Article Text

Download PDFPDF

Letter
Response to the recently published guidelines on lower gastrointestinal bleeding
  1. Samuel Snelling1,
  2. Rania Ghaffar2,
  3. Stephen Thomas Ward1
  1. 1Department of Colorectal Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
  2. 2Department of Radiology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
  1. Correspondence to Stephen Thomas Ward, Department of Colorectal Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2GW, UK; drsteveward{at}yahoo.com

Statistics from Altmetric.com

In response to the recently published national guideline on lower GI bleeding written by Oakland et al,1 we have audited our practice at the Queen Elizabeth Hospital, Birmingham (QEHB). We were most interested by the general recommendation for CT angiography and for the use of ‘Shock Index’ to select patients for CT angiography, with the aim to identify the source of bleeding.

When retrospectively analysing 4 years of admissions (905) for lower GI bleeding, we found that 74 patients underwent CT angiography, with a total of 91 scans. This 8% rate is higher than the national 5.9%.1

Our most interesting finding was the identification of bleeding points on these studies. Only 6.6% of CT angiograms performed at QEHB yielded a positive ‘blush’ or identification of bleeding point. The figure quoted in the national audit is 49.7%.2 We are conducting further investigations to explain the stark difference between our figures and those from around the country. Part of the explanation is ease of access to CT imaging leading to overuse. Without any formal clinical scoring to assess the likelihood of a positive result, there has been no guidance to help clinicians decide who should undergo CT angiography.

The shock index is a measure used for prediction of critical bleeding in trauma, with some studies applying this to acute GI haemorrhage.3 4 However, the majority of patients presenting with lower GI bleeding are over the age of 70 nationally2 and this is reflected in our patient group (median age: 71 years). The shock index agreeably is an easy and quick score to calculate but questions have been previously posed about its use in an ageing population in relation to trauma. These same questions should be posed to its use in GI haemorrhage. Certainly our initial data have shown that half of our positive CT angiograms were for patients presenting below the cut-off of 1. We hope to perform further analysis in this patient group to create an evidence-based pre-test likelihood score for CT angiography.

Furthermore, Oakland et al’s proposed algorithm does not incorporate the use of repeat CT angiography; there is also no discussion of this in the national guideline. Over our 4-year audit period at QEHB, 11 repeat CT angiograms were performed on patients whose previous imaging was negative. No repeat scan positively identified a bleeding point, which would highlight the need to move to other investigations (such as endoscopy) in order to identify clinically significant bleeding.

In summary, our local audit assessing the positive predictive value of CT angiography in patients presenting with lower GI bleeding is significantly at odds with the results from national data. These data have been used to inform the recently published national guideline. We feel that further research is required to establish the pre-test likelihood of positive CT angiography and to determine whether early endoscopy may be a more appropriate modality of investigation.

References

View Abstract

Footnotes

  • Contributors All authors contributed equally to the construction of the text and all authors had the opportunity to view the final text prior to submission.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Not commissioned; internally peer reviewed.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.