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BMJ Journals More

Online First

April 12, 2021

Letter
Long-term exposure to fine particulate matter and non-alcoholic fatty liver disease: a prospective cohort study

Shengzhi Sun, Qingqing Yang, Qingxin Zhou, Wangnan Cao, Siwang Yu, Siyan Zhan, Feng Sun

doi: 10.1136/gutjnl-2021-324364
Pancreas
A GATA6-centred gene regulatory network involving HNFs and ΔNp63 controls plasticity and immune escape in pancreatic cancer

Bernhard Kloesch, Vivien Ionasz, Sumit Paliwal, Natascha Hruschka, Jaime Martinez de Villarreal, Rupert Öllinger, Sebastian Mueller, Hans Peter Dienes, Martin Schindl, Elisabeth S Gruber, Judith Stift, Dietmar Herndler-Brandstetter, Gwen A Lomberk, Barbara Seidler, Dieter Saur, Roland Rad, Raul A Urrutia, Francisco X Real, Paola Martinelli

doi: 10.1136/gutjnl-2020-321397

April 09, 2021

Gut microbiota
Alterations in the human oral and gut microbiomes and lipidomics in COVID-19

Zhigang Ren, Haiyu Wang, Guangying Cui, Haifeng Lu, Ling Wang, Hong Luo, Xinhua Chen, Hongyan Ren, Ranran Sun, Wenli Liu, Xiaorui Liu, Chao Liu, Ang Li, Xuemei Wang, Benchen Rao, Chengyu Yuan, Hua Zhang, Jiarui Sun, Xiaolong Chen, Bingjie Li, Chuansong Hu, Zhongwen Wu, Zujiang Yu, Quancheng Kan, Lanjuan Li

doi: 10.1136/gutjnl-2020-323826
GI cancer
Activation of the GPR35 pathway drives angiogenesis in the tumour microenvironment

Ester Pagano, Joshua E Elias, Georg Schneditz, Svetlana Saveljeva, Lorraine M Holland, Francesca Borrelli, Tom H Karlsen, Arthur Kaser, Nicole C Kaneider

doi: 10.1136/gutjnl-2020-323363
Inflammatory bowel disease
Predicting endoscopic remission in Crohn’s disease by the modified multiplier SES-CD (MM-SES-CD)

Neeraj Narula, Emily C L Wong, Jean-Frederic Colombel, William J Sandborn, John Kenneth Marshall, Marco Daperno, Walter Reinisch, Parambir S Dulai

doi: 10.1136/gutjnl-2020-323799
Helicobacter pylori
Helicobacter pylori resistance to antibiotics in Europe in 2018 and its relationship to antibiotic consumption in the community

Francis Megraud, Robin Bruyndonckx, Samuel Coenen, Linda Wittkop, Te-Din Huang, Martin Hoebeke, Lucie Bénéjat, Philippe Lehours, Herman Goossens, Youri Glupczynski The European Helicobacter pylori Antimicrobial Susceptibility Testing Working Group

doi: 10.1136/gutjnl-2021-324032

April 08, 2021

Letter
Colonoscopic polypectomy in patients on anticoagulation: time to embrace the cold revolution?

Nicholas McDonald, Saurabh Chandan, Mohammad Bilal

doi: 10.1136/gutjnl-2021-324790
Letter
Six-month follow-up of gut microbiota richness in patients with COVID-19

Yanfei Chen, Silan Gu, Yunbo Chen, Haifeng Lu, Ding Shi, Jing Guo, Wen-Rui Wu, Ya Yang, Yongtao Li, Kai-Jin Xu, Cheng Ding, Rui Luo, Chenjie Huang, Ling Yu, Min Xu, Ping Yi, Jun Liu, Jing-jing Tao, Hua Zhang, Longxian Lv, Baohong Wang, Jifang Sheng, Lanjuan Li

doi: 10.1136/gutjnl-2021-324090
Hepatology
HCV genome-wide analysis for development of efficient culture systems and unravelling of antiviral resistance in genotype 4

Long V. Pham, Martin Schou Pedersen, Ulrik Fahnøe, Carlota Fernandez-Antunez, Daryl Humes, Kristian Schønning, Santseharay Ramirez, Jens Bukh

doi: 10.1136/gutjnl-2020-323585
Letter
Appendoscopy in patients with serrated polyposis syndrome

