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Original research
LPIAT1/MBOAT7 depletion increases triglyceride synthesis fueled by high phosphatidylinositol turnover

Authors

  • Yuki Tanaka Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan PubMed articlesGoogle scholar articles
  • Yuta Shimanaka Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan PubMed articlesGoogle scholar articles
  • Andrea Caddeo Department of Molecular and Clinical Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden PubMed articlesGoogle scholar articles
  • Takuya Kubo Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan PubMed articlesGoogle scholar articles
  • Yanli Mao Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan PubMed articlesGoogle scholar articles
  • Tetsuya Kubota Division of Diabetes and Metabolism, The Institute for Adult Diseases, Asahi Life Foundation, Tokyo, Japan PubMed articlesGoogle scholar articles
  • Naoto Kubota Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, JapanDepartment of Clinical Nutrition Therapy, The University of Tokyo Hospital, The University of Tokyo, Tokyo, Japan PubMed articlesGoogle scholar articles
  • Toshimasa Yamauchi Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan PubMed articlesGoogle scholar articles
  • Rosellina Margherita Mancina Department of Molecular and Clinical Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden PubMed articlesGoogle scholar articles
  • Guido Baselli Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milano, ItalyTranslational Medicine, Department of Transfusion Medicine and Hematology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy PubMed articlesGoogle scholar articles
  • Panu Luukkonen Department of Medicine, University of Helsinki and Helsinki University Central Hospital, Helsinki, FinlandMinerva Foundation Institute for Medical Research, Helsinki, FinlandDepartment of Internal Medicine, Yale University, New Haven, CT, USA, Yale University, New Haven, Connecticut, USA PubMed articlesGoogle scholar articles
  • Jussi Pihlajamäki Department of Clinical Nutrition, Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, FinlandClinical Nutrition and Obesity Center, Kuopio University Hospital, Kuopio, Finland PubMed articlesGoogle scholar articles
  • Hannele Yki-Järvinen Department of Medicine, University of Helsinki and Helsinki University Central Hospital, Helsinki, FinlandMinerva Foundation Institute for Medical Research, Helsinki, Finland PubMed articlesGoogle scholar articles
  • Luca Valenti Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milano, ItalyTranslational Medicine, Department of Transfusion Medicine and Hematology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy PubMed articlesGoogle scholar articles
  • Hiroyuki Arai Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, JapanAMED-CREST, Japan Agency for Medical Research and Development, Tokyo, JapanPresent address: Laboratory of Microenvironmental and Metabolic Health Science, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan PubMed articlesGoogle scholar articles
  • Stefano Romeo Department of Molecular and Clinical Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, SwedenClinical Nutrition Unit, Department of Medical and Surgical Science, Magna Graecia University, Catanzaro, ItalyDepartment of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden PubMed articlesGoogle scholar articles
  • Nozomu Kono Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Nozomu Kono, The University of Tokyo, Bunkyo-ku 113-0033, Japan; nozomu{at}mol.f.u-tokyo.ac.jp; Dr Stefano Romeo, Department of Clinical and Molecular Medicine, University of Gothenburg Sahlgrenska Academy, Gothenburg, Sweden; stefano.romeo{at}wlab.gu.se
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Citation

Tanaka Y, Shimanaka Y, Caddeo A, et al
LPIAT1/MBOAT7 depletion increases triglyceride synthesis fueled by high phosphatidylinositol turnover

Publication history

  • Received January 9, 2020
  • Revised February 24, 2020
  • Accepted March 11, 2020
  • First published April 6, 2020.

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