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Original research
PBMC transcriptomics identifies immune-metabolism disorder during the development of HBV-ACLF

Authors

  • Jiang Li State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China PubMed articlesGoogle scholar articles
  • Xi Liang Precision Medicine Center, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, ChinaInstitute of Pharmaceutical Biotechnology, Zhejiang University School of Medicine, Hangzhou, China PubMed articlesGoogle scholar articles
  • Jing Jiang State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaPrecision Medicine Center, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, China PubMed articlesGoogle scholar articles
  • Lingling Yang State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China PubMed articlesGoogle scholar articles
  • Jiaojiao Xin State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaPrecision Medicine Center, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, China PubMed articlesGoogle scholar articles
  • Dongyan Shi State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaPrecision Medicine Center, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, China PubMed articlesGoogle scholar articles
  • Yingyan Lu Key Laboratory of Cancer Prevention and Therapy Combining Traditional Chinese and Western Medicine, Tongde Hospital of Zhejiang Province, Hangzhou, China PubMed articlesGoogle scholar articles
  • Jun Li Department of Pathology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China PubMed articlesGoogle scholar articles
  • Keke Ren State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China PubMed articlesGoogle scholar articles
  • Hozeifa Mohamed Hassan State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China PubMed articlesGoogle scholar articles
  • Jianing Zhang The State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou, China PubMed articlesGoogle scholar articles
  • Pengcheng Chen Institute of Pharmaceutical Biotechnology, Zhejiang University School of Medicine, Hangzhou, China PubMed articlesGoogle scholar articles
  • Heng Yao State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China PubMed articlesGoogle scholar articles
  • Jiaqi Li State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China PubMed articlesGoogle scholar articles
  • Tianzhou Wu Precision Medicine Center, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, China PubMed articlesGoogle scholar articles
  • Linfeng Jin State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China PubMed articlesGoogle scholar articles
  • Ping Ye State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China PubMed articlesGoogle scholar articles
  • Tan Li State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China PubMed articlesGoogle scholar articles
  • Huafen Zhang State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China PubMed articlesGoogle scholar articles
  • Suwan Sun State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China PubMed articlesGoogle scholar articles
  • Beibei Guo State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China PubMed articlesGoogle scholar articles
  • Xingping Zhou State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China PubMed articlesGoogle scholar articles
  • Qun Cai State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China PubMed articlesGoogle scholar articles
  • Jiaxian Chen State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China PubMed articlesGoogle scholar articles
  • Xiaowei Xu State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China PubMed articlesGoogle scholar articles
  • Jianrong Huang State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China PubMed articlesGoogle scholar articles
  • Shaorui Hao State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China PubMed articlesGoogle scholar articles
  • Jinqiu He The Liver Disease Department, The Ninth Hospital of Nanchang, Nanchang, China PubMed articlesGoogle scholar articles
  • Shaojie Xin Department of Liver and Infectious Diseases, The Fifth Medical Center of PLA General Hospital, Beijing, China PubMed articlesGoogle scholar articles
  • Di Wang Institute of Immunology, Zhejiang University School of Medicine, Hangzhou, China PubMed articlesGoogle scholar articles
  • Jonel Trebicka Translational Hepatology, Department of Internal Medicine I, University Clinic Frankfurt, Frankfurt, GermanyEF Clif, European Foundation for the Study of Chronic Liver Failure, Barcelona, Spain PubMed articlesGoogle scholar articles
  • Xin Chen Institute of Pharmaceutical Biotechnology and the First Affiliated Hospital Department of Radiation Oncology, Zhejiang University School of Medicine, Hangzhou, 310058, ChinaJoint Institute for Genetics and Genome Medicine between Zhejiang University and University of Toronto, Zhejiang University, Hangzhou, China PubMed articlesGoogle scholar articles
  • Jun Li­ State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, ChinaPrecision Medicine Center, Taizhou Central Hospital (Taizhou University Hospital), Taizhou, China PubMed articlesGoogle scholar articles
  • Chinese Group on the Study of Severe Hepatitis B (COSSH)
    Google scholar articles
  1. Correspondence to Professor Jun Li, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Zhejiang University School of Medicine First Affiliated Hospital, Hangzhou, Zhejiang, China; lijun2009{at}zju.edu.cn; Professor Xin Chen; xinchen{at}zju.edu.cn; Professor Jonel Trebicka; jonel.trebicka{at}efclif.com; Professor Di Wang; diwang{at}zju.edu.cn
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Citation

Li J, Liang X, Jiang J Chinese Group on the Study of Severe Hepatitis B (COSSH), et al
PBMC transcriptomics identifies immune-metabolism disorder during the development of HBV-ACLF

Publication history

  • Received October 17, 2020
  • Revised December 25, 2020
  • Accepted December 26, 2020
  • First published January 11, 2021.
  • Supplementary Data

    This web only file has been produced by the BMJ Publishing Group from an electronic file supplied by the author(s) and has not been edited for content.

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