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Contributors All the authors have contributed to the writing of the article.
Funding (Singapore Translational Research (STaR) Investigator Award (NMRC/STaR/013/2012).
Competing interests AB declares the following relationship with commercial entities developing therapeutics for HBV treatment. He collaborates and receives research support from Gilead Sciences to test the effect of HBV antigens on immune cell function. He acted as a consultant and served on the advisory boards of Gilead Sciences, MedImmune, Jansseen-Cilag, IONIS, Abivax, HUMABS BioMed. AB is also a cofounder of LION TCR pte. ltd. a biotech company developing T cell receptors for treatment of virus-related cancers and chronic viral diseases.
Provenance and peer review Commissioned; internally peer reviewed.