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BMJ Journals More

Online First

June 21, 2021

Hepatology
Liver function test abnormalities at hospital admission are associated with severe course of SARS-CoV-2 infection: a prospective cohort study

Sabine Weber, Johannes C Hellmuth, Clemens Scherer, Maximilian Muenchhoff, Julia Mayerle, Alexander L Gerbes

doi: 10.1136/gutjnl-2020-323800

June 18, 2021

Recent advances in basic science
Calprotectin: from biomarker to biological function

Almina Jukic, Latifa Bakiri, Erwin F. Wagner, Herbert Tilg, Timon E. Adolph

doi: 10.1136/gutjnl-2021-324855
Commentary
Pancreatic cancer surveillance and its ongoing challenges: is it time to refine our eligibility criteria?

Thomas P Potjer

doi: 10.1136/gutjnl-2021-324739
Editor’s quiz: GI snapshot
Should you trust the radiologist?

Sun Mi Ha, Donal Sheehan, Ahmed Shalabi, Malcolm A West, Rajapandian Ilangovan, Morgan Moorghen, John T Jenkins, Siwan Thomas-Gibson

doi: 10.1136/gutjnl-2021-325129

June 17, 2021

Neurogastroenterology
Decoy bypass for appetite suppression in obese adults: role of synergistic nutrient sensing receptors GPR84 and FFAR4 on colonic endocrine cells

Madusha Peiris, Rubina Aktar, David Reed, Vincent Cibert-Goton, Ausra Zdanaviciene, Writaja Halder, Adam Robinow, Simon Corke, Harween Dogra, Charles H Knowles, Ashley Blackshaw

doi: 10.1136/gutjnl-2020-323219
Letter
Acute-on-chronic liver failure (ACLF) precipitated by severe alcoholic hepatitis: another collateral damage of the COVID-19 pandemic?

Esra Görgülü, Wenyi Gu, Jonel Trebicka, Victoria Therese Mücke, Marcus Maximilian Muecke, Mireen Friedrich-Rust, Joerg Bojunga, Stefan Zeuzem, Fabian Finkelmeier, Kai-Henrik Peiffer

doi: 10.1136/gutjnl-2021-325278

June 16, 2021

Letter
Guts UK 50 years old: onwards and upwards

Julie Harrington, John McLaughlin, Jonathan M Rhodes

doi: 10.1136/gutjnl-2021-325324

June 15, 2021

Letter
Duality of the association between COVID-19 and acute pancreatitis
Free

Xiu-He Lv, Kai Deng, Jin-Lin Yang

doi: 10.1136/gutjnl-2021-325221

June 14, 2021

Letter
Residual SARS-CoV-2 viral antigens detected in GI and hepatic tissues from five recovered patients with COVID-19
Free

Chun Chau Lawrence Cheung, Denise Goh, Xinru Lim, Tracy Zhijun Tien, Jeffrey Chun Tatt Lim, Justina Nadia Lee, Benedict Tan, Zhi En Amos Tay, Wei Yee Wan, Eileen Xueqin Chen, Sanjna Nilesh Nerurkar, Shihleone Loong, Peng Chung Cheow, Chung Yip Chan, Ye Xin Koh, Thuan Tong Tan, Shirin Kalimuddin, Wai Meng David Tai, Jia Lin Ng, Jenny Guek-Hong Low, Joe Yeong, Kiat Hon Lim

doi: 10.1136/gutjnl-2021-324280
Gut microbiota
Host and gut microbial tryptophan metabolism and type 2 diabetes: an integrative analysis of host genetics, diet, gut microbiome and circulating metabolites in cohort studies

Qibin Qi, Jun Li, Bing Yu, Jee-Young Moon, Jin C Chai, Jordi Merino, Jie Hu, Miguel Ruiz-Canela, Casey Rebholz, Zheng Wang, Mykhaylo Usyk, Guo-Chong Chen, Bianca C Porneala, Wenshuang Wang, Ngoc Quynh Nguyen, Elena V Feofanova, Megan L Grove, Thomas J Wang, Robert E Gerszten, Josée Dupuis, Jordi Salas-Salvadó, Wei Bao, David L Perkins, Martha L Daviglus, Bharat Thyagarajan, Jianwen Cai, Tao Wang, JoAnn E Manson, Miguel A Martínez-González, Elizabeth Selvin, Kathryn M Rexrode, Clary B Clish, Frank B Hu, James B Meigs, Rob Knight, Robert D Burk, Eric Boerwinkle, Robert C Kaplan

doi: 10.1136/gutjnl-2021-324053
Hepatology
Diagnostic accuracy of non-invasive tests for advanced fibrosis in patients with NAFLD: an individual patient data meta-analysis

