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Original research
KLHL21 suppresses gastric tumourigenesis via maintaining STAT3 signalling equilibrium in stomach homoeostasis

Authors

  • Xiao-Bo Huang Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaKey Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaFujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fujian, China PubMed articlesGoogle scholar articles
  • Qiang Huang Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaKey Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaFujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fujian, China PubMed articlesGoogle scholar articles
  • Mei-Chen Jiang Diagnostic Pathology, Fujian Medical University Union Hospital, Fuzhou, China PubMed articlesGoogle scholar articles
  • Qing Zhong Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaKey Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaFujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fujian, China PubMed articlesGoogle scholar articles
  • Hua-Long Zheng Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaKey Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaFujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fujian, China PubMed articlesGoogle scholar articles
  • Jia-Bin Wang Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaKey Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaFujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fujian, China PubMed articlesGoogle scholar articles
  • Ze-Ning Huang Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaKey Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaFujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fujian, China PubMed articlesGoogle scholar articles
  • Hua-Gen Wang Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaKey Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaFujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fujian, China PubMed articlesGoogle scholar articles
  • Zhi-Yu Liu Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaKey Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaFujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fujian, China PubMed articlesGoogle scholar articles
  • Yi-Fan Li Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaKey Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaFujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fujian, China PubMed articlesGoogle scholar articles
  • Kai-Xiang Xu Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaKey Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaFujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fujian, China PubMed articlesGoogle scholar articles
  • Mi Lin Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaKey Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaFujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fujian, China PubMed articlesGoogle scholar articles
  • Ping Li Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaKey Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaFujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fujian, China PubMed articlesGoogle scholar articles
  • Zhi-Hong Huang Public Technology Service Center, Fujian Medical University, Fuzhou, China PubMed articlesGoogle scholar articles
  • Jian-Wei Xie Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaKey Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaFujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fujian, China PubMed articlesGoogle scholar articles
  • Jian-Xian Lin Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaKey Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaFujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fujian, China PubMed articlesGoogle scholar articles
  • Jun Lu Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaKey Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaFujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fujian, China PubMed articlesGoogle scholar articles
  • Jian-Wen Que Columbia Center for Human Development, Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, New York, USADivision of Digestive and Liver Diseases, Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, New York, USAHerbert Irving Comprehensive Cancer Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, New York, USA PubMed articlesGoogle scholar articles
  • Chao-Hui Zheng Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaKey Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaFujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fujian, China PubMed articlesGoogle scholar articles
  • Qi-Yue Chen Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaKey Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaFujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fujian, China PubMed articlesGoogle scholar articles
  • Chang-Ming Huang Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaKey Laboratory of Ministry of Education of Gastrointestinal Cancer, Fujian Medical University, Fuzhou, ChinaFujian Key Laboratory of Tumor Microbiology, Fujian Medical University, Fujian, China PubMed articlesGoogle scholar articles
  1. Correspondence to Professor Chang-Ming Huang, Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian, China; hcmlr2002{at}163.com; Professor Qi-Yue Chen, Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian, China; 690934662{at}qq.com; Professor Chao-Hui Zheng, Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian, China; wwkzch{at}163.com
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Citation

Huang X, Huang Q, Jiang M, et al
KLHL21 suppresses gastric tumourigenesis via maintaining STAT3 signalling equilibrium in stomach homoeostasis

Publication history

  • Received September 11, 2023
  • Accepted June 13, 2024
  • First published July 5, 2024.

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