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BMJ Journals More

Online First

April 06, 2020

Hepatology
LPIAT1/MBOAT7 depletion increases triglyceride synthesis fueled by high phosphatidylinositol turnover

Yuki Tanaka, Yuta Shimanaka, Andrea Caddeo, Takuya Kubo, Yanli Mao, Tetsuya Kubota, Naoto Kubota, Toshimasa Yamauchi, Rosellina Margherita Mancina, Guido Baselli, Panu Luukkonen, Jussi Pihlajamäki, Hannele Yki-Järvinen, Luca Valenti, Hiroyuki Arai, Stefano Romeo, Nozomu Kono

doi: 10.1136/gutjnl-2020-320646
PostScript
Chronic liver disease negatively affects outcome in hospitalised patients with community-acquired pneumonia

Carla Bellinghausen, Mathias W Pletz, Jan Rupp, Martin Witzenrath, Christoph Welsch, Stefan Zeuzem, Jonel Trebicka, Gernot G U Rohde Members of the CAPNETZ study group

doi: 10.1136/gutjnl-2020-320876

April 03, 2020

Endoscopy
BowelScope: Accuracy of Detection Using Endocuff Optimisation of Mucosal Abnormalities (the B-ADENOMA Study): a multicentre, randomised controlled flexible sigmoidoscopy trial

Colin J Rees, Andrew Brand, Wee Sing Ngu, Clive Stokes, Zoe Hoare, Nicola Totton, Pradeep Bhandari, Linda Sharp, Alexandra Bastable, Matthew D Rutter, Ajay Mark Verma, Thomas J Lee, Martin Walls The B-ADENOMA trial group comprises

doi: 10.1136/gutjnl-2019-319621
Pancreas
Design and validation of a patient-reported outcome measure scale in acute pancreatitis: the PAN-PROMISE study

Enrique de-Madaria, Claudia Sánchez-Marin, Irene Carrillo, Santhi Swaroop Vege, Serge Chooklin, Andriy Bilyak, Rafael Mejuto, Violeta Mauriz, Peter Hegyi, Katalin Márta, Ayesha Kamal, Eugenia Lauret-Braña, Sorin T Barbu, Vitor Nunes, M Lourdes Ruiz-Rebollo, Guillermo García-Rayado, Edgard E Lozada-Hernandez, Jorge Pereira, Ionut Negoi, Silvia Espina, Marcus Hollenbach, Andrey Litvin, Federico Bolado-Concejo, Rómulo D Vargas, Isabel Pascual-Moreno, Vikesh K Singh, José J Mira

doi: 10.1136/gutjnl-2020-320729
PostScript
Fibrosis-4 (FIB-4) score at the primary care level: an analysis of over 160 000 blood samples

David Petroff, Olaf Bätz, Katrin Jedrysiak, Jan Kramer, Thomas Berg, Johannes Wiegand

doi: 10.1136/gutjnl-2020-320995
PostScript
A fatal case of COVID-19 pneumonia occurring in a patient with severe acute ulcerative colitis
Free

Stefano Mazza, Andrea Sorce, Flora Peyvandi, Maurizio Vecchi, Flavio Caprioli

doi: 10.1136/gutjnl-2020-321183
Hepatology
TGF-β2 silencing to target biliary-derived liver diseases

Anne Dropmann, Steven Dooley, Bedair Dewidar, Seddik Hammad, Tatjana Dediulia, Julia Werle, Vanessa Hartwig, Shahrouz Ghafoory, Stefan Woelfl, Hanna Korhonen, Michel Janicot, Katja Wosikowski, Timo Itzel, Andreas Teufel, Detlef Schuppan, Ana Stojanovic, Adelheid Cerwenka, Stefanie Nittka, Albrecht Piiper, Timo Gaiser, Naiara Beraza, Malgorzata Milkiewicz, Piotr Milkiewicz, John G Brain, David E J Jones, Thomas S Weiss, Ulrich M Zanger, Matthias Ebert, Nadja M Meindl-Beinker

doi: 10.1136/gutjnl-2019-319091

April 02, 2020

Hepatology
Differential inflammasome activation predisposes to acute-on-chronic liver failure in human and experimental cirrhosis with and without previous decompensation

