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Seronegative coeliac disease and non-coeliac enteropathies: precision medicine, precision medicine, where are you?
  1. Knut E A Lundin1,2,
  2. Peter HR Green3
  1. 1KG Jebsen Coeliac Disease Research Centre, University of Oslo Faculty of Medicine, Oslo, Norway
  2. 2Department of Gastroenterology, OUS Rikshospitalet, Oslo University Hospital, Oslo, Norway
  3. 3Celiac Disease Center at Columbia University, Columbia University, New York, New York, USA
  1. Correspondence to Dr Knut E A Lundin, KG Jebsen Coeliac Disease Research Centre, University of Oslo Faculty of Medicine, Oslo, Norway; knut.lundin{at}

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In a very recent and welcome article, Schiepatti et al address a challenging field of gastroenterology.1 Whereas the diagnosis of coeliac disease in most cases is simple, although overlooked, there are other circumstances where this is much more difficult. There are also several other causes of villous atrophy, the hallmark of coeliac disease, that may be considered, although coeliac disease is by far the most frequent cause of those pathological findings. The author group shall be acknowledged for their effort. The critical question, however, remains: are the clinicians better helped with the current publication?

The group of investigators were recruited during the most recent International Coeliac Disease Symposium in Paris, France in the autumn of 2019. These symposia have regularly been arranged since its first start in London in 1970. These symposia have, during recent years, repeatedly been followed by guideline and statement papers, most of which have been published in Gut.2–5 This time, the authors gathered a group of world-leading experts on coeliac disease, but, unfortunately, no (molecular) pathologists and no immunologists on board. In addition, there were wide regions of the world not represented. …

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  • Contributors The manuscript was prepared by both authors. Submission was agreed.

  • Funding This study was funded by Stiftelsen Kristian Gerhard Jebsen, South East Regional Health Authority.

  • Competing interests None declared.

  • Provenance and peer review Commissioned; internally peer reviewed.

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