Ferenc Emil Mózes, Jenny A Lee, Emmanuel Anandraj Selvaraj, Arjun Narayan Ajmer Jayaswal, Michael Trauner, Jerome Boursier, Céline Fournier, Katharina Staufer, Rudolf E Stauber, Elisabetta Bugianesi, Ramy Younes, Silvia Gaia, Monica Lupșor-Platon, Salvatore Petta, Toshihide Shima, Takeshi Okanoue, Sanjiv Mahadeva, Wah-Kheong Chan, Peter J Eddowes, Gideon M Hirschfield, Philip Noel Newsome, Vincent Wai-Sun Wong, Victor de Ledinghen, Jiangao Fan, Feng Shen, Jeremy F Cobbold, Yoshio Sumida, Akira Okajima, Jörn M Schattenberg, Christian Labenz, Won Kim, Myoung Seok Lee, Johannes Wiegand, Thomas Karlas, Yusuf Yılmaz, Guruprasad Padur Aithal, Naaventhan Palaniyappan, Christophe Cassinotto, Sandeep Aggarwal, Harshit Garg, Geraldine J Ooi, Atsushi Nakajima, Masato Yoneda, Marianne Ziol, Nathalie Barget, Andreas Geier, Theresa Tuthill, M. Julia Brosnan, Quentin Mark Anstee, Stefan Neubauer, Stephen A. Harrison, Patrick M Bossuyt, Michael Pavlides the LITMUS Investigators

doi: 10.1136/gutjnl-2021-324243
Letter
Diabetes is the strongest risk factor of hepatic fibrosis in lean patients with non-alcoholic fatty liver disease

Huiyul Park, Eileen L Yoon, Seon Cho, Dae Won Jun, Eun-Hee Nah

doi: 10.1136/gutjnl-2021-325102

June 11, 2021

Letter
SARS-COV-2 in endoscopy: still a long way to go
Free

Maria Valeria Matteo, Ivo Boškoski, Guido Costamagna

doi: 10.1136/gutjnl-2021-325052

June 09, 2021

GI cancer
Faecal immunochemical tests safely enhance rational use of resources during the assessment of suspected symptomatic colorectal cancer in primary care: systematic review and meta-analysis

Noel Pin-Vieito, Coral Tejido-Sandoval, Natalia de Vicente-Bielza, Cristina Sánchez-Gómez, Joaquín Cubiella

doi: 10.1136/gutjnl-2021-324856

June 08, 2021

Gut microbiota
Dysosmobacter welbionis is a newly isolated human commensal bacterium preventing diet-induced obesity and metabolic disorders in mice

Tiphaine Le Roy, Emilie Moens de Hase, Matthias Van Hul, Adrien Paquot, Rudy Pelicaen, Marion Régnier, Clara Depommier, Céline Druart, Amandine Everard, Dominique Maiter, Nathalie M Delzenne, Laure B Bindels, Marie de Barsy, Audrey Loumaye, Michel P Hermans, Jean-Paul Thissen, Sara Vieira-Silva, Gwen Falony, Jeroen Raes, Giulio G Muccioli, Patrice D Cani

doi: 10.1136/gutjnl-2020-323778
Recent advances in clinical practice
Understanding the role of the gut in undernutrition: what can technology tell us?

