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Contributors JB wrote the manuscript.
Funding This study was supported by grants from Independent Research Fund Denmark (DFF), Medical Sciences and the Novo Nordisk Foundation. JB is the 2015 recipient of the Novo Nordisk Prize and the 2019 recipient of a Distinguished Investigator grant from the Novo Nordisk Foundation. The content is solely the responsibility of the author and does not necessarily represent the official views of the funders.
Competing interests None declared.
Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research.
Patient consent for publication Not required.
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