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Response to: ‘Circulating microbiome in blood of different circulatory compartments’ by Schierwagen et al
  1. Bastian Volker Helmut Hornung1,
  2. Romy Danielle Zwittink1,
  3. Quinten Raymond Ducarmon1,
  4. Ed J Kuijper1,2
  1. 1 Center for Microbiome Analyses and Therapeutics, Department of Experimental Bacteriology, Leiden University Medical Center, Leiden, the Netherlands
  2. 2 Netherlands Donor Feces Bank, Leiden University Medical Center, Leiden, the Netherlands
  1. Correspondence to Dr Bastian Volker Helmut Hornung, Center for Microbiome Analyses and Therapeutics, Department of Experimental Bacteriology, Leiden University Medical Center, Leiden 2312KT, The Netherlands; bastian.hornung{at}gmx.de

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We read with interest the article by Schierwagen et al,1 who reported on their findings regarding the blood microbiome. Since our research group is working in a hospital setting, recently, we have also considered investigating the blood microbiome using collected blood samples that are potentially available. However, based on recent literature,2 3 we considered the presence of a blood microbiome very unlikely and did not further venture in this direction. We were therefore extremely excited to read this work, but the results quickly raised concerns in our research group. In another area of microbiota research, we recently …

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