Defective monocyte oxidative burst predicts infection in alcoholic hepatitis and is associated with reduced expression of NADPH oxidase

Nikhil Vergis; Wafa Khamri; Kylie Beale; Fouzia Sadiq; Mina O Aletrari; Celia Moore; Stephen R Atkinson; Christine Bernsmeier; Lucia A Possamai; Gemma Petts; Jennifer M Ryan; Robin D Abeles; Sarah James; Matthew Foxton; Brian Hogan; Graham R Foster; Alastair J O'Brien; Yun Ma; Debbie L Shawcross; Julia A Wendon; Charalambos G Antoniades; Mark R Thursz

doi:10.1136/gutjnl-2015-310378

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Hepatology

Original article

Defective monocyte oxidative burst predicts infection in alcoholic hepatitis and is associated with reduced expression of NADPH oxidase

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Nikhil Vergis Department of Hepatology and Gastroenterology, Imperial College, London, UK PubMed articles Google scholar articles
Wafa Khamri Department of Hepatology and Gastroenterology, Imperial College, London, UK PubMed articles Google scholar articles
Kylie Beale Department of Hepatology and Gastroenterology, Imperial College, London, UK PubMed articles Google scholar articles
Fouzia Sadiq Department of Hepatology and Gastroenterology, Imperial College, London, UK PubMed articles Google scholar articles
Mina O Aletrari Department of Hepatology and Gastroenterology, Imperial College, London, UK PubMed articles Google scholar articles
Celia Moore Department of Hepatology and Gastroenterology, Imperial College, London, UK PubMed articles Google scholar articles
Stephen R Atkinson Department of Hepatology and Gastroenterology, Imperial College, London, UK PubMed articles Google scholar articles
Christine Bernsmeier Department of Hepatology, King's College Hospital, Institute of Liver Studies, London, UK PubMed articles Google scholar articles
Lucia A Possamai Department of Hepatology and Gastroenterology, Imperial College, London, UK PubMed articles Google scholar articles
Gemma Petts Department of Hepatology and Gastroenterology, Imperial College, London, UK PubMed articles Google scholar articles
Jennifer M Ryan Department of Hepatology, King's College Hospital, Institute of Liver Studies, London, UK PubMed articles Google scholar articles
Robin D Abeles Department of Hepatology, King's College Hospital, Institute of Liver Studies, London, UK PubMed articles Google scholar articles
Sarah James Department of Hepatology, University College, London, UK PubMed articles Google scholar articles
Matthew Foxton Chelsea and Westminster Hospital, London, UK PubMed articles Google scholar articles
Brian Hogan Department of Hepatology, Royal Free Hospital, London, UK PubMed articles Google scholar articles
Graham R Foster Department of Gastroenterology, Royal London Hospital, London, UK PubMed articles Google scholar articles
Alastair J O'Brien Department of Hepatology, University College, London, UK PubMed articles Google scholar articles
Yun Ma Department of Hepatology, King's College Hospital, Institute of Liver Studies, London, UK PubMed articles Google scholar articles
Debbie L Shawcross Department of Hepatology, King's College Hospital, Institute of Liver Studies, London, UK PubMed articles Google scholar articles
Julia A Wendon Department of Hepatology, King's College Hospital, Institute of Liver Studies, London, UK PubMed articles Google scholar articles
Charalambos G Antoniades Department of Hepatology and Gastroenterology, Imperial College, London, UK PubMed articles Google scholar articles
Mark R Thursz Department of Hepatology and Gastroenterology, Imperial College, London, UK PubMed articles Google scholar articles

Correspondence to Dr Nikhil Vergis, Department of Hepatology and Gastroenterology, Imperial College Faculty of Medicine, 10th Floor QEQM Building, St Mary's Hospital, London W2 1NY, UK; n.vergis{at}imperial.ac.uk

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Vergis N, Khamri W, Beale K, et al

Defective monocyte oxidative burst predicts infection in alcoholic hepatitis and is associated with reduced expression of NADPH oxidase

Gut 2017;66:519-529.

Publication history

Received July 17, 2015
Revised October 7, 2015
Accepted October 25, 2015
First published February 9, 2016.

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December 13, 2018

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