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We read with interest the work by Cai et al 1 presenting a precise and cost-effective initial mass-prescreening tool for improving the detection of gastric cancer (GC), including early GC. However, we have several comments on the design and results of this study, hoping to improve the transferability and cost-effectiveness of this prescreening tool to other cohorts.
The first point is about the strategy of handling missing data. This study prevented all participants with any missing data from the analysis without reporting the percentage of those participants in the total cohort, which …
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