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Original research
Human and preclinical studies of the host–gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health

Authors

  • François Brial UMRS 1124 INSERM, Université de Paris Descartes, Paris, France PubMed articlesGoogle scholar articles
  • Julien Chilloux Section of Biomolecular Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK PubMed articlesGoogle scholar articles
  • Trine Nielsen Novo Nordisk Foundation Centre for Basic Metabolic Research, University of Copenhagen, Kobenhavn, Denmark PubMed articlesGoogle scholar articles
  • Sara Vieira-Silva Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute for Medical Research, Katholieke Universiteit Leuven, Leuven, Belgium PubMed articlesGoogle scholar articles
  • Gwen Falony Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute for Medical Research, Katholieke Universiteit Leuven, Leuven, Belgium PubMed articlesGoogle scholar articles
  • Petros Andrikopoulos Section of Biomolecular Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK National Heart & Lung Institute, Section of Genomic & Environmental Medicine, Imperial College London, London, UK PubMed articlesGoogle scholar articles
  • Michael Olanipekun Section of Biomolecular Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK National Heart & Lung Institute, Section of Genomic & Environmental Medicine, Imperial College London, London, UK PubMed articlesGoogle scholar articles
  • Lesley Hoyles Department of Biosciences, Nottingham Trent University, Nottingham, UK PubMed articlesGoogle scholar articles
  • Fatima Djouadi Centre de Recherche des Cordeliers, Université Paris Descartes, Paris, France Centre de Recherche des Cordeliers, INSERM, Sorbonne Université, Paris, France PubMed articlesGoogle scholar articles
  • Ana L Neves Section of Biomolecular Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK PubMed articlesGoogle scholar articles
  • Andrea Rodriguez-Martinez Section of Biomolecular Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK PubMed articlesGoogle scholar articles
  • Ghiwa Ishac Mouawad UMRS 1124 INSERM, Université de Paris Descartes, Paris, France PubMed articlesGoogle scholar articles
  • Nicolas Pons Metagenopolis, INRAE, Paris, Île-de-France, France PubMed articlesGoogle scholar articles
  • Sofia Forslund Forslund Lab, Max Delbrück Centrum für Molekulare Medizin Experimental and Clinical Research Center, Berlin, Berlin, Germany PubMed articlesGoogle scholar articles
  • Emmanuelle Le-chatelier Metagenopolis, INRAE, Paris, Île-de-France, France PubMed articlesGoogle scholar articles
  • Aurélie Le Lay UMRS 1124 INSERM, Université de Paris Descartes, Paris, France PubMed articlesGoogle scholar articles
  • Jeremy Nicholson Section of Biomolecular Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK PubMed articlesGoogle scholar articles
  • Torben Hansen Novo Nordisk Foundation Centre for Basic Metabolic Research, University of Copenhagen, Kobenhavn, Denmark PubMed articlesGoogle scholar articles
  • Tuulia Hyötyläinen Department of Chemistry, Örebro University, Örebro, Sweden PubMed articlesGoogle scholar articles
  • Karine Clément INSERM, U1166, team 6 Nutriomique, Université Pierre et Marie Curie-Paris 6, Paris, France Institute of Cardiometabolism and Nutrition (ICAN), Assistance Publique-Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Paris, France PubMed articlesGoogle scholar articles
  • Matej Oresic School of Medical Sciences, Örebro Universitet, Orebro, Sweden PubMed articlesGoogle scholar articles
  • Peer Bork Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany PubMed articlesGoogle scholar articles
  • Stanislav Dusko Ehrlich Metagenopolis, INRAE, Paris, Île-de-France, France Center for Host Microbiome Interactions, King's College London Dental Institute, London, UK PubMed articlesGoogle scholar articles
  • Jeroen Raes Laboratory of Molecular Bacteriology, Department of Microbiology and Immunology, Rega Institute for Medical Research, Katholieke Universiteit Leuven, Leuven, Belgium Center for Microbiology, Vlaams Instituut voor Biotechnologie, Leuven, Belgium PubMed articlesGoogle scholar articles
  • Oluf Borbye Pedersen Novo Nordisk Foundation Centre for Basic Metabolic Research, University of Copenhagen, Kobenhavn, Denmark PubMed articlesGoogle scholar articles
  • Dominique Gauguier UMRS 1124 INSERM, Université de Paris Descartes, Paris, France McGill Genome Centre & Department of Human Genetics, McGill University, Montréal, Québec, Canada PubMed articlesGoogle scholar articles
  • Marc-Emmanuel Dumas Section of Biomolecular Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK National Heart & Lung Institute, Section of Genomic & Environmental Medicine, Imperial College London, London, UK McGill Genome Centre & Department of Human Genetics, McGill University, Montréal, Québec, Canada European Genomics Institute for Diabetes,INSERM U1283, CNRS UMR8199, Institut Pasteur de Lille, Lille University Hospital, Unversity of Lille, Lille, France PubMed articlesGoogle scholar articles
  1. Correspondence to Professor Marc-Emmanuel Dumas, Dept of Metabolism Digestion and Reproduction, Section of Computational and Systems Medicine, Imperial College London, London, UK; m.dumas{at}imperial.ac.uk
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Citation

Brial F, Chilloux J, Nielsen T, et al
Human and preclinical studies of the host–gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health

Publication history

  • Received October 8, 2020
  • Revised April 15, 2021
  • Accepted April 18, 2021
  • First published May 11, 2021.

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