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We have read with great interest the recently published Lyon Consensus 2.0 in Gut, which provides updates to the modern diagnosis of gastro-oesophageal reflux disease (GORD).1 GORD is one of the most common GI disorders affecting nearly a quarter of individuals in the USA.2 3 As symptoms alone are not sufficient to establish a diagnosis of conclusive GORD, objective testing with an esophagogastroduodenoscopy (EGD) and/or pH monitoring is often recommended prior to initiating long-term acid suppression.1 4
Prolonged wireless pH-monitoring off acid suppression for up to 96 hours is often recommended as the preferred testing modality for unproven GORD as it better accounts for day-to-day variability in oesophageal acid exposure and may be better tolerated than 24-hour …
Contributors AKK, AR: study concept and design; data analysis and interpretation; drafting of the manuscript; critical revision of the manuscript for important intellectual content. YC, JN, JEL, BWC: drafting of the manuscript; critical revision of the manuscript for important intellectual content.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Provenance and peer review Not commissioned; internally peer reviewed.