Sofia Monteiro, Josephine Grandt, Frank Erhard Uschner, Nina Kimer, Jan Lysgård Madsen, Robert Schierwagen, Sabine Klein, Christoph Welsch, Liliana Schäfer, Christian Jansen, Joan Claria, José Alcaraz-Quiles, Vicente Arroyo, Richard Moreau, Javier Fernandez, Flemming Bendtsen, Gautam Mehta, Lise Lotte Gluud, Søren Møller, Michael Praktiknjo, Jonel Trebicka

doi: 10.1136/gutjnl-2019-320170
Upper GI cancer
Effectiveness of one-time endoscopic screening programme in prevention of upper gastrointestinal cancer in China: a multicentre population-based cohort study

Ru Chen, Yong Liu, Guohui Song, Bianyun Li, Deli Zhao, Zhaolai Hua, Xinzheng Wang, Jun Li, Changqing Hao, Liwei Zhang, Shuzheng Liu, Jialin Wang, Jinyi Zhou, Yongzhen Zhang, Bo Li, Yanyan Li, Xiang Feng, Lin Li, Zhiwei Dong, Wenqiang Wei, Guiqi Wang

doi: 10.1136/gutjnl-2019-320200
PostScript
Prevention of nosocomial SARS-CoV-2 transmission in endoscopy: international recommendations and the need for a gold standard

John Ong, Gail B Cross, Yock Young Dan

doi: 10.1136/gutjnl-2020-321154
PostScript
Effect of ACE inhibitors and angiotensin II receptor blockers on disease outcomes in inflammatory bowel disease

Keeley M Fairbrass, Deloar Hoshen, David J Gracie, Alexander C Ford

doi: 10.1136/gutjnl-2020-321186
Gut microbiota
Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents

Xifan Wang, Songtao Yang, Shenghui Li, Liang Zhao, Yanling Hao, Junjie Qin, Lian Zhang, Chengying Zhang, Weijing Bian, LI Zuo, Xiu Gao, Baoli Zhu, Xingen Lei, Zhenglong Gu, Wei Cui, Xiping Xu, Zhiming Li, Benzhong Zhu, Yuan Li, Shangwu Chen, Huiyuan Guo, Hao Zhang, Jing Sun, Ming Zhang, Yan Hui, Xiaolin Zhang, Xiaoxue Liu, Bowen Sun, Longjiao Wang, Qinglu Qiu, Yuchan Zhang, Xingqi Li, Weiqian Liu, Rui Xue, Hong Wu, DongHua Shao, Junling Li, Yuanjie Zhou, Shaochuan Li, Rentao Yang, Oluf Borbye Pedersen, Zhengquan Yu, Stanislav Dusko Ehrlich, Fazheng Ren

doi: 10.1136/gutjnl-2019-319766
Gut immunity
Gastrointestinal symptoms of 95 cases with SARS-CoV-2 infection

Lu Lin, Xiayang Jiang, Zhenling Zhang, Siwen Huang, Zhenyi Zhang, Zhaoxiong Fang, Zhiqiang Gu, Liangqing Gao, Honggang Shi, Lei Mai, Yuan Liu, Xianqi Lin, Renxu Lai, Zhixiang Yan, Xiaofeng Li, Hong Shan

doi: 10.1136/gutjnl-2020-321013
Endoscopy
Early gastric cancer detection in high-risk patients: a multicentre randomised controlled trial on the effect of second-generation narrow band imaging

Naohiro Yoshida, Hisashi Doyama, Tomonori Yano, Takahiro Horimatsu, Noriya Uedo, Yoshinobu Yamamoto, Naomi Kakushima, Hiromitsu Kanzaki, Shinichiro Hori, Kenshi Yao, Ichiro Oda, Chikatoshi Katada, Chizu Yokoi, Ken Ohata, Kenichi Yoshimura, Hideki Ishikawa, Manabu Muto

doi: 10.1136/gutjnl-2019-319631
Gut immunity
Digestive system is a potential route of COVID-19: an analysis of single-cell coexpression pattern of key proteins in viral entry process

