Identification of distinct mutational patterns and new driver genes in oesophageal squamous cell carcinomas and adenocarcinomas

De-Chen Lin; Huy Q Dinh; Jian-Jun Xie; Anand Mayakonda; Tiago Chedraoui Silva; Yan-Yi Jiang; Ling-Wen Ding; Jian-Zhong He; Xiu-E Xu; Jia-Jie Hao; Ming-Rong Wang; Chunquan Li; Li-Yan Xu; En-Min Li; Benjamin P Berman; H Phillip Koeffler

doi:10.1136/gutjnl-2017-314607

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Oesophagus

Original article

Identification of distinct mutational patterns and new driver genes in oesophageal squamous cell carcinomas and adenocarcinomas

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De-Chen Lin Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA PubMed articles Google scholar articles
Huy Q Dinh Center for Bioinformatics and Functional Genomics, Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA PubMed articles Google scholar articles
Jian-Jun Xie Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA Department of Biochemistry and Molecular Biology, Medical College of Shantou University, Shantou, China PubMed articles Google scholar articles
Anand Mayakonda Cancer Science Institute of Singapore, National University of Singapore, Singapore PubMed articles Google scholar articles
Tiago Chedraoui Silva Center for Bioinformatics and Functional Genomics, Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA PubMed articles Google scholar articles
Yan-Yi Jiang Cancer Science Institute of Singapore, National University of Singapore, Singapore PubMed articles Google scholar articles
Ling-Wen Ding Cancer Science Institute of Singapore, National University of Singapore, Singapore PubMed articles Google scholar articles
Jian-Zhong He Department of Biochemistry and Molecular Biology, Medical College of Shantou University, Shantou, China PubMed articles Google scholar articles
Xiu-E Xu Department of Biochemistry and Molecular Biology, Medical College of Shantou University, Shantou, China PubMed articles Google scholar articles
Jia-Jie Hao State Key Laboratory of Molecular Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China PubMed articles Google scholar articles
Ming-Rong Wang State Key Laboratory of Molecular Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China PubMed articles Google scholar articles
Chunquan Li Department of Biochemistry and Molecular Biology, Medical College of Shantou University, Shantou, China School of Medical Informatics, Daqing Campus, Harbin Medical University, Daqing, China PubMed articles Google scholar articles
Li-Yan Xu Department of Biochemistry and Molecular Biology, Medical College of Shantou University, Shantou, China PubMed articles Google scholar articles
En-Min Li Department of Biochemistry and Molecular Biology, Medical College of Shantou University, Shantou, China PubMed articles Google scholar articles
Benjamin P Berman Center for Bioinformatics and Functional Genomics, Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA PubMed articles Google scholar articles
H Phillip Koeffler Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA Cancer Science Institute of Singapore, National University of Singapore, Singapore National University Cancer Institute, National University Hospital Singapore, Singapore PubMed articles Google scholar articles

Correspondence to Dr De-Chen Lin and Dr Benjamin P Berman, Cedars-Sinai Medical Center, 8700 Beverly Blvd, Los Angeles, CA 90048, USA; dchlin11{at}gmail.com, Benjamin.Berman{at}cshs.org and Dr Jian-Jun Xie and Dr En-Min Li, Medical College of Shantou University, No.22, Xinling road, Shantou, Guangdong province, 515041, China; g_jjxie{at}stu.edu.cn, nmli{at}stu.edu.cn

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Lin D, Dinh HQ, Xie J, et al

Identification of distinct mutational patterns and new driver genes in oesophageal squamous cell carcinomas and adenocarcinomas

Gut 2018;67:1769-1779.

Publication history

Received June 2, 2017
Revised July 10, 2017
Accepted July 13, 2017
First published August 31, 2017.

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December 05, 2018

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© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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