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Original research
Cell-based cccDNA reporter assay combined with functional genomics identifies YBX1 as HBV cccDNA host factor and antiviral candidate target

Authors

  • Eloi R Verrier Université de Strasbourg, Inserm, Institut de Recherche sur les Maladies Virales et Hépatiques UMRS 1110, Strasbourg, France PubMed articlesGoogle scholar articles
  • Gaëtan Ligat Université de Strasbourg, Inserm, Institut de Recherche sur les Maladies Virales et Hépatiques UMRS 1110, Strasbourg, France PubMed articlesGoogle scholar articles
  • Laura Heydmann Université de Strasbourg, Inserm, Institut de Recherche sur les Maladies Virales et Hépatiques UMRS 1110, Strasbourg, France PubMed articlesGoogle scholar articles
  • Katharina Doernbrack Department of Internal Medicine II/Molecular Biology, University Hospital Freiburg, Freiburg, Germany PubMed articlesGoogle scholar articles
  • Julija Miller Department of Internal Medicine II/Molecular Biology, University Hospital Freiburg, Freiburg, Germany PubMed articlesGoogle scholar articles
  • Anne Maglott-Roth IGBMC, Plateforme de Criblage Haut-débit, Illkirch, France PubMed articlesGoogle scholar articles
  • Frank Jühling Université de Strasbourg, Inserm, Institut de Recherche sur les Maladies Virales et Hépatiques UMRS 1110, Strasbourg, France PubMed articlesGoogle scholar articles
  • Houssein El Saghire Université de Strasbourg, Inserm, Institut de Recherche sur les Maladies Virales et Hépatiques UMRS 1110, Strasbourg, France PubMed articlesGoogle scholar articles
  • Margaux J Heuschkel Université de Strasbourg, Inserm, Institut de Recherche sur les Maladies Virales et Hépatiques UMRS 1110, Strasbourg, France PubMed articlesGoogle scholar articles
  • Naoto Fujiwara Department of Internal Medicine, Liver Tumor Translational Research Program, Simmons Comprehensive Cancer Center, Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, Texas, USA PubMed articlesGoogle scholar articles
  • Sen-Yung Hsieh Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Taoyuan, Taiwan PubMed articlesGoogle scholar articles
  • Yujin Hoshida Department of Internal Medicine, Liver Tumor Translational Research Program, Simmons Comprehensive Cancer Center, Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, Texas, USA PubMed articlesGoogle scholar articles
  • David E Root Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Emanuele Felli Université de Strasbourg, Inserm, Institut de Recherche sur les Maladies Virales et Hépatiques UMRS 1110, Strasbourg, France Institut Hospitalo-Universitaire, Pôle Hépato-digestif, Nouvel Hôpital Civil, Strasbourg, France PubMed articlesGoogle scholar articles
  • Patrick Pessaux Université de Strasbourg, Inserm, Institut de Recherche sur les Maladies Virales et Hépatiques UMRS 1110, Strasbourg, France Institut Hospitalo-Universitaire, Pôle Hépato-digestif, Nouvel Hôpital Civil, Strasbourg, France PubMed articlesGoogle scholar articles
  • Atish Mukherji Université de Strasbourg, Inserm, Institut de Recherche sur les Maladies Virales et Hépatiques UMRS 1110, Strasbourg, France PubMed articlesGoogle scholar articles
  • Laurent Mailly Université de Strasbourg, Inserm, Institut de Recherche sur les Maladies Virales et Hépatiques UMRS 1110, Strasbourg, France PubMed articlesGoogle scholar articles
  • Catherine Schuster Université de Strasbourg, Inserm, Institut de Recherche sur les Maladies Virales et Hépatiques UMRS 1110, Strasbourg, France PubMed articlesGoogle scholar articles
  • Laurent Brino IGBMC, Plateforme de Criblage Haut-débit, Illkirch, France PubMed articlesGoogle scholar articles
  • Michael Nassal Department of Internal Medicine II/Molecular Biology, University Hospital Freiburg, Freiburg, Germany PubMed articlesGoogle scholar articles
  • Thomas F. Baumert Université de Strasbourg, Inserm, Institut de Recherche sur les Maladies Virales et Hépatiques UMRS 1110, Strasbourg, France Institut Hospitalo-Universitaire, Pôle Hépato-digestif, Nouvel Hôpital Civil, Strasbourg, France PubMed articlesGoogle scholar articles
  1. Correspondence to Prof. Thomas F. Baumert, Strasbourg, France; Thomas.Baumert{at}unistra.fr; Dr Eloi R Verrier, Strasbourg, France; e.verrier{at}unistra.fr; Professor Michael Nassal, Freiburg, Germany; michael.nassal{at}uniklinik-freiburg.de
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Citation

Verrier ER, Ligat G, Heydmann L, et al
Cell-based cccDNA reporter assay combined with functional genomics identifies YBX1 as HBV cccDNA host factor and antiviral candidate target
Online issue publication 
February 16, 2024

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