Article info

Download PDFPDF
Original research
Interleukin-1β-induced pancreatitis promotes pancreatic ductal adenocarcinoma via B lymphocyte–mediated immune suppression

Authors

  • Ryota Takahashi Division of Digestive and Liver Diseases, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA PubMed articlesGoogle scholar articles
  • Marina Macchini Division of Digestive and Liver Diseases, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USADepartment of Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy PubMed articlesGoogle scholar articles
  • Masaki Sunagawa Division of Digestive and Liver Diseases, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA PubMed articlesGoogle scholar articles
  • Zhengyu Jiang Division of Digestive and Liver Diseases, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA PubMed articlesGoogle scholar articles
  • Takayuki Tanaka Division of Digestive and Liver Diseases, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USADepartment of Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan PubMed articlesGoogle scholar articles
  • Giovanni Valenti Division of Digestive and Liver Diseases, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA PubMed articlesGoogle scholar articles
  • Bernhard W Renz Division of Digestive and Liver Diseases, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USADepartment of General, Visceral and Transplantation Surgery, Hospital of the University of Munich, Munich, GermanyGerman Cancer Consortium (DKTK), partner site Munich and German Cancer Research Center (DKFZ), Heidelberg, Germany PubMed articlesGoogle scholar articles
  • Ruth A White Division of Hematology and Oncology, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA PubMed articlesGoogle scholar articles
  • Yoku Hayakawa Division of Digestive and Liver Diseases, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USADepartment of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan PubMed articlesGoogle scholar articles
  • C Benedikt Westphalen Division of Digestive and Liver Diseases, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USADepartment of Internal Medicine III, Hospital of the University of Munich, Munich, GermanyComprehensive Cancer Center Munich and German Cancer Consortium (DKTK), partner site Munich, Munich, Germany PubMed articlesGoogle scholar articles
  • Yagnesh Tailor Division of Digestive and Liver Diseases, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA PubMed articlesGoogle scholar articles
  • Alina C Iuga Department of Pathology and Cell Biology, Columbia University College of Physicians and Surgeons, New York, New York, USA PubMed articlesGoogle scholar articles
  • Tamas A Gonda Division of Digestive and Liver Diseases, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA PubMed articlesGoogle scholar articles
  • Jeanine Genkinger Mailman School of Public Health, Columbia University, New York, New York, USA PubMed articlesGoogle scholar articles
  • Kenneth P Olive Division of Digestive and Liver Diseases, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA PubMed articlesGoogle scholar articles
  • Timothy C Wang Division of Digestive and Liver Diseases, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Timothy C Wang, Division of Digestive and Liver Diseases, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA; tcw21{at}columbia.edu
View Full Text

Citation

Takahashi R, Macchini M, Sunagawa M, et al
Interleukin-1β-induced pancreatitis promotes pancreatic ductal adenocarcinoma via B lymphocyte–mediated immune suppression

Publication history

  • Received September 23, 2019
  • Revised March 25, 2020
  • Accepted April 18, 2020
  • First published May 10, 2020.

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.