Article info

Original research
Protective and aggressive bacterial subsets and metabolites modify hepatobiliary inflammation and fibrosis in a murine model of PSC

Authors

  • Muyiwa Awoniyi Division of Gastroenterology and Hepatology, University of North Carolina System, Chapel Hill, North Carolina, USACenter for Gastrointestinal Biology and Disease, University of North Carolina System, Chapel Hill, North Carolina, USA PubMed articlesGoogle scholar articles
  • Jeremy Wang Center for Gastrointestinal Biology and Disease, University of North Carolina System, Chapel Hill, North Carolina, USADepartment of Genetics, University of North Carolina System, Chapel Hill, North Carolina, USA PubMed articlesGoogle scholar articles
  • Billy Ngo Center for Gastrointestinal Biology and Disease, University of North Carolina System, Chapel Hill, North Carolina, USA PubMed articlesGoogle scholar articles
  • Vik Meadows Department of Gastroenterology, Indiana University School of Medicine, Indianapolis, Indiana, USA PubMed articlesGoogle scholar articles
  • Jason Tam Department of Microbiology and Immunology, University of North Carolina System, Chapel Hill, North Carolina, USA PubMed articlesGoogle scholar articles
  • Amba Viswanathan Center for Gastrointestinal Biology and Disease, University of North Carolina System, Chapel Hill, North Carolina, USA PubMed articlesGoogle scholar articles
  • Yunjia Lai Department of Environmental Sciences and Engineering, Gillings School of Global School of Public Health, University of North Carolina System, Chapel Hill, North Carolina, USA PubMed articlesGoogle scholar articles
  • Stephanie Montgomery Department of Pathology, Division of Comparative Medicine, and Lineberger Comprehensive Cancer Center, University of North Carolina System, Chapel Hill, North Carolina, USA PubMed articlesGoogle scholar articles
  • Morgan Farmer Center for Gastrointestinal Biology and Disease, University of North Carolina System, Chapel Hill, North Carolina, USA PubMed articlesGoogle scholar articles
  • Martin Kummen Norwegian PSC Research Center, Oslo University Hospital, Rikshospitalet, Oslo, NorwayInstitute of Clinical Medicine, University of Oslo, Oslo, Norway PubMed articlesGoogle scholar articles
  • Louise Thingholm Institute of Clinical Molecular Biology, Zentrums für Molekulare Biowissenschaften, Kiel, Schleswig-Holstein, Germany PubMed articlesGoogle scholar articles
  • Christoph Schramm University Medical Centre Hamburg-Eppendorf, Hamburg, Germany PubMed articlesGoogle scholar articles
  • Corinna Bang Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany PubMed articlesGoogle scholar articles
  • Andre Franke Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany PubMed articlesGoogle scholar articles
  • Kun Lu Department of Environmental Sciences and Engineering, Gillings School of Global School of Public Health, University of North Carolina System, Chapel Hill, North Carolina, USADepartment of Environmental Sciences and Engineering, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA PubMed articlesGoogle scholar articles
  • Huiping Zhou Department of Microbiology and Immunology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, USADepartment of Research, McGuire Veterans Affairs Medical Cente, Richmond, Virginia, USAVirginia Commonwealth University Medical Center, Richmond, Virginia, USA PubMed articlesGoogle scholar articles
  • Jasmohan S Bajaj Department of Microbiology and Immunology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, USADepartment of Research, McGuire Veterans Affairs Medical Cente, Richmond, Virginia, USAVirginia Commonwealth University Medical Center, Richmond, Virginia, USA PubMed articlesGoogle scholar articles
  • Phillip B Hylemon Department of Microbiology and Immunology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, USADepartment of Research, McGuire Veterans Affairs Medical Cente, Richmond, Virginia, USAVirginia Commonwealth University Medical Center, Richmond, Virginia, USA PubMed articlesGoogle scholar articles
  • Jenny Ting Department of Microbiology and Immunology, University of North Carolina System, Chapel Hill, North Carolina, USAUNC Lineberger Comprehensive Cancer Center, Center for Translational Immunology, University of North Carolina, Chapel Hill, Chapel Hill, North Carolina, USA PubMed articlesGoogle scholar articles
  • Yury V Popov Department of Gastroenterology, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Johannes Roksund Hov Institute of Clinical Medicine, University of Oslo, Oslo, NorwayNorwegian PSC Research Center, Department of Transplantation Medicine, Oslo University Hospital, Oslo, Norway PubMed articlesGoogle scholar articles
  • Heather L Francis Indiana University School of Medicine, Indianapolis, Indiana, USARichard L. Roudebush VA Medical Center, Indianapolis, Indiana, USA PubMed articlesGoogle scholar articles
  • Ryan Balfour Sartor Division of Gastroenterology and Hepatology, University of North Carolina System, Chapel Hill, North Carolina, USACenter for Gastrointestinal Biology and Disease, University of North Carolina System, Chapel Hill, North Carolina, USADepartment of Microbiology and Immunology, University of North Carolina System, Chapel Hill, North Carolina, USA PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Ryan Balfour Sartor, Center for Gastrointestinal Biology and Disease, University of North Carolina System, Chapel Hill, NC 27517, USA; ryan_balfour_sartor{at}med.unc.edu
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Citation

Awoniyi M, Wang J, Ngo B, et al
Protective and aggressive bacterial subsets and metabolites modify hepatobiliary inflammation and fibrosis in a murine model of PSC

Publication history

  • Received November 6, 2021
  • Accepted May 16, 2022
  • First published June 15, 2022.

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