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Sun et al1 reported a novel stratification model for classifying patients with colorectal cancer by characterising the gene expression profile of the tumours with wild type and mutant KRAS, BRAF and PIK3CA. The authors claimed that the combined transcription signature of these mutant signal molecules might help clinicians identify patients, whose tumour could have similar transcription signature without any mutation and who …
Contributors IHS and AAO were involved in the discussion and manuscript writing process.
Competing interests None.
Provenance and peer review Not commissioned; internally peer reviewed.