Hao Zhang, Zijian Kang, Haiyi Gong, Da Xu, Jing Wang, Zhixiu Li, Zifu Li, Xinggang Cui, Jianru Xiao, Jian Zhan, Tong Meng, Wang Zhou, Jianmin Liu, Huji Xu

doi: 10.1136/gutjnl-2020-320953
Guidelines
Practice of endoscopy during COVID-19 pandemic: position statements of the Asian Pacific Society for Digestive Endoscopy (APSDE-COVID statements)

Philip Wai Yan Chiu, Siew C Ng, Haruhiro Inoue, D Nageshwar Reddy, Enqiang Ling Hu, Joo Young Cho, Lawrence KY Ho, David G Hewett, Han-Mo Chiu, Rungsun Rerknimitr, Hsiu-Po Wang, Shiaw Hooi Ho, Dong Wan Seo, Khean-Lee Goh, Hisao Tajiri, Seigo Kitano, Francis K L Chan

doi: 10.1136/gutjnl-2020-321185

March 31, 2020

PostScript
Increasing incidence of young-onset colorectal cancers in the UK and rising mortality in rectal cancers

Karl King Yong, Moe Kyaw, Georgina Chadwick, Krishna Sundaram

doi: 10.1136/gutjnl-2020-321069
Colon
Transition to quantitative faecal immunochemical testing from guaiac faecal occult blood testing in a fully rolled-out population-based national bowel screening programme

Gavin Clark, Judith A Strachan, Frank A Carey, Thomas Godfrey, Audrey Irvine, Alisson McPherson, Jess Brand, Annie S Anderson, Callum G Fraser, Robert JC Steele

doi: 10.1136/gutjnl-2019-320297

March 30, 2020

Hepatology
HBV vaccination and HBV infection induces HBV-specific natural killer cell memory

Ratna S Wijaya, Scott A Read, Naomi R Truong, Shuanglin Han, Dishen Chen, Haleh Shahidipour, Nicole L Fewings, Stephen Schibeci, Mahmoud K Azardaryany, Grant P Parnell, David Booth, David van der Poorten, Rita Lin, Jacob George, Mark W Douglas, Golo Ahlenstiel

doi: 10.1136/gutjnl-2019-319252
Hepatology
No difference in hepatocellular carcinoma risk between chronic hepatitis B patients treated with entecavir versus tenofovir

Feng Su, George N Ioannou, Kristin Berry

doi: 10.1136/gutjnl-2019-319867
PostScript
Response to letter titled ‘Reduction of HbA1c in patients with type 2 diabetes following duodenal mucosal resurfacing: could other factors be at play?’

JJGHM Bergman

doi: 10.1136/gutjnl-2020-321170

March 27, 2020

Hepatology
Mortality in biopsy-proven alcohol-related liver disease: a population-based nationwide cohort study of 3453 patients

Hannes Hagström, Maja Thiele, Bjorn Roelstraete, Jonas Söderling, Jonas F Ludvigsson

doi: 10.1136/gutjnl-2019-320446
Commentary
Non-invasive diagnosis of patients with ‘at-risk’ NAFLD : only fibrosis counts?

Andreas Geier, Jerome Boursier

doi: 10.1136/gutjnl-2020-320785
Editor’s quiz: GI snapshot
Don’t judge a book by its cover: except during optical evaluation

Neal Shahidi, W Arnout van Hattem, Sergei Vosko, Michael J Bourke

doi: 10.1136/gutjnl-2020-320829
Hepatology
Discontinuation of nucleos(t)ide analogues is not associated with a higher risk of HBsAg seroreversion after antiviral-induced HBsAg seroclearance: a nationwide multicentre study

