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Hepatology
Original research
Distinct single-cell immune ecosystems distinguish true and de novo HBV-related hepatocellular carcinoma recurrences

Authors

  • Shuling Chen Center of Hepato-Pancreato-Biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China Institute of Diagnostic and Interventional Ultrasound, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China Precision Medicine Institute, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China PubMed articlesGoogle scholar articles
  • Cheng Huang Department of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China PubMed articlesGoogle scholar articles
  • Guanrui Liao Center of Hepato-Pancreato-Biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China PubMed articlesGoogle scholar articles
  • Huichuan Sun Department of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China PubMed articlesGoogle scholar articles
  • Yubin Xie Precision Medicine Institute, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China PubMed articlesGoogle scholar articles
  • Changyi Liao Department of Oncology, Cancer Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China PubMed articlesGoogle scholar articles
  • Jianping Wang Department of Gastroenterology and Hepatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China PubMed articlesGoogle scholar articles
  • Minghui He Center of Hepato-Pancreato-Biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China PubMed articlesGoogle scholar articles
  • Huanjing Hu Precision Medicine Institute, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China PubMed articlesGoogle scholar articles
  • Zihao Dai Center of Hepato-Pancreato-Biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China Precision Medicine Institute, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China PubMed articlesGoogle scholar articles
  • Xiaoxue Ren Department of Oncology, Cancer Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China PubMed articlesGoogle scholar articles
  • Xuezhen Zeng Precision Medicine Institute, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China PubMed articlesGoogle scholar articles
  • Zhilong Lin Center of Hepato-Pancreato-Biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China PubMed articlesGoogle scholar articles
  • Guo-Pei Zhang Center of Hepato-Pancreato-Biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China PubMed articlesGoogle scholar articles
  • Wenxuan Xie Center of Hepato-Pancreato-Biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China PubMed articlesGoogle scholar articles
  • Shunli Shen Center of Hepato-Pancreato-Biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China PubMed articlesGoogle scholar articles
  • Shaoqiang Li Center of Hepato-Pancreato-Biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China PubMed articlesGoogle scholar articles
  • Sui Peng Precision Medicine Institute, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China Department of Gastroenterology and Hepatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China Clinical Trials Unit, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China PubMed articlesGoogle scholar articles
  • Dong-Ming Kuang State Key Laboratory of Oncology in South China, Cancer Center, MOE Key Laboratory of Gene Function and Regulation, School of Life Sciences, Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China PubMed articlesGoogle scholar articles
  • Qiang Zhao Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China Guangdong Provincial Key Laboratory of Organ Donation and Transplant Immunology, Guangzhou, Guangdong, People's Republic of China PubMed articlesGoogle scholar articles
  • Dan G Duda Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Ming Kuang Center of Hepato-Pancreato-Biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China PubMed articlesGoogle scholar articles
  1. Correspondence to Professor Ming Kuang, The First Affiliated Hospital, Center of Hepato-Pancreato-Biliary Surgery, Sun Yat-Sen University, Guangzhou, Guangdong, China; kuangm{at}mail.sysu.edu.cn; Dr Dan G Duda; duda{at}steele.mgh.harvard.edu; Qiang Zhao; zhaoq37{at}mail.sysu.edu.cn
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Citation

Chen S, Huang C, Liao G, et al
Distinct single-cell immune ecosystems distinguish true and de novo HBV-related hepatocellular carcinoma recurrences
Gut 2023;72:1196-1210.

Publication history

  • Received August 5, 2022
  • Accepted November 24, 2022
  • First published January 3, 2023.
Online issue publication 
May 31, 2023

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© Author(s) (or their employer(s)) 2023. No commercial re-use. See rights and permissions. Published by BMJ.