Integrated genomic profiling and modelling for risk stratification in patients with advanced oesophagogastric adenocarcinoma

Dapeng Hao; Siyuan He; Kazuto Harada; Melissa Pool Pizzi; Yang Lu; Pujun Guan; Lu Chen; Ruiping Wang; Shaojun Zhang; Matheus Sewastjanow-Silva; Ahmed Abdelhakeem; Namita Shanbhag; Manoop Bhutani; Guangchun Han; Jeffrey H Lee; Shuangtao Zhao; Brian Weston; Mariela Blum Murphy; Rebecca Waters; Jeannelyn Santiano Estrella; Sinchita Roy-Chowdhuri; Qiong Gan; Ju-Seog Lee; Guang Peng; Samir M Hanash; George Adrian Calin; Xingzhi Song; Jianhua Zhang; Shumei Song; Linghua Wang; Jaffer A Ajani

doi:10.1136/gutjnl-2020-322707

Article info

Upper GI cancer

Original research

Integrated genomic profiling and modelling for risk stratification in patients with advanced oesophagogastric adenocarcinoma

Authors

Dapeng Hao Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Siyuan He Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Kazuto Harada Gastroenterological Surgery, Kumamoto University, Kumamoto, Kumamoto, Japan PubMed articles Google scholar articles
Melissa Pool Pizzi Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Yang Lu Department of Nuclear Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Pujun Guan Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Lu Chen Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Ruiping Wang Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Shaojun Zhang Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Matheus Sewastjanow-Silva Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Ahmed Abdelhakeem Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Namita Shanbhag Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Manoop Bhutani Gastroenterology Hepatology and Nutrition, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Guangchun Han Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Jeffrey H Lee Gastroenterology Hepatology and Nutrition, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Shuangtao Zhao Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Brian Weston Gastroenterology Hepatology and Nutrition, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Mariela Blum Murphy Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Rebecca Waters Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Jeannelyn Santiano Estrella Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Sinchita Roy-Chowdhuri Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Qiong Gan Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Ju-Seog Lee Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Guang Peng Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Samir M Hanash Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
George Adrian Calin Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Xingzhi Song Computational Genomics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Jianhua Zhang Computational Genomics, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Shumei Song Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Linghua Wang Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles
Jaffer A Ajani Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA PubMed articles Google scholar articles

Correspondence to Dr Jaffer A Ajani, Departments of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; jajani{at}mdanderson.org; Dr Linghua Wang, Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; LWang22{at}mdanderson.org

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Citation

Hao D, He S, Harada K, et al

Integrated genomic profiling and modelling for risk stratification in patients with advanced oesophagogastric adenocarcinoma

Gut 2021;70:2055-2065.

Publication history

Received August 7, 2020
Revised November 25, 2020
Accepted November 28, 2020
First published December 17, 2020.

Online issue publication

November 15, 2022

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