Minseok Albert Kim, Seung Up Kim, Dong Hyun Sinn, Jeong Won Jang, Young-Suk Lim, Sang Hoon Ahn, Jae-Jun Shim, Yeon Seok Seo, Yang Hyun Baek, Sang Gyune Kim, Young Seok Kim, Ji Hoon Kim, Won Hyeok Choe, Hyung Joon Yim, Hyun Woong Lee, Jung Hyun Kwon, Sung Won Lee, Jae Young Jang, Hwi Young Kim, Yewan Park, Gi-Ae Kim, Hyun Yang, Han Ah Lee, Myeongseok Koh, Young-Sun Lee, Minkoo Kim, Young Chang, Yoon Jun Kim, Jung-Hwan Yoon, Fabien Zoulim, Jeong-Hoon Lee

doi: 10.1136/gutjnl-2019-320015

March 26, 2020

Hepatology
Targeting clinical epigenetic reprogramming for chemoprevention of metabolic and viral hepatocellular carcinoma

Frank Jühling, Nourdine Hamdane, Emilie Crouchet, Shen Li, Houssein El Saghire, Atish Mukherji, Naoto Fujiwara, Marine A Oudot, Christine Thumann, Antonio Saviano, Armando Andres Roca Suarez, Kaku Goto, Ricard Masia, Mozhdeh Sojoodi, Gunisha Arora, Hiroshi Aikata, Atsushi Ono, Parissa Tabrizian, Myron Schwartz, Stephen J Polyak, Irwin Davidson, Christian Schmidl, Christoph Bock, Catherine Schuster, Kazuaki Chayama, Patrick Pessaux, Kenneth K Tanabe, Yujin Hoshida, Mirjam B Zeisel, François HT Duong, Bryan C Fuchs, Thomas F Baumert

doi: 10.1136/gutjnl-2019-318918
GI cancer
Organoid cultures of early-onset colorectal cancers reveal distinct and rare genetic profiles

Helen H N Yan, Hoi Cheong Siu, Siu Lun Ho, Sarah S K Yue, Yang Gao, Wai Yin Tsui, Dessy Chan, April S Chan, Jason W H Wong, Alice H Y Man, Bernard C H Lee, Annie S Y Chan, Anthony K W Chan, Ho Sang Hui, Arthur K L Cheung, Wai Lun Law, Oswens S H Lo, Siu Tsan Yuen, Hans Clevers, Suet Yi Leung

doi: 10.1136/gutjnl-2019-320019
Endoscopy News
Transmucosal diverticular myotomy for the treatment of oesophageal diverticula associated with spastic motility disorders

Mayenaaz Sidhu, David J Tate, Michael J Bourke

doi: 10.1136/gutjnl-2019-320481
Hepatology
Population impact of direct-acting antiviral treatment on new presentations of hepatitis C-related decompensated cirrhosis: a national record-linkage study

Sharon J Hutchinson, Heather Valerio, Scott A McDonald, Alan Yeung, Kevin Pollock, Shanley Smith, Stephen Barclay, John F Dillon, Raymond Fox, Peter Bramley, Andrew Fraser, Nicholas Kennedy, Rory N Gunson, Kate Templeton, Hamish Innes, Allan McLeod, Amanda Weir, Peter C Hayes, David Goldberg

doi: 10.1136/gutjnl-2019-320007

March 24, 2020

Gastroduodenal
Epidemiological, clinical and virological characteristics of 74 cases of coronavirus-infected disease 2019 (COVID-19) with gastrointestinal symptoms

