7	1
Oct 2021	48	6	2
Nov 2021	74	6	2
Dec 2021	77	1	1
Jan 2022	60	7	1
Feb 2022	56	6	3
Mar 2022	96	9	3
Apr 2022	45	5	2
May 2022	79	10	5
Jun 2022	71	6	2
Jul 2022	59	9	2
Aug 2022	73	4	3
Sep 2022	65	1	1
Oct 2022	98	4	2
Nov 2022	72	4	2
Dec 2022	46	1	1
Jan 2023	92	7	3
Feb 2023	59	5	0
Mar 2023	82	4	2
Apr 2023	102	3	4
May 2023	69	3	2
Jun 2023	44	0	2
Jul 2023	64	3	0
Aug 2023	51	3	0
Sep 2023	56	4	0
Oct 2023	43	8	1
Nov 2023	48	1	3
Dec 2023	99	4	1
Jan 2024	115	5	2
Feb 2024	123	12	3
Mar 2024	60	5	1
Total	9716	1441	1056

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