Diet or medication in primary care patients with IBS: the DOMINO study - a randomised trial supported by the Belgian Health Care Knowledge Centre (KCE Trials Programme) and the Rome Foundation Research Institute

Florencia Carbone; Karen Van den Houte; Linde Besard; Céline Tack; Joris Arts; Philip Caenepeel; Hubert Piessevaux; Alain Vandenberghe; Christophe Matthys; Jessica Biesiekierski; Luc Capiau; Steven Ceulemans; Olivier Gernay; Lydia Jones; Sophie Maes; Christian Peetermans; Willem Raat; Jeroen Stubbe; Rudy Van Boxstael; Olivia Vandeput; Sophie Van Steenbergen; Lukas Van Oudenhove; Tim Vanuytsel; Michael Jones; Jan Tack

doi:10.1136/gutjnl-2021-325821

Article info

Irritable bowel syndrome

Diet or medication in primary care patients with IBS: the DOMINO study - a randomised trial supported by the Belgian Health Care Knowledge Centre (KCE Trials Programme) and the Rome Foundation Research Institute

Authors

Florencia Carbone Department of Gastroenterology, KU Leuven University Hospitals Leuven, Leuven, Belgium TARGID (Translational Research Center for Gastrointestinal Disorders), KU Leuven, Leuven, Belgium PubMed articles Google scholar articles
Karen Van den Houte TARGID (Translational Research Center for Gastrointestinal Disorders), KU Leuven, Leuven, Belgium PubMed articles Google scholar articles
Linde Besard Department of Gastroenterology, KU Leuven University Hospitals Leuven, Leuven, Belgium PubMed articles Google scholar articles
Céline Tack Department of Gastroenterology, KU Leuven University Hospitals Leuven, Leuven, Belgium PubMed articles Google scholar articles
Joris Arts Department of Gastroenterology, KU Leuven University Hospitals Leuven, Leuven, Belgium Gastroenterology, Ziekenhuis Oost-Limburg, Genk, Belgium PubMed articles Google scholar articles
Philip Caenepeel Department of Gastroenterology, KU Leuven University Hospitals Leuven, Leuven, Belgium Gastroenterology, Ziekenhuis Oost-Limburg, Genk, Belgium PubMed articles Google scholar articles
Hubert Piessevaux Department of Gastroenterology and Hepatology, Université catholique de Louvain, Louvain-la-Neuve, Belgium PubMed articles Google scholar articles
Alain Vandenberghe Medical Research Laboratories International, Chaumont-Gistoux, Belgium PubMed articles Google scholar articles
Christophe Matthys Clinical and Experimental Endocrinology, Katholieke Universiteit Leuven, Leuven, Belgium PubMed articles Google scholar articles
Jessica Biesiekierski TARGID (Translational Research Center for Gastrointestinal Disorders), KU Leuven, Leuven, Belgium Department of Dietetics, Nutrition and Sport, La Trobe University, Melbourne, Victoria, Australia PubMed articles Google scholar articles
Luc Capiau Primary care physician, Domino primary care physician study group, Leuven, Belgium PubMed articles Google scholar articles
Steven Ceulemans Primary care physician, Domino primary care physician study group, Leuven, Belgium PubMed articles Google scholar articles
Olivier Gernay Primary care physician, Domino primary care physician study group, Leuven, Belgium PubMed articles Google scholar articles
Lydia Jones Primary care physician, Domino primary care physician study group, Leuven, Belgium PubMed articles Google scholar articles
Sophie Maes Primary care physician, Domino primary care physician study group, Leuven, Belgium PubMed articles Google scholar articles
Christian Peetermans Primary care physician, Domino primary care physician study group, Leuven, Belgium PubMed articles Google scholar articles
Willem Raat Department of Public Health and Primary Care, KU Leuven, Leuven, Belgium PubMed articles Google scholar articles
Jeroen Stubbe Primary care physician, Domino primary care physician study group, Leuven, Belgium PubMed articles Google scholar articles
Rudy Van Boxstael Primary care physician, Domino primary care physician study group, Leuven, Belgium PubMed articles Google scholar articles
Olivia Vandeput Primary care physician, Domino primary care physician study group, Leuven, Belgium PubMed articles Google scholar articles
Sophie Van Steenbergen Primary care physician, Domino primary care physician study group, Leuven, Belgium PubMed articles Google scholar articles
Lukas Van Oudenhove TARGID (Translational Research Center for Gastrointestinal Disorders), KU Leuven, Leuven, Belgium PubMed articles Google scholar articles
Tim Vanuytsel Department of Gastroenterology, KU Leuven University Hospitals Leuven, Leuven, Belgium TARGID (Translational Research Center for Gastrointestinal Disorders), KU Leuven, Leuven, Belgium PubMed articles Google scholar articles
Michael Jones Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, New South Wales, Australia PubMed articles Google scholar articles
Jan Tack Department of Gastroenterology, KU Leuven University Hospitals Leuven, Leuven, Belgium TARGID (Translational Research Center for Gastrointestinal Disorders), KU Leuven, Leuven, Belgium Rome Foundation Research Institute, Raleigh, North Carolina, USA Rome Foundation, Raleigh, North Carolina, USA PubMed articles Google scholar articles
DOMINO Study Collaborators
Google scholar articles

Correspondence to Dr Jan Tack, Gastroenterology and Hepatology, KU Leuven University Hospitals Leuven, Leuven 3000, Belgium; jan.tack{at}med.kuleuven.ac.be

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Citation

Carbone F, Van den Houte K, Besard L DOMINO Study Collaborators, et al

Gut 2022;71:2226-2232.

Publication history

Received August 9, 2021
Accepted April 13, 2022
First published April 28, 2022.

Online issue publication

May 04, 2023

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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