Alex J Thompson, Claire D Bourke, Ruairi C Robertson, Nirupama Shivakumar, Christine A Edwards, Tom Preston, Elaine Holmes, Paul Kelly, Gary Frost, Douglas J Morrison On behalf of the HUNGer Consortium

doi: 10.1136/gutjnl-2020-323609
Recent advances in clinical practice
Hepatitis D virus in 2021: virology, immunology and new treatment approaches for a difficult-to-treat disease

Stephan Urban, Christoph Neumann-Haefelin, Pietro Lampertico

doi: 10.1136/gutjnl-2020-323888

June 02, 2021

Letter
Liver injury, hypoalbuminaemia and severe SARS-CoV-2 infection
Free

Clare Elizabeth Foley, Christopher Mulvey, Maria Boylan, Niamh Reidy, Paul Reidy, David Moynan, Amy Worrall, Ger Curley, Karen Boland, Eoghan de Barra, John D Ryan

doi: 10.1136/gutjnl-2021-324570

May 31, 2021

GI cancer
Chromatin state dynamics confers specific therapeutic strategies in enhancer subtypes of colorectal cancer

Elias Orouji, Ayush T Raman, Anand K Singh, Alexey Sorokin, Emre Arslan, Archit K Ghosh, Jonathan Schulz, Christopher Terranova, Shan Jiang, Ming Tang, Mayinuer Maitituoheti, Scot C Callahan, Praveen Barrodia, Katarzyna Tomczak, Yingda Jiang, Zhiqin Jiang, Jennifer S Davis, Sukhen Ghosh, Hey Min Lee, Laura Reyes-Uribe, Kyle Chang, Yusha Liu, Huiqin Chen, Ali Azhdarinia, Jeffrey Morris, Eduardo Vilar, Kendra S Carmon, Scott E Kopetz, Kunal Rai

doi: 10.1136/gutjnl-2020-322835

May 25, 2021

Inflammatory bowel disease
Development and initial psychometric validation of a patient-reported outcome measure for Crohn’s perianal fistula: the Crohn’s Anal Fistula Quality of Life (CAF-QoL) scale

Samuel O Adegbola, Lesley Dibley, Kapil Sahnan, Tiffany Wade, Azmina Verjee, Rachel Sawyer, Sameer Mannick, Damian McCluskey, Paul Bassett, Nuha Yassin, Janindra Warusavitarne, Omar Faiz, Robin Phillips, Phil J Tozer, Christine Norton, Ailsa L Hart

doi: 10.1136/gutjnl-2019-320553
Commentary
Large-scale genetic analyses in an understudied disease: haemorrhoidal disease

Eleonora A M Festen, Rinse K Weersma

doi: 10.1136/gutjnl-2021-324817
Gut microbiota
Altered faecal microbiome and metabolome in IgG4-related sclerosing cholangitis and primary sclerosing cholangitis

Qiaoyan Liu, Bo Li, Yikang Li, Yiran Wei, Bingyuan Huang, Jubo Liang, Zhengrui You, You Li, Qiwei Qian, Rui Wang, Jun Zhang, Ruiling Chen, Zhuwan Lyu, Yong Chen, Mingxia Shi, Xiao Xiao, Qixia Wang, Qi Miao, Jing-Yuan Fang, Merrill Eric Gershwin, Min Lian, Xiong Ma, Ruqi Tang

doi: 10.1136/gutjnl-2020-323565
Letter
Radiology-guided percutaneous approach is superior to EUS for performing liver biopsies

Kaveh Hajifathalian, Kenneth J Chang, Reem Z Sharaiha

doi: 10.1136/gutjnl-2021-324867

May 24, 2021

Editor’s quiz: GI snapshot
Dysphagia: revisiting investigations

Yong Sul Kim, Ross Hansen, May YW Wong

doi: 10.1136/gutjnl-2021-324844

May 21, 2021

Hepatology
RNA helicase DDX5 enables STAT1 mRNA translation and interferon signalling in hepatitis B virus replicating hepatocytes

Jiazeng Sun, Guanhui Wu, Florentin Pastor, Naimur Rahman, Wen-Hung Wang, Zhengtao Zhang, Philippe MERLE, Lijian Hui, Anna Salvetti, David Durantel, Danzhou Yang, Ourania Andrisani

doi: 10.1136/gutjnl-2020-323126

May 20, 2021

GI cancer
Machine-learning model derived gene signature predictive of paclitaxel survival benefit in gastric cancer: results from the randomised phase III SAMIT trial