Xi Jin, Jiang-Shan Lian, Jian-Hua Hu, Jianguo Gao, Lin Zheng, Yi-Min Zhang, Shao-Rui Hao, Hong-Yu Jia, Huan Cai, Xiao-Li Zhang, Guo-Dong Yu, Kai-Jin Xu, Xiao-Yan Wang, Jue-Qing Gu, Shan-Yan Zhang, Chan-Yuan Ye, Ci-Liang Jin, Ying-Feng Lu, Xia Yu, Xiao-Peng Yu, Jian-Rong Huang, Kang-Li Xu, Qin Ni, Cheng-Bo Yu, Biao Zhu, Yong-Tao Li, Jun Liu, Hong Zhao, Xuan Zhang, Liang Yu, Yong-Zheng Guo, Jun-Wei Su, Jing-Jing Tao, Guan-Jing Lang, Xiao-Xin Wu, Wen-Rui Wu, Ting-Ting Qv, Dai-Rong Xiang, Ping Yi, Ding Shi, Yanfei Chen, Yue Ren, Yun-Qing Qiu, Lan-Juan Li, Jifang Sheng, Yida Yang

doi: 10.1136/gutjnl-2020-320926
Endoscopy
Adenoma detection by Endocuff-assisted versus standard colonoscopy in routine practice: a cluster-randomised crossover trial

David Karsenti, Gaelle Tharsis, Bastien Perrot, Philippe Cattan, Gilles Tordjman, Franck Venezia, Elie Zrihen, Dominique Gillot, Agnes Gillet, Charles Hagege, Joelle Samama, Isabelle Etienney, Jean-Philippe Lab, Bernard Guigui, Jacqueline Zago, Bouchra Benkessou, Pascal Burtin, Maryan Cavicchi

doi: 10.1136/gutjnl-2019-319565
PostScript
Pharmacological treatment of opioid-induced constipation: moving ahead to new targets

Fabio Lugoboni, Federico Vignoni, Stefano Tamburin Gruppo InterSERT di Collaborazione Scientifica (GICS)

doi: 10.1136/gutjnl-2020-320602

March 23, 2020

Nutrition
Bile acid composition regulates GPR119-dependent intestinal lipid sensing and food intake regulation in mice

Sei Higuchi, Tiara R Ahmad, Donovan A Argueta, Pedro A Perez, Chen Zhao, Gary J Schwartz, Nicholas V DiPatrizio, Rebecca A Haeusler

doi: 10.1136/gutjnl-2019-319693
Helicobacter pylori
Helicobacter pylori eradication therapy to prevent gastric cancer: systematic review and meta-analysis

Alexander Charles Ford, Yuhong Yuan, Paul Moayyedi

doi: 10.1136/gutjnl-2020-320839
Commentary
Prevention of endpoints in primary biliary cholangitis with ursodeoxycholic acid: quantifying the benefit

Jörn M Schattenberg

doi: 10.1136/gutjnl-2019-320355
Nutrition
Intestinal gluconeogenesis prevents obesity-linked liver steatosis and non-alcoholic fatty liver disease

Justine Vily-Petit, Maud Soty-Roca, Marine Silva, Margaux Raffin, Amandine Gautier-Stein, Fabienne Rajas, Gilles Mithieux

doi: 10.1136/gutjnl-2019-319745

March 22, 2020

PostScript
SARS-CoV-2 induced diarrhoea as onset symptom in patient with COVID-19
Free

Y Song, P Liu, X L Shi, Y L Chu, J Zhang, J Xia, X Z Gao, T Qu, M Y Wang

doi: 10.1136/gutjnl-2020-320891

March 20, 2020

PostScript
COVID-19 in gastroenterology: a clinical perspective
Free

John Ong, Barnaby Edward Young, Sharon Ong

doi: 10.1136/gutjnl-2020-321051

March 16, 2020

Nutrition
Treatment of severe acute malnutrition with oat or standard ready-to-use therapeutic food: a triple-blind, randomised controlled clinical trial

David Taylor Hendrixson, Claire Godbout, Alyssa Los, Meghan Callaghan-Gillespie, Melody Mui, Donna Wegner, Taylor Bryant, Aminata Koroma, Mark J Manary

doi: 10.1136/gutjnl-2020-320769
Editor’s quiz: GI snapshot
Aggressive case of early onset gastric cancer; identifying the knowledge gap

Jennifer M Kolb, Stephen Leong, Lindsey M Westbrook, Swati G Patel

doi: 10.1136/gutjnl-2019-320453
Leading article
Challenges and opportunities for IBD drug development: from early stage to regulatory approval

Silvio Danese, Elmer Schabel, Mark Andrew Ainsworth, Laurent Peyrin-Biroulet

doi: 10.1136/gutjnl-2019-320542

March 13, 2020

Commentary
Mediterranean diet, gut microbiota and health: when age and calories do not add up!