Rachel Hallit, Maximilien Barret, Arthur Belle, Einas Abou Ali, Marion Dhooge, Romain Coriat, Stanislas Chaussade

doi: 10.1136/gutjnl-2021-324679

April 07, 2021

Pancreas
Exosome-delivered CD44v6/C1QBP complex drives pancreatic cancer liver metastasis by promoting fibrotic liver microenvironment

Zhibo Xie, Ya Gao, Chiakang Ho, Lequn Li, Chen Jin, Xiaoyi Wang, Caifeng Zou, Yishen Mao, Xiaobo Wang, Qingfeng Li, Deliang Fu, Yi-Fan Zhang

doi: 10.1136/gutjnl-2020-323014
Letter
Letter to editor: piecemeal cold snare polypectomy versus conventional endoscopic mucosal resection for large sessile serrated lesions

Haiying Guan, Chunyan Zeng, Youxiang Chen

doi: 10.1136/gutjnl-2021-324531

April 05, 2021

Pancreas
Long-term yield of pancreatic cancer surveillance in high-risk individuals

Kasper A Overbeek, Iris J M Levink, Brechtje D M Koopmann, Femme Harinck, Ingrid C A W Konings, Margreet G E M Ausems, Anja Wagner, Paul Fockens, Casper H van Eijck, Bas Groot Koerkamp, Olivier R C Busch, Marc G Besselink, Barbara A J Bastiaansen, Lydi M J W van Driel, Nicole S Erler, Frank P Vleggaar, Jan-Werner Poley, Djuna L Cahen, Jeanin E van Hooft, Marco J Bruno on behalf of the Dutch Familial Pancreatic Cancer Surveillance Study Group

doi: 10.1136/gutjnl-2020-323611

April 02, 2021

Gut microbiota
Long-term dietary patterns are associated with pro-inflammatory and anti-inflammatory features of the gut microbiome

Laura A Bolte, Arnau Vich Vila, Floris Imhann, Valerie Collij, Ranko Gacesa, Vera Peters, Cisca Wijmenga, Alexander Kurilshikov, Marjo J E Campmans-Kuijpers, Jingyuan Fu, Gerard Dijkstra, Alexandra Zhernakova, Rinse K Weersma

doi: 10.1136/gutjnl-2020-322670
Commentary
Relative risk rather than absolute risk reduction should be preferred to sensitise the public to preventive actions
Free

Nicolas Chapelle, Myriam Martel, Alan N Barkun, Marc Bardou

doi: 10.1136/gutjnl-2021-324689

March 31, 2021

Leading article
Drug development for ulcerative proctitis: current concepts

Bénédicte Caron, William J Sandborn, Stefan Schreiber, Remo Panaccione, Silvio Danese, Laurent Peyrin-Biroulet

doi: 10.1136/gutjnl-2021-324108
Letter
Hepatic hydrothorax in the management of cirrhosis

Karl Jackson, Richard Davidson, Avinash Aujayeb

doi: 10.1136/gutjnl-2021-324698
GI cancer
Non-compliance with colonoscopy after a positive faecal immunochemical test doubles the risk of dying from colorectal cancer

Manuel Zorzi, Jessica Battagello, Kevin Selby, Giulia Capodaglio, Susanna Baracco, Silvia Rizzato, Enrico Chinellato, Stefano Guzzinati, Massimo Rugge

doi: 10.1136/gutjnl-2020-322192
Letter
Enhanced donor screening for faecal microbial transplantation during COVID-19

Seema Nair Parvathy, John G Lenehan, Ricardo Fernandes, Susan M Poutanen, Susy Hota, Saman Maleki Vareki, Michael Silverman

doi: 10.1136/gutjnl-2021-324593
Hepatology
Long-term safety of infants from mothers with chronic hepatitis B treated with tenofovir disoproxil in China

Calvin Q. Pan, Erhei Dai, Zhongping Duan, Guorong Han, Wenjing Zhao, Yuming Wang, Huaihong Zhang, Baoshen Zhu, Hongxiu Jiang, Shuqin Zhang, Xiaohu Zhang, Huaibin Zou, Xiuli Chen, Yu Chen

doi: 10.1136/gutjnl-2020-322719
Upper GI cancer
Pan-ERBB kinase inhibition augments CDK4/6 inhibitor efficacy in oesophageal squamous cell carcinoma

Jin Zhou, Zhong Wu, Zhouwei Zhang, Louisa Goss, James McFarland, Ankur Nagaraja, Yingtian Xie, Shengqing Gu, Ke Peng, Yong Zeng, Xiaoyang Zhang, Henry Long, Hiroshi Nakagawa, Anil Rustgi, J Alan Diehl, Matthew Meyerson, Kwok-Kin Wong, Adam Bass

doi: 10.1136/gutjnl-2020-323276

March 30, 2021

Inflammatory bowel disease
Agonist that activates the µ-opioid receptor in acidified microenvironments inhibits colitis pain without side effects

