Hedgehog signalling stimulates precursor cell accumulation and impairs epithelial maturation in the murine oesophagus

Willemijn A van Dop; Sanne L Rosekrans; Anja Uhmann; Viljar Jaks; G Johan A Offerhaus; Marius A van den Bergh Weerman; Maria Kasper; Jarom Heijmans; James C H Hardwick; Hein W Verspaget; Daan W Hommes; Rune Toftgård; Heidi Hahn; Gijs R van den Brink

doi:10.1136/gutjnl-2011-301141

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Oesophagus

Original article

Hedgehog signalling stimulates precursor cell accumulation and impairs epithelial maturation in the murine oesophagus

Authors

Willemijn A van Dop Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, Amsterdam, The NetherlandsDepartment of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands PubMed articles Google scholar articles
Sanne L Rosekrans Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, Amsterdam, The NetherlandsDepartment of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands PubMed articles Google scholar articles
Anja Uhmann Institute of Human Genetics, University Medical Center Göttingen, Göttingen, Germany PubMed articles Google scholar articles
Viljar Jaks Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden PubMed articles Google scholar articles
G Johan A Offerhaus Department of Pathology, University Medical Center Utrecht, Utrecht, The NetherlandsDepartment of Pathology, Academic Medical Center, Amsterdam, The Netherlands PubMed articles Google scholar articles
Marius A van den Bergh Weerman Department of Pathology, Academic Medical Center, Amsterdam, The Netherlands PubMed articles Google scholar articles
Maria Kasper Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden PubMed articles Google scholar articles
Jarom Heijmans Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, Amsterdam, The NetherlandsDepartment of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands PubMed articles Google scholar articles
James C H Hardwick Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands PubMed articles Google scholar articles
Hein W Verspaget Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands PubMed articles Google scholar articles
Daan W Hommes Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The NetherlandsCenter for Inflammatory Bowel Diseases, University of California Los Angeles, Los Angeles, USA PubMed articles Google scholar articles
Rune Toftgård Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden PubMed articles Google scholar articles
Heidi Hahn Institute of Human Genetics, University Medical Center Göttingen, Göttingen, Germany PubMed articles Google scholar articles
Gijs R van den Brink Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, Amsterdam, The NetherlandsDepartment of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands PubMed articles Google scholar articles

Correspondence to Dr Gijs R van den Brink, Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, Amsterdam 1105 AZ, The Netherlands; g.r.vandenbrink{at}amc.nl

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Citation

van Dop WA, Rosekrans SL, Uhmann A, et al

Hedgehog signalling stimulates precursor cell accumulation and impairs epithelial maturation in the murine oesophagus

Gut 2013;62:348-357.

Publication history

Revised February 20, 2012
Accepted February 22, 2012
First published April 13, 2012.

Online issue publication

October 23, 2016

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