Raghav Sundar, Nesaretnam Barr Kumarakulasinghe, Yiong Huak Chan, Kazuhiro Yoshida, Takaki Yoshikawa, Yohei Miyagi, Yasushi Rino, Munetaka Masuda, Jia Guan, Junichi Sakamoto, Shiro Tanaka, Angie Lay-Keng Tan, Michal Marek Hoppe, Anand D. Jeyasekharan, Cedric Chuan Young Ng, Mark De Simone, Heike I. Grabsch, Jeeyun Lee, Takashi Oshima, Akira Tsuburaya, Patrick Tan

doi: 10.1136/gutjnl-2021-324060
Commentary
Are sugar-sweetened beverages contributing to the rising occurrence of colorectal cancer in young adults?

Neil Murphy, Peter T Campbell, Marc J Gunter

doi: 10.1136/gutjnl-2021-324614

May 18, 2021

Gut microbiota
Ginseng polysaccharides alter the gut microbiota and kynurenine/tryptophan ratio, potentiating the antitumour effect of antiprogrammed cell death 1/programmed cell death ligand 1 (anti-PD-1/PD-L1) immunotherapy

Jumin Huang, Di Liu, Yuwei Wang, Liang Liu, Jian Li, Jing Yuan, Zhihong Jiang, Zebo Jiang, WL Wendy Hsiao, Haizhou Liu, Imran Khan, Ying Xie, Jianlin Wu, Yajia Xie, Yizhong Zhang, Yu Fu, Junyi Liao, Wenjun Wang, Huanling Lai, Axi Shi, Jun Cai, Lianxiang Luo, Runze Li, Xiaojun Yao, Xingxing Fan, Qibiao Wu, Zhongqiu Liu, Peiyu Yan, Jingguang Lu, Mingrong Yang, Lin Wang, Yabing Cao, Hong Wei, Elaine Lai-Han Leung

doi: 10.1136/gutjnl-2020-321031

May 17, 2021

Stomach
Severity of gastric intestinal metaplasia predicts the risk of gastric cancer: a prospective multicentre cohort study (GCEP)

Jonathan W J Lee, Feng Zhu, Supriya Srivastava, Stephen KK Tsao, Christopher Khor, Khek Yu Ho, Kwong Ming Fock, Wee Chian Lim, Tiing Leong Ang, Wan Cheng Chow, Jimmy Bok Yan So, Calvin J Koh, Shijia Joy Chua, Andrew S Y Wong, Jaideepraj Rao, Lee Guan Lim, Khoon Lin Ling, Chung-King Chia, Choon Jin Ooi, Andrea Rajnakova, Wai Ming Yap, Manuel Salto-Tellez, Bow Ho, Richie Soong, Kee Seng Chia, Yik Ying Teo, Ming Teh, Khay-Guan Yeoh

doi: 10.1136/gutjnl-2021-324057

May 14, 2021

GI cancer
Multicentre derivation and validation of a colitis-associated colorectal cancer risk prediction web tool

Kit Curtius, Misha Kabir, Ibrahim Al Bakir, Chang Ho Ryan Choi, Juanda L Hartono, Michael Johnson, James E East, Oxford IBD Cohort Study Investigators, James O Lindsay, Roser Vega, Siwan Thomas-Gibson, Janindra Warusavitarne, Ana Wilson, Trevor A Graham, Ailsa Hart

doi: 10.1136/gutjnl-2020-323546

May 13, 2021

Letter
Intestinal microbiota defines the GUT-TESTIS axis

Emmanuelle Martinot, Laura Thirouard, Hélène Holota, Mélusine Monrose, Manon Garcia, Claude Beaudoin, David H Volle

doi: 10.1136/gutjnl-2021-324690

May 12, 2021

Letter
Reply to: “Acute-on-chronic liver failure in East-Asia: an underestimated issue with limited data”

Adrià Juanola, Gabriel Mezzano, James P Hamilton, Pere Ginès, Elsa Solà, Ruben Hernaez

doi: 10.1136/gutjnl-2021-324926

May 11, 2021

Upper GI cancer
Association between proton pump inhibitor use and gastric cancer: a population-based cohort study using two different types of nationwide databases in Korea

Seung In Seo, Chan Hyuk Park, Seng Chan You, Jae Young Kim, Kyung Joo Lee, Jinseob Kim, Yerim Kim, Jong Jin Yoo, Won-Woo Seo, Hyung Seok Lee, Woon Geon Shin

doi: 10.1136/gutjnl-2020-323845
Commentary
Prognostic value of DAXX/ATRX loss of expression and ALT activation in PanNETs: is it time for clinical implementation?

