Canonical Wnt signals combined with suppressed TGFβ/BMP pathways promote renewal of the native human colonic epithelium

Amy Reynolds; Natalia Wharton; Alyson Parris; Esther Mitchell; Anastasia Sobolewski; Christy Kam; Loren Bigwood; Ahmed El Hadi; Andrea Münsterberg; Michael Lewis; Christopher Speakman; William Stebbings; Richard Wharton; Kevin Sargen; Richard Tighe; Crawford Jamieson; James Hernon; Sandeep Kapur; Naohide Oue; Wataru Yasui; Mark R Williams

doi:10.1136/gutjnl-2012-304067

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Canonical Wnt signals combined with suppressed TGFβ/BMP pathways promote renewal of the native human colonic epithelium

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Jul 2013	672	413	265
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Oct 2013	602	111	86
Nov 2013	694	84	48
Dec 2013	541	48	47
Jan 2014	252	129	55
Feb 2014	342	78	119
Mar 2014	1380	146	825
Apr 2014	582	111	1083
May 2014	463	105	128
Jun 2014	298	106	99
Jul 2014	127	66	57
Aug 2014	92	50	68
Sep 2014	77	86	73
Oct 2014	82	48	70
Nov 2014	58	44	64
Dec 2014	103	27	65
Jan 2015	73	57	67
Feb 2015	37	61	68
Mar 2015	74	57	78
Apr 2015	51	41	127
May 2015	26	38	87
Jun 2015	31	41	93
Jul 2015	19	54	74
Aug 2015	35	31	94
Sep 2015	60	49	82
Oct 2015	24	30	45
Nov 2015	40	40	79
Dec 2015	38	38	111
Jan 2016	42	39	82
Feb 2016	42	23	48
Mar 2016	18	16	53
Apr 2016	29	31	65
May 2016	33	23	111
Jun 2016	29	27	79
Jul 2016	49	33	186
Aug 2016	29	44	67
Sep 2016	29	16	67
Oct 2016	26	21	89
Nov 2016	59	24	63
Dec 2016	35	26	76
Jan 2017	77	42	94
Feb 2017	10	19	55
Mar 2017	4	24	64
Apr 2017	5	65	45
May 2017	13	43	35
Jun 2017	19	40	33
Jul 2017	53	46	48
Aug 2017	52	46	54
Sep 2017	60	50	36
Oct 2017	92	66	27
Nov 2017	67	45	61
Dec 2017	61	45	57
Jan 2018	71	55	29
Feb 2018	60	42	65
Mar 2018	73	61	39
Apr 2018	67	55	36
May 2018	68	58	29
Jun 2018	62	49	35
Jul 2018	53	43	28
Aug 2018	25	23	13
Sep 2018	52	44	32
Oct 2018	49	41	48
Nov 2018	52	34	64
Dec 2018	34	22	45
Jan 2019	38	32	63
Feb 2019	36	29	28
Mar 2019	42	24	70
Apr 2019	30	18	48
May 2019	37	34	39
Jun 2019	52	26	74
Jul 2019	32	28	59
Aug 2019	29	29	37
Sep 2019	38	32	56
Oct 2019	41	37	19
Nov 2019	29	18	35
Dec 2019	48	34	66
Jan 2020	29	28	35
Feb 2020	58	29	35
Mar 2020	46	37	40
Apr 2020	35	25	49
May 2020	30	24	15
Jun 2020	60	58	47
Jul 2020	16	16	15
Aug 2020	29	18	13
Sep 2020	47	32	9
Oct 2020	99	65	15
Nov 2020	43	39	22
Dec 2020	59	42	26
Jan 2021	58	50	33
Feb 2021	49	42	37
Mar 2021	55	41	31
Apr 2021	43	33	31
May 2021	45	43	31
Jun 2021	33	33	42
Jul 2021	43	43	44
Aug 2021	33	33	42
Sep 2021	29	28	38
Oct 2021	78	74	54
Nov 2021	60	49	54
Dec 2021	50	54	39
Jan 2022	49	50	37
Feb 2022	40	34	46
Mar 2022	58	53	48
Apr 2022	42	38	16
May 2022	70	59	36
Jun 2022	96	96	41
Jul 2022	56	45	25
Aug 2022	65	55	26
Sep 2022	74	63	64
Oct 2022	70	62	48
Nov 2022	116	81	56
Dec 2022	69	67	34
Jan 2023	47	46	43
Feb 2023	38	35	26
Mar 2023	74	69	23
Apr 2023	30	18	26
May 2023	47	32	40
Jun 2023	37	32	17
Jul 2023	57	45	35
Aug 2023	68	55	59
Sep 2023	101	99	38
Oct 2023	122	113	30
Nov 2023	87	78	28
Dec 2023	115	110	29
Jan 2024	49	50	29
Feb 2024	70	62	18
Mar 2024	69	63	25
Total	13406	6671	8682

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