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We read with interest the letter from Cao et al 1, and thank them for the interest in our study.2 The authors are concerned about our prevalence estimates of acute-on-chronic liver failure (ACLF) in East Asia. They attributed the difference due to our inclusion of overlapping cohorts,3–6 or failing to include two additional studies.7 8
Cao et al propose to exclude one of the two included studies published in China.3 4 While both cohorts indeed come from the same hospital around the same dates, they provide a different number of participants raising the possibility of …
AJ and GM are co-first authors.
Contributors All authors contributed to the design, draft and final review of the letter.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research.
Provenance and peer review Not commissioned; internally peer reviewed.
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