Footnotes

• Contributors JS and SRL designed and conceived this manuscript. All authors were involved in the analysis and interpretation of data. JS wrote the initial version of the manuscript. All authors provided critical revisions of the manuscript and approved of its final submission.

• Funding This work was partly supported by the National Health and Medical Research Council (NHMRC) of Australia; SRL is an NHMRC Practitioner Fellow.

• Competing interests JS receives fees for travel and expenses as a member of the Merck KGaA Stem Cell Research Oversight Committee and Bioethics Advisory Panel; receives fees for travel and expenses as a member of the Quintiles Ethics Advisory Panel and received fees from Novartis for his role as a consultant on bioethics issues. PR received research funding from Gilead Sciences. FZ received consulting fees from Roche, Gilead Sciences, Janssen, Arbutus, Contravir; and research grants from Roche, Gilead Sciences, Janssen, Sanofi and Assembly Bioscience. YY has received travel grants, honoraria for presentations at workshops and consultancy honoraria from AbbVie, Bristol-Myers Squibb, Gilead Sciences, Merck, Johnson & Johnson and ViiV Healthcare. HLAJ received grants from AbbVie, Bristol-Myers Squibb, Gilead Sciences, Innogenetics, Janssen, Medimmune, Merck, Novartis and Roche; and he is a consultant for AbbVie, Benitec, Bristol-Myers Squibb, Gilead Sciences, GSK, Janssen, Medimmune, Merck, Novartis, Roche and Arbutus. SGL is on advisory boards for Abbott, Gilead Sciences, Novartis, Merck Sharpe and Dohme, Bristol-Myers Squibb and AbbVie; he is on speakers' bureaus for Abbott, Bristol-Myers Squibb. Novartis, Roche, Gilead Sciences, AbbVie and receives educational/research funding from Abbott, Bristol-Myers Squibb, Merck Sharpe and Dohme, Gilead Sciences. SRL's institution has received funding from the National Health and Medical Research Council of Australia, National Institutes for Health, American Foundation for AIDS Research; Merck, ViiV Healthcare, Gilead Sciences and Tetralogic for investigator initiated research and Merck, ViiV Healthcare and Gilead Sciences for educational activities.

• Provenance and peer review Not commissioned; externally peer reviewed.