Comparison of the clinical prediction model PREMM1,2,6 and molecular testing for the systematic identification of Lynch syndrome in colorectal cancer

Fay Kastrinos; Ewout W Steyerberg; Judith Balmaña; Rowena Mercado; Steven Gallinger; Robert Haile; Graham Casey; John L Hopper; Loic LeMarchand; Noralane M Lindor; Polly A Newcomb; Stephen N Thibodeau; Sapna Syngal; the Colon Cancer Family Registry

doi:10.1136/gutjnl-2011-301265

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Original article

Comparison of the clinical prediction model PREMM_1,2,6 and molecular testing for the systematic identification of Lynch syndrome in colorectal cancer

Authors

Fay Kastrinos Herbert Irving Comprehensive Cancer Center, Columbia University, Medical Center, New York, New York, USADivision of Digestive and Liver Diseases, Columbia University Medical Center, New York, New York, USA PubMed articles Google scholar articles
Ewout W Steyerberg Department of Public Health, Erasmus Medical Center, Rotterdam, the Netherlands PubMed articles Google scholar articles
Judith Balmaña Department of Medical Oncology, Hospital Vall d'Hebrón, Medical Department of Universitat Autònoma de Barcelona, Barcelona, Spain PubMed articles Google scholar articles
Rowena Mercado Population Sciences Division, Dana-Farber Cancer Institute, Boston, Massachusetts, USA PubMed articles Google scholar articles
Steven Gallinger Dr Zane Cohen Digestive Diseases Clinical Research Centre, Mount Sinai Hospital, University of Toronto, Ontario, CanadaDepartment of Surgery, University of Toronto, Ontario, Canada PubMed articles Google scholar articles
Robert Haile Department of Preventive Medicine, Genetic Epidemiology, USC Keck School of Medicine, Los Angeles, California, USA PubMed articles Google scholar articles
Graham Casey Department of Preventive Medicine, Genetic Epidemiology, USC Keck School of Medicine, Los Angeles, California, USA PubMed articles Google scholar articles
John L Hopper Department of Public Health, University of Melbourne, Carlton, Australia PubMed articles Google scholar articles
Loic LeMarchand Epidemiology Division, University of Hawaii Cancer Center, Honolulu, Hawaii, USA PubMed articles Google scholar articles
Noralane M Lindor Department of Medical Genetics, Mayo Clinic, Rochester, Minnesota, USA PubMed articles Google scholar articles
Polly A Newcomb Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USADepartment of Epidemiology, School of Public Health, University of Washington, Seattle, Washington, USA PubMed articles Google scholar articles
Stephen N Thibodeau Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA PubMed articles Google scholar articles
Sapna Syngal Population Sciences Division, Dana-Farber Cancer Institute, Boston, Massachusetts, USADivision of Gastroenterology, Brigham and Women's Hospital, Boston, Massachusetts, USAHarvard Medical School, Boston, Massachusetts, USA PubMed articles Google scholar articles
the Colon Cancer Family Registry
Google scholar articles

Correspondence to Dr Fay Kastrinos, Division of Liver and Digestive Diseases, Columbia University Medical Center, 630 West 168th Street, New York, NY 10032, USA; fk18{at}columbia.edu

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Citation

Kastrinos F, Steyerberg EW, Balmaña J, et al

Comparison of the clinical prediction model PREMM_1,2,6 and molecular testing for the systematic identification of Lynch syndrome in colorectal cancer

Gut 2013;62:272-279.

Publication history

Revised December 16, 2011
Accepted January 6, 2012
First published February 16, 2012.

Online issue publication

October 26, 2017

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