Nestor Nivardo Jiménez-Vargas, Yang Yu, Dane D Jensen, Diana Daeun Bok, Matthew Wisdom, Rocco Latorre, Cintya Lopez, Josue O Jaramillo-Polanco, Claudius Degro, Mabel Guzman-Rodriguez, Quentin Tsang, Zachary Snow, Brian L Schmidt, David E Reed, Alan Edward Lomax, Kara Gross Margolis, Christoph Stein, Nigel W Bunnett, Stephen J Vanner

doi: 10.1136/gutjnl-2021-324070
Commentary
Selecting optimal patients with gastroparesis for G-POEM procedure

Ting Zheng, Michael Camilleri

doi: 10.1136/gutjnl-2021-324631
GI cancer
Targeting cancer-associated fibroblast-secreted WNT2 restores dendritic cell-mediated antitumour immunity

Tu-Xiong Huang, Xiang-Yu Tan, Hui-Si Huang, Yu-Ting Li, Bei-Lei Liu, Kai-Sheng Liu, Xinchun Chen, Zhe Chen, Xin-Yuan Guan, Chang Zou, Li Fu

doi: 10.1136/gutjnl-2020-322924
Commentary
Several faces of refractory coeliac disease type 2

Joseph A Murray

doi: 10.1136/gutjnl-2021-324251
Letter
If pneumatic dilation is not enough efficient for post fundoplication dysphagia, is Per Oral Endoscopic Myotomy a good answer to manage it?

Antoine Debourdeau, Véronique Vitton, Marc A Barthet, Jean-Michel Gonzalez

doi: 10.1136/gutjnl-2021-324238
GI cancer
Loss of ARID1A activates mTOR signaling and SOX9 in gastric adenocarcinoma—rationale for targeting ARID1A deficiency

Xiaochuan Dong, Shumei Song, Yuan Li, Yibo Fan, Lulu Wang, Ruiping Wang, Longfei Huo, Ailing Scott, Yan Xu, Melissa Pool Pizzi, Lang Ma, Ying Wang, Jiangkang Jin, Wei Zhao, Xiaodan Yao, Randy L Johnson, Linghua Wang, Zhenning Wang, Guang Peng, Jaffer A Ajani

doi: 10.1136/gutjnl-2020-322660
Commentary
End of the story: direct-acting antiviral agents are not associated with recurrence of hepatocellular carcinoma

Ruben Hernaez, Robert Thimme

doi: 10.1136/gutjnl-2021-324288
Gut microbiota
Microbiota engraftment after faecal microbiota transplantation in obese subjects with type 2 diabetes: a 24-week, double-blind, randomised controlled trial

Siew C Ng, Zhilu Xu, Joyce Wing Yan Mak, Keli Yang, Qin Liu, Tao Zuo, Whitney Tang, Louis Lau, Rashid N Lui, Sunny H Wong, Yee Kit Tse, Amy Y L Li, Kitty Cheung, Jessica Y L Ching, Vincent W S Wong, Alice P S Kong, Ronald C W Ma, Elaine Y K Chow, Simon K H Wong, Ivan Chak Hang Ho, Paul K S Chan, Francis K L Chan

doi: 10.1136/gutjnl-2020-323617

March 25, 2021

Letter
Acute-on-chronic liver failure in East Asia: an underestimated issue with limited data

Zhujun Cao, Qing Xie

doi: 10.1136/gutjnl-2021-324564
Endoscopy news
Radiology-guided percutaneous approach is superior to EUS for performing liver biopsies

Ji Young Bang, Thomas J Ward, Shady Guirguis, Konrad Krall, Francisco Contreras, Nirag Jhala, Udayakumar Navaneethan, Robert H Hawes, Shyam Varadarajulu

doi: 10.1136/gutjnl-2021-324495

March 24, 2021

Inflammatory bowel disease
Risk factors for SARS-CoV-2 infection and course of COVID-19 disease in patients with IBD in the Veterans Affair Healthcare System

Nabeel Khan, Nadim Mahmud, Chinmay Trivedi, Walter Reinisch, James D Lewis

doi: 10.1136/gutjnl-2021-324356
Endoscopy news
COVID-19 transmission following outpatient endoscopy during pandemic acceleration phase involving SARS-CoV-2 VOC 202012/01 variant in UK
Free