Patrice D Cani, Matthias Van Hul

doi: 10.1136/gutjnl-2020-320781
Gut microbiota
A purified membrane protein from Akkermansia muciniphila or the pasteurised bacterium blunts colitis associated tumourigenesis by modulation of CD8⁺ T cells in mice

Lijuan Wang, Lei Tang, Yiming Feng, Suying Zhao, Mei Han, Chuan Zhang, Gehui Yuan, Jun Zhu, Shuyuan Cao, Qian Wu, Lei Li, Zhan Zhang

doi: 10.1136/gutjnl-2019-320105
Commentary
Changing TACTICS in intermediate HCC: TACE plus sorafenib

Pompilia Radu, Jean-François Dufour

doi: 10.1136/gutjnl-2020-320692

March 12, 2020

Gut microbiota
Faecal virome transplantation decreases symptoms of type 2 diabetes and obesity in a murine model

Torben Sølbeck Rasmussen, Caroline Märta Junker Mentzel, Witold Kot, Josué Leonardo Castro-Mejía, Simone Zuffa, Jonathan Richard Swann, Lars Hestbjerg Hansen, Finn Kvist Vogensen, Axel Kornerup Hansen, Dennis Sandris Nielsen

doi: 10.1136/gutjnl-2019-320005
Endoscopy
Endosonography-guided gallbladder drainage versus percutaneous cholecystostomy in very high-risk surgical patients with acute cholecystitis: an international randomised multicentre controlled superiority trial (DRAC 1)

Anthony Y B Teoh, Masayuki Kitano, Takao Itoi, Manuel Pérez-Miranda, Takeshi Ogura, Shannon Melissa Chan, Carlos Serna-Higuera, Shunsuke Omoto, Raul Torres-Yuste, Takayoshi Tsuichiya, Ka Tak Wong, Chi-Ho Leung, Philip Wai Yan Chiu, Enders Kwok Wai Ng, James Yun Wong Lau

doi: 10.1136/gutjnl-2019-319996

March 10, 2020

Helicobacter pylori
Seven-day vonoprazan and low-dose amoxicillin dual therapy as first-line Helicobacter pylori treatment: a multicentre randomised trial in Japan

Sho Suzuki, Takuji Gotoda, Chika Kusano, Hisatomo Ikehara, Ryoji Ichijima, Motoki Ohyauchi, Hirotaka Ito, Masashi Kawamura, Yohei Ogata, Masahiko Ohtaka, Moriyasu Nakahara, Koichi Kawabe

doi: 10.1136/gutjnl-2019-319954

March 05, 2020

PostScript
Characterisation of innate lymphoid cell subsets infiltrating colorectal carcinoma

Paolo Carrega, Paola Orecchia, Linda Quatrini, Nicola Tumino, Roberta Venè, Roberto Benelli, Alessandro Poggi, Stefano Scabini, Maria Cristina Mingari, Lorenzo Moretta, Paola Vacca

doi: 10.1136/gutjnl-2020-320908
PostScript
Microbiome alterations in IBS

Ian B Jeffery, Eileen O'Herlihy, Fergus Shanahan, Paul W O' Toole

doi: 10.1136/gutjnl-2020-320919
GI cancer
Substantial and sustained improvement of serrated polyp detection after a simple educational intervention: results from a prospective controlled trial

Arne G C Bleijenberg, Monique E van Leerdam, Marloes Bargeman, Jan Jacob Koornstra, Yasmijn J van Herwaarden, Manon CW Spaander, Silvia Sanduleanu, Barbara A J Bastiaansen, Erik J Schoon, Niels van Lelyveld, Evelien Dekker, Joep E G IJspeert

doi: 10.1136/gutjnl-2019-319804

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