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Hepatology
Original research
TGF-β2 silencing to target biliary-derived liver diseases

Authors

  • Anne Dropmann Molecular Hepatology-Alcohol Associated Diseases, Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany PubMed articlesGoogle scholar articles
  • Steven Dooley Molecular Hepatology-Alcohol Associated Diseases, Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany PubMed articlesGoogle scholar articles
  • Bedair Dewidar Molecular Hepatology-Alcohol Associated Diseases, Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany Department of Pharmacology and Toxicology, Faculty of Pharmacy, Tanta University, Tanta, Egypt PubMed articlesGoogle scholar articles
  • Seddik Hammad Molecular Hepatology-Alcohol Associated Diseases, Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, South Valley University, Qena, Egypt PubMed articlesGoogle scholar articles
  • Tatjana Dediulia Molecular Hepatology-Alcohol Associated Diseases, Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany PubMed articlesGoogle scholar articles
  • Julia Werle Molecular Hepatology-Alcohol Associated Diseases, Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany PubMed articlesGoogle scholar articles
  • Vanessa Hartwig Molecular Hepatology-Alcohol Associated Diseases, Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany PubMed articlesGoogle scholar articles
  • Shahrouz Ghafoory Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Heidelberg, Germany PubMed articlesGoogle scholar articles
  • Stefan Woelfl Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Heidelberg, Germany PubMed articlesGoogle scholar articles
  • Hanna Korhonen Isarna Therapeutics GmbH, Munchen, Germany PubMed articlesGoogle scholar articles
  • Michel Janicot Isarna Therapeutics GmbH, Munchen, Germany PubMed articlesGoogle scholar articles
  • Katja Wosikowski Isarna Therapeutics GmbH, Munchen, Germany PubMed articlesGoogle scholar articles
  • Timo Itzel Hepatology and Clinical Bioinformatics, Department of Medicine II, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany PubMed articlesGoogle scholar articles
  • Andreas Teufel Hepatology and Clinical Bioinformatics, Department of Medicine II, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany PubMed articlesGoogle scholar articles
  • Detlef Schuppan Research Center for Immunotherapy, University Medical Center, Johannes Gutenberg University, Mainz, Germany Institute of Translational Immunology, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Ana Stojanovic Department of Immunobiochemistry, Centre for Biomedicine and Medical Technology (CBTM) and European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany PubMed articlesGoogle scholar articles
  • Adelheid Cerwenka Department of Immunobiochemistry, Centre for Biomedicine and Medical Technology (CBTM) and European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany PubMed articlesGoogle scholar articles
  • Stefanie Nittka Institute for Clinical Chemistry, Medical Faculty Mannheim of the University of Heidelberg, University Hospital Mannheim, Mannheim, Germany PubMed articlesGoogle scholar articles
  • Albrecht Piiper Medizinische Klinik 1, Klinikum der Goethe-Universität, Frankfurt am Main, Germany PubMed articlesGoogle scholar articles
  • Timo Gaiser Institute of Pathology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany PubMed articlesGoogle scholar articles
  • Naiara Beraza Gut Microbes and Health Institute Strategic Programme, Quadram Institute, Norwich, UK CIC bioGUNE, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Derio, Spain PubMed articlesGoogle scholar articles
  • Malgorzata Milkiewicz Department of Medical Biology, Pomeranian Medical University, Szczecin, Poland PubMed articlesGoogle scholar articles
  • Piotr Milkiewicz Liver and Internal Medicine Unit, Department of General, Transplant and Liver Surgery, Medical University of Warsaw, Warsaw, Poland PubMed articlesGoogle scholar articles
  • John G Brain NIHR Applied Immunobiology and Transplant Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK PubMed articlesGoogle scholar articles
  • David E J Jones NIHR Applied Immunobiology and Transplant Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK PubMed articlesGoogle scholar articles
  • Thomas S Weiss Department of Pediatrics and Juvenile Medicine, Center for Liver Cell Research, University of Regensburg Hospital, Regensburg, Germany PubMed articlesGoogle scholar articles
  • Ulrich M Zanger Department of Molecular and Cell Biology, Dr Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart, Germany Eberhard-Karls-University Tübingen, Tübingen, Germany PubMed articlesGoogle scholar articles
  • Matthias Ebert Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany PubMed articlesGoogle scholar articles
  • Nadja M Meindl-Beinker Molecular Hepatology-Alcohol Associated Diseases, Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany PubMed articlesGoogle scholar articles
  1. Correspondence to Steven Dooley, Department of Medicine II, Section Molecular Hepatology, Medical Faculty Mannheim, University of Heidelberg, Mannheim 68167, Germany; steven.dooley{at}medma.uni-heidelberg.de; Nadja M Meindl-Beinker; Nadja.Meindl-Beinker{at}medma.uni-heidelberg.de
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Citation

Dropmann A, Dooley S, Dewidar B, et al
TGF-β2 silencing to target biliary-derived liver diseases
Gut 2020;69:1677-1690.

Publication history

  • Received May 15, 2019
  • Revised December 16, 2019
  • Accepted December 17, 2019
  • First published January 28, 2020.
Online issue publication 
February 12, 2021

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.