Bu'Hussain Hayee, The SCOTS II Project group, Pradeep Bhandari, Colin J Rees, Ian Penman

doi: 10.1136/gutjnl-2021-324354

March 23, 2021

Commentary
Endoscopic submucosal dissection and potential cancer dissemination

Kenneth K Wang

doi: 10.1136/gutjnl-2020-323925

March 22, 2021

Letter
Colon capsule endoscopy: the evidence is piling up

George Koulaouzidis, Alexander Robertson, Hagen Wenzek, Anastasios Koulaouzidis

doi: 10.1136/gutjnl-2021-324246
Letter
CT colonography remains an important test for colorectal cancer

Nicholas Ewin Burr, Andrew Plumb, Ruchit Sood, Bjorn Rembacken, Damian J M Tolan

doi: 10.1136/gutjnl-2021-324399
Gut microbiota
Blue poo: impact of gut transit time on the gut microbiome using a novel marker

Francesco Asnicar, Emily R Leeming, Eirini Dimidi, Mohsen Mazidi, Paul W Franks, Haya Al Khatib, Ana M Valdes, Richard Davies, Elco Bakker, Lucy Francis, Andrew Chan, Rachel Gibson, George Hadjigeorgiou, Jonathan Wolf, Timothy D Spector, Nicola Segata, Sarah E Berry

doi: 10.1136/gutjnl-2020-323877
Letter
Composition, diversity and potential utility of intervention-naïve pancreatic cancer intratumoral microbiome signature profiling via endoscopic ultrasound

Ferga C Gleeson, Patricio Jeraldo, Michael J Levy, Stephen J Murphy, Helena Mendes-Soares, Giannoula Karagouga, Alexa F Mccune, Ana Garcia Garcia Deparedes, Benjamin R Kipp, Stephanie D Song, Sahil Khanna, Darrell S Pardi, Nicholas Chia

doi: 10.1136/gutjnl-2021-324031
Oesophagus
Long-term outcomes after endoscopic treatment for Barrett’s neoplasia with radiofrequency ablation ± endoscopic resection: results from the national Dutch database in a 10-year period

Sanne van Munster, Esther Nieuwenhuis, Bas L A M Weusten, Lorenza Alvarez Herrero, Auke Bogte, Alaa Alkhalaf, B E Schenk, Erik J Schoon, Wouter Curvers, Arjun D Koch, Steffi Elisabeth Maria van de Ven, Pieter Jan Floris de Jonge, Tjon J Tang, Wouter B Nagengast, Frans T M Peters, Jessie Westerhof, Martin H M G Houben, Jacques JGHM Bergman, Roos E Pouw Dutch Barrett Expert Centers

doi: 10.1136/gutjnl-2020-322615

March 19, 2021

Endoscopy
Gastric per-oral endoscopic myotomy (G-POEM) for refractory gastroparesis: results from an international prospective trial

Kia Vosoughi, Yervant Ichkhanian, Petros Benias, Larry Miller, A Aziz Aadam, Joseph R Triggs, Ryan Law, William Hasler, Nicole Bowers, Dalton Chaves, Alberto M Ponte-Neto, Peter Draganov, Dennis Yang, Maan El Halabi, Omid Sanaei, Olaya Isabella Brewer Gutierrez, Robert Stephen Bulat, John Pandolfino, Mouen Khashab

doi: 10.1136/gutjnl-2020-322756
Hepatology
Hepatocellular carcinoma recurrence after direct-acting antiviral therapy: an individual patient data meta-analysis

Victor Sapena, Marco Enea, Ferran Torres, Ciro Celsa, Jose Rios, Giacomo Emanuele Maria Rizzo, Pierre Nahon, Zoe Mariño, Ryosuke Tateishi, Tatsuya Minami, Angelo Sangiovanni, Xavier Forns, Hidenori Toyoda, Stefano Brillanti, Fabio Conti, Elisabetta Degasperi, Ming-Lung Yu, Pei-Chien Tsai, Kevin Jean, Mohamed El Kassas, Hend Ibrahim Shousha, Ashraf Omar, Claudio Zavaglia, Hiroko Nagata, Mina Nakagawa, Yasuhiro Asahina, Amit G Singal, Caitlin Murphy, Mohamed Kohla, Chiara Masetti, Jean-François Dufour, Nicolas Merchante, Luisa Cavalletto, liliana LC chemello, Stanislas POL, Javier Crespo, Jose Luis Calleja, Rosanna Villani, Gaetano Serviddio, Alberto Zanetto, Sarah Shalaby, Francesco Paolo Russo, Rob Bielen, Franco Trevisani, Calogero Cammà, Jordi Bruix, Giuseppe Cabibbo, Maria Reig