Ilaria Marinoni

doi: 10.1136/gutjnl-2021-324664
Gut microbiota
Human and preclinical studies of the host–gut microbiome co-metabolite hippurate as a marker and mediator of metabolic health

François Brial, Julien Chilloux, Trine Nielsen, Sara Vieira-Silva, Gwen Falony, Petros Andrikopoulos, Michael Olanipekun, Lesley Hoyles, Fatima Djouadi, Ana L Neves, Andrea Rodriguez-Martinez, Ghiwa Ishac Mouawad, Nicolas Pons, Sofia Forslund, Emmanuelle Le-chatelier, Aurélie Le Lay, Jeremy Nicholson, Torben Hansen, Tuulia Hyötyläinen, Karine Clément, Matej Oresic, Peer Bork, Stanislav Dusko Ehrlich, Jeroen Raes, Oluf Borbye Pedersen, Dominique Gauguier, Marc-Emmanuel Dumas

doi: 10.1136/gutjnl-2020-323314

May 10, 2021

Letter
Clomethiazole inhibits cytochrome P450 2E1 and improves alcoholic liver disease

Nicolas Hohmann, Fabian Schröder, Bernardo Moreira, Haidong Teng, Jürgen Burhenne, Thomas Bruckner, Sebastian Mueller, Walter E Haefeli, Helmut K Seitz

doi: 10.1136/gutjnl-2021-324727
Helicobacter pylori
Helicobacter pylori resistance to antibiotics in Europe in 2018 and its relationship to antibiotic consumption in the community

Francis Megraud, Robin Bruyndonckx, Samuel Coenen, Linda Wittkop, Te-Din Huang, Martin Hoebeke, Lucie Bénéjat, Philippe Lehours, Herman Goossens, Youri Glupczynski The European Helicobacter pylori Antimicrobial Susceptibility Testing Working Group

doi: 10.1136/gutjnl-2021-324032
Colon
Sugar-sweetened beverage intake in adulthood and adolescence and risk of early-onset colorectal cancer among women

Jinhee Hur, Ebunoluwa Otegbeye, Hee-Kyung Joh, Katharina Nimptsch, Kimmie Ng, Shuji Ogino, Jeffrey A Meyerhardt, Andrew T Chan, Walter C Willett, Kana Wu, Edward Giovannucci, Yin Cao

doi: 10.1136/gutjnl-2020-323450
Hepatology
Hepatobiliary phenotypes of adults with alpha-1 antitrypsin deficiency

Malin Fromme, Carolin V Schneider, Vitor Pereira, Karim Hamesch, Monica Pons, Matthias C Reichert, Federica Benini, Paul Ellis, Katrine H Thorhauge, Mattias Mandorfer, Barbara Burbaum, Vivien Woditsch, Joanna Chorostowska-Wynimko, Jef Verbeek, Frederik Nevens, Joan Genesca, Marc Miravitlles, Alexa Nuñez, Benedikt Schaefer, Heinz Zoller, Sabina Janciauskiene, Nélia Abreu, Luís Jasmins, Rui Gaspar, Rodrigo Liberal, Guilherme Macedo, Ravi Mahadeva, Catarina Gomes, Kai Markus Schneider, Michael Trauner, Aleksander Krag, Bibek Gooptu, Douglas Thorburn, Aileen Marshall, John R Hurst, David A Lomas, Frank Lammert, Nadine T Gaisa, Virginia Clark, William Griffiths, Christian Trautwein, Alice M Turner, Noel G McElvaney, Pavel Strnad

doi: 10.1136/gutjnl-2020-323729
Letter
Reducing low risk of transmissible infection in duodenoscopes: at what cost to the planet?

