Article Text

Download PDFPDF
Curious case of gut dysmotility
  1. Phey Shen Lee1,
  2. Laura Jopson1,
  3. Stephanie J Needham2,
  4. Christopher G Mountford1,
  5. Nick P Thompson1
  1. 1Gastroenterology, Freeman Hospital, Newcastle upon Tyne, UK
  2. 2Cellular Pathology, Royal Victoria Infirmary, Newcastle upon Tyne, UK
  1. Correspondence to Dr Phey Shen Lee, Gastroenterology, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UK; pheyshen.lee{at}nhs.net

Statistics from Altmetric.com

A previously fit 78-year-old man presented with a 2-month history of dysphagia, epigastric pain, bloating, intermittent vomiting and 1½ stone weight loss. There was no history of new medications or recent travel abroad. Oesophagogastroduodenoscopy (OGD) showed a ‘cup and spill’ stomach with mild gastritis. Oesophageal biopsies were normal. CT scan of abdomen/pelvis showed extensive small bowel dilatation to the caecum but no transition point (figure 1A). Exploratory laparotomy revealed dilated small bowel loops without mechanical obstruction. Initial duodenal biopsies showed non-specific flattened villi with thickening and eosinophilia of submucosal vessels. Autoimmune screen including tissue transglutaminase and anti-neuronal antibodies were negative. The patient had normal renal and cardiac function.

Figure 1

(A) CT showing dilated, fluid-filled loops of small …

View Full Text

Footnotes

  • Contributors PSL, LJ and NPT wrote the manuscript. SJN provided the histology images, description of the key features and expert advice. All authors critically appraised and approved the final manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.