Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants

Jihane Romanos; Anna Rosén; Vinod Kumar; Gosia Trynka; Lude Franke; Agata Szperl; Javier Gutierrez-Achury; Cleo C van Diemen; Roan Kanninga; Soesma A Jankipersadsing; Andrea Steck; Georges Eisenbarth; David A van Heel; Bozena Cukrowska; Valentina Bruno; Maria Cristina Mazzilli; Concepcion Núñez; Jose Ramon Bilbao; M Luisa Mearin; Donatella Barisani; Marian Rewers; Jill M Norris; Anneli Ivarsson; H Marieke Boezen; Edwin Liu; Cisca Wijmenga; PreventCD Group

doi:10.1136/gutjnl-2012-304110

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Coeliac disease

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Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants

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Jihane Romanos Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, The NetherlandsSchool of Medicine, Lebanese American University, Beirut, Lebanon PubMed articles Google scholar articles
Anna Rosén Department of Public Health and Clinical Medicine, Epidemiology and Global Health, Umeå University, Umeå, SwedenDepartment of Medical Biosciences, Medical and Clinical Genetics, Umeå University, Umeå, Sweden PubMed articles Google scholar articles
Vinod Kumar Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands PubMed articles Google scholar articles
Gosia Trynka Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, The NetherlandsDivision of Genetics and Division of Rheumatology, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts, USA PubMed articles Google scholar articles
Lude Franke Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands PubMed articles Google scholar articles
Agata Szperl Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands PubMed articles Google scholar articles
Javier Gutierrez-Achury Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands PubMed articles Google scholar articles
Cleo C van Diemen Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands PubMed articles Google scholar articles
Roan Kanninga Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands PubMed articles Google scholar articles
Soesma A Jankipersadsing Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands PubMed articles Google scholar articles
Andrea Steck Barbara Davis Centre for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado, USA PubMed articles Google scholar articles
Georges Eisenbarth Barbara Davis Centre for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado, USA PubMed articles Google scholar articles
David A van Heel Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, London, UK PubMed articles Google scholar articles
Bozena Cukrowska Department of Pathology, Children's Memorial Health Institute, Warsaw, Poland PubMed articles Google scholar articles
Valentina Bruno European Laboratory for Food-Induced Disease, University of Naples Federico II, Naples, Italy PubMed articles Google scholar articles
Maria Cristina Mazzilli Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy PubMed articles Google scholar articles
Concepcion Núñez Clinical Immunology Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria San Carlos IdISSC, Madrid, Spain PubMed articles Google scholar articles
Jose Ramon Bilbao Immunogenetics Research Laboratory, Hospital de Cruces, Bizkaia, Spain PubMed articles Google scholar articles
M Luisa Mearin Department of Paediatrics, Leiden University Medical Centre, Leiden, The Netherlands PubMed articles Google scholar articles
Donatella Barisani Department of Experimental Medicine, Faculty of Medicine, University of Milano-Bicocca, Monza, Italy PubMed articles Google scholar articles
Marian Rewers Barbara Davis Centre for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado, USA PubMed articles Google scholar articles
Jill M Norris Epidemiology Department, Colorado School of Public Health, Aurora, USA PubMed articles Google scholar articles
Anneli Ivarsson Department of Public Health and Clinical Medicine, Epidemiology and Global Health, Umeå University, Umeå, Sweden PubMed articles Google scholar articles
H Marieke Boezen Department of Epidemiology, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands PubMed articles Google scholar articles
Edwin Liu Barbara Davis Centre for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado, USA PubMed articles Google scholar articles
Cisca Wijmenga Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands PubMed articles Google scholar articles
PreventCD Group
Google scholar articles

Correspondence to Professor Cisca Wijmenga, Department of Genetics, University Medical Centre Groningen, PO Box 30001, Groningen 9700 RB, The Netherlands; c.wijmenga{at}umcg.nl

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Citation

Romanos J, Rosén A, Kumar V, et al

Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants

Gut 2014;63:415-422.

Publication history

Received November 11, 2012
Revised April 18, 2013
Accepted April 23, 2013
First published May 23, 2013.

Online issue publication

April 18, 2016

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This web only file has been produced by the BMJ Publishing Group from an electronic file supplied by the author(s) and has not been edited for content.

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Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/3.0/

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