Footnotes

• X-lX, KK-yW and S-qC are joint first authors.

• Twitter @hk_kennethwong, @xiaokang8290150@gmail.com

• Correction notice This article has been corrected since it published Online First. The author affiliations 1, 3, 4, 5 and 9 have been amended.

• Contributors Acquisition, analysis and interpretation of data: X-lX, KW, S-qC, A-fZ, J-qT and L-sZ; drafting the work or revising it critically for important intellectual content: KW, PH-yC, GC, KT, IW, CC, XL, MY-wK, G-qC, KL, WH-sW, MH-kH and GC-fC; final approval of the version published and agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work: PI, PC, S-tT and PT.

• Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

• Competing interests None declared.

• Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research.

• Patient consent for publication Not required.

• Ethics approval This study was approved by the Research Ethics Board of Wuhan Children's Hospital (WHCH2020022).

• Provenance and peer review Not commissioned; externally peer reviewed.