doi: 10.1136/gutjnl-2020-323663

March 18, 2021

Letter
Role of the gut microbiome in mediating lactose intolerance symptoms

M F Brandao Gois, Trishla Sinha, Johanne E Spreckels, Arnau Vich Vila, Laura A Bolte, Rinse K Weersma, Cisca Wijmenga, Jingyuan Fu, Alexandra Zhernakova, Alexander Kurilshikov

doi: 10.1136/gutjnl-2020-323911
Endoscopy
Linked Colour imaging for the detection of polyps in patients with Lynch syndrome: a multicentre, parallel randomised controlled trial

Britt B S L Houwen, Yark Hazewinkel, María Pellisé, Liseth Rivero-Sánchez, Francesc Balaguer, Raf Bisschops, Sabine Tejpar, Alessandro Repici, D Ramsoekh, Maarten A J M Jacobs, Ramon-Michel M Schreuder, Michal Filip Kaminski, Maria Rupinska, Pradeep Bhandari, Martijn G H van Oijen, Lianne Koens, Barbara A J Bastiaansen, Kristien M Tytgat, Paul Fockens, Jasper L A Vleugels, E Dekker

doi: 10.1136/gutjnl-2020-323132

March 17, 2021

Letter
Utility of mismatch repair protein expression screening via an endoscopic ultrasound assessment of treatment-naive pancreas ductal adenocarcinoma

Ana Garcia Garcia de Paredes, Rondell P Graham, Michael J Levy, Robert R McWilliams, Elizabeth Rajan, Lizhi Zhang, Ferga C Gleeson

doi: 10.1136/gutjnl-2021-324460

March 16, 2021

Hepatology
Placental growth factor promotes tumour desmoplasia and treatment resistance in intrahepatic cholangiocarcinoma

Shuichi Aoki, Koetsu Inoue, Sebastian Klein, Stefan Halvorsen, Jiang Chen, Aya Matsui, Mohammad R Nikmaneshi, Shuji Kitahara, Tai Hato, Xianfeng Chen, Kazumichi Kawakubo, Hadi T Nia, Ivy Chen, Daniel H Schanne, Emilie Mamessier, Kohei Shigeta, Hiroto Kikuchi, Rakesh R Ramjiawan, Tyge CE Schmidt, Masaaki Iwasaki, Thomas Yau, Theodore S Hong, Alexander Quaas, Patrick S Plum, Simona Dima, Irinel Popescu, Nabeel Bardeesy, Lance L Munn, Mitesh J Borad, Slim Sassi, Rakesh K. Jain, Andrew X Zhu, Dan G Duda

doi: 10.1136/gutjnl-2020-322493

March 15, 2021

Commentary
Infliximab at diagnosis: moving towards personalisation in paediatric inflammatory bowel disease

James J Ashton, Sarah Ennis, R Mark Beattie

doi: 10.1136/gutjnl-2021-324214
Gut microbiota
Gut microbiota modulates COPD pathogenesis: role of anti-inflammatory Parabacteroides goldsteinii lipopolysaccharide

Hsin-Chih Lai, Tzu-Lung Lin, Ting-Wen Chen, Yu-Lun Kuo, Chih-Jung Chang, Tsung-Ru Wu, Ching-Chung Shu, Ying-Huang Tsai, Simon Swift, Chia-Chen Lu

doi: 10.1136/gutjnl-2020-322599

March 12, 2021

Hepatology
Long-term serological, virological and histological responses to RNA inhibition by ARC-520 in Chinese chronic hepatitis B patients on entecavir treatment

Man-Fung Yuen, Danny Ka-Ho Wong, Thomas Schluep, Ching-Lung Lai, Carlo Ferrari, Stephen Locarnini, Regina Cheuk-Lam Lo, Robert G Gish, James Hamilton, Christine I Wooddell, Lung Yi Mak, Bruce D Given

doi: 10.1136/gutjnl-2020-323445
Commentary
NAFLD in lean individuals: not a benign disease

Sven Francque, Vincent Wai-Sun Wong

doi: 10.1136/gutjnl-2021-324162
Letter
Large volume paracentesis: to do or where to do?

Lucia Macken, Naaventhan Palaniyappan, Sumita Verma, Guruprasad Aithal

doi: 10.1136/gutjnl-2021-324249

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