Anjan Dhar, Bu'Hussain Hayee, Emma Wesley, William Stableforth, Shaji Sebastian

doi: 10.1136/gutjnl-2021-324821

May 07, 2021

Intestinal inflammation
Immunoglobulin A–specific deficiency induces spontaneous inflammation specifically in the ileum

Takashi Nagaishi, Taro Watabe, Kunihiko Kotake, Toshihiko Kumazawa, Tomomi Aida, Kohichi Tanaka, Ryuichi Ono, Fumitoshi Ishino, Takako Usami, Takamasa Miura, Satomi Hirakata, Hiroko Kawasaki, Naoya Tsugawa, Daiki Yamada, Kazuhiro Hirayama, Soichiro Yoshikawa, Hajime Karasuyama, Ryuichi Okamoto, Mamoru Watanabe, Richard S Blumberg, Takahiro Adachi

doi: 10.1136/gutjnl-2020-322873
Inflammatory bowel disease
Predicting endoscopic remission in Crohn’s disease by the modified multiplier SES-CD (MM-SES-CD)

Neeraj Narula, Emily C L Wong, Jean-Frederic Colombel, William J Sandborn, John Kenneth Marshall, Marco Daperno, Walter Reinisch, Parambir S Dulai

doi: 10.1136/gutjnl-2020-323799
Letter
Response to the letter to the editor

Ji Young Bang, Robert Hawes, Shyam Varadarajulu

doi: 10.1136/gutjnl-2021-324887
Letter
NGS mismapping confounds the clinical interpretation of the PRSS1 p.Ala16Val (c.47C>T) variant in chronic pancreatitis

Emmanuelle Génin, David N Cooper, Emmanuelle Masson, Claude Férec, Jian-Min Chen

doi: 10.1136/gutjnl-2021-324943
Editor’s quiz: GI snapshot
Enormously dilated pancreatic duct

Ronald Koschny, Matthias Lang, Thilo Hackert

doi: 10.1136/gutjnl-2021-324335

May 06, 2021

Letter
Methods for handling missing segments in Crohn’s disease clinical trials: analysis from the EXTEND trial

Christopher Ma, Reena Khanna, Leonardo Guizzetti, Guangyong Zou, Brian G Feagan, Vipul Jairath

doi: 10.1136/gutjnl-2021-324658

May 05, 2021

Inflammatory bowel disease
International consensus to standardise histopathological scoring for small bowel strictures in Crohn’s disease

Ilyssa O Gordon, Dominik Bettenworth, Arne Bokemeyer, Amitabh Srivastava, Christophe Rosty, Gert de Hertogh, Marie E Robert, Mark A Valasek, Ren Mao, Jiannan Li, Noam Harpaz, Paula Borralho, Reetesh K Pai, Robert Odze, Roger Feakins, Claire E Parker, Leonardo Guizzetti, Tran Nguyen, Lisa M Shackelton, William J Sandborn, Vipul Jairath, Mark Baker, David Bruining, Joel G Fletcher, Brian G Feagan, Rish K Pai, Florian Rieder On behalf of the Stenosis Therapy and Anti-Fibrotic Research (STAR) Consortium

doi: 10.1136/gutjnl-2021-324374
Letter
SARS-CoV-2 in endoscopy: a potential way of microorganisms’ air transmission
Free

Stanislas Chaussade, Rachel Hallit, Einas Abou Ali, Arthur Belle, Maximilien Barret, Romain Coriat

doi: 10.1136/gutjnl-2021-324934
Letter
Ponder of concern and long-term safety of infants from mothers with chronic hepatitis B treated with tenofovir disoproxil

Ankur Jindal, Ashish Vyas, Garima Dubey

doi: 10.1136/gutjnl-2021-324967

April 29, 2021

Gut microbiota
Interplay between diet and gut microbiome, and circulating concentrations of trimethylamine N-oxide: findings from a longitudinal cohort of US men

Jun Li, Yanping Li, Kerry L Ivey, Dong D Wang, Jeremy E Wilkinson, Adrian Franke, Kyu Ha Lee, Andrew Chan, Curtis Huttenhower, Frank B Hu, Eric B Rimm, Qi Sun

doi: 10.1136/gutjnl-2020-322473

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