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Online First

November 29, 2022

Endoscopy
EUS-guided drainage of large walled-off pancreatic necroses using plastic versus lumen-apposing metal stents: a single-centre randomised controlled trial

John Gásdal Karstensen, Srdan Novovic, Erik Feldager Hansen, Annette Bojer Jensen, Henrik Lovendahl Joergensen, Morten Laksafoss Lauritsen, Mikkel Parsberg Werge, Palle Nordblad Schmidt

doi: 10.1136/gutjnl-2022-328225

November 28, 2022

Colon
Transcriptomic and immunophenotypic profiling reveals molecular and immunological hallmarks of colorectal cancer tumourigenesis

Jessica Roelands, Manon van der Ploeg, Marieke E Ijsselsteijn, Hao Dang, Jurjen J Boonstra, James C H Hardwick, Lukas J A C Hawinkels, Hans Morreau, Noel F C C de Miranda

doi: 10.1136/gutjnl-2022-327608

November 25, 2022

Letter
Crohn’s-associated invariant T cells (CAITs) recognise small sulfonate molecules on CD1d

Anastasia A Minervina, Mikhail V Pogorelyy, Steffen Paysen, Ulrich Luening, Frauke Degenhardt, Andre Franke, Paul G Thomas, Elisa Rosati

doi: 10.1136/gutjnl-2022-328684

November 21, 2022

Letter
Response to: Correspondence on ‘On the ethics of digestive health research in historically marginalised communities’ by Velez and Targownick

Emad Mansoor, Scott A Martin, Abe Perez, Vu Quang Nguyen, Jeffry Katz, Shubham Gupta, Fabio Cominelli

doi: 10.1136/gutjnl-2022-329038
Endoscopy news
Measuring size of smaller colorectal polyps using a virtual scale function during endoscopies

Daniel von Renteln, Roupen Djinbachian, Melissa Zarandi-Nowroozi, Mahsa Taghiakbari

doi: 10.1136/gutjnl-2022-328654

November 15, 2022

Letter
Letter to the editor: Helicobacter pylori eradication – the proof is not in the symptoms

Jan Bornschein, D Mark Pritchard, Peter Malfertheiner

doi: 10.1136/gutjnl-2022-329057

November 10, 2022

Letter
Not all that is corpus restricted is necessarily autoimmune

Edith Lahner, Emanuele Dilaghi, Ludovica Dottori, Bruno Annibale

doi: 10.1136/gutjnl-2022-328959

November 09, 2022

Endoscopy news
Health-code-based triage versus universal COVID-19 PCR testing before endoscopy in a low incidence area: a real-world experience

Zhihui Duan, Dengxiang Liu, Shengyun Zhou, Hui Li, Xiaofang Sun, Chunqian Zhao, Qiong Duan, Liwei Li, Xiaochong Zhang, Lingxuan Jin

doi: 10.1136/gutjnl-2022-328551

November 08, 2022

Letter
Gut microbiota as non-invasive diagnostic and prognostic biomarkers for natural killer/T-cell lymphoma

Zhuangzhuang Shi, Guoru Hu, Min W Li, Lei Zhang, Xin Li, Ling Li, Xinhua Wang, Xiaorui Fu, Zhenchang Sun, Xudong Zhang, Li Tian, Zhaoming Li, Wei-Hua Chen, Mingzhi Zhang

doi: 10.1136/gutjnl-2022-328256
Letter
Non-alcoholic fatty liver disease (NAFLD) is associated with an increased incidence of extrahepatic cancer

Christoph Roderburg, Karel Kostev, Alexander Mertens, Tom Luedde, Sven H Loosen

doi: 10.1136/gutjnl-2022-328887

November 07, 2022

Hepatology
Longitudinal transkingdom gut microbial approach towards decompensation in outpatients with cirrhosis

Jasmohan S Bajaj, Marcela Peña-Rodriguez, Alex La Reau, Wendy Phillips, Michael Fuchs, Brian C Davis, Richard K Sterling, Masoumeh Sikaroodi, Andrew Fagan, Amirhossein Shamsaddini, Zachariah Henseler, Tonya Ward, Puneet Puri, Hannah Lee, Patrick M Gillevet

doi: 10.1136/gutjnl-2022-328403
Inflammatory bowel disease
Hypophosphataemia following ferric derisomaltose and ferric carboxymaltose in patients with iron deficiency anaemia due to inflammatory bowel disease (PHOSPHARE-IBD): a randomised clinical trial

Heinz Zoller, Myles Wolf, Irina Blumenstein, Christian Primas, Stefan Lindgren, Lars L Thomsen, Walter Reinisch, Tariq Iqbal

doi: 10.1136/gutjnl-2022-327897
Pancreas
Molecular heterogeneity and commonalities in pancreatic cancer precursors with gastric and intestinal phenotype

Sven-Thorsten Liffers, Laura Godfrey, Lisa Frohn, Lena Haeberle, Aslihan Yavas, Rita Vesce, Wolfgang Goering, Friederike V Opitz, Nickolas Stoecklein, Wolfram Trudo Knoefel, Anna Melissa Schlitter, Guenter Klöppel, Elisa Espinet, Andreas Trumpp, Jens T Siveke, Irene Esposito

doi: 10.1136/gutjnl-2021-326550
Endoscopy
Use of over-the-scope clip (OTSC) versus standard therapy for the prevention of rebleeding in large peptic ulcers (size ≥1.5 cm): an open-labelled, multicentre international randomised controlled trial

Shannon Chan, Rapat Pittayanon, Hsiu-Po Wang, Jiann-Hwa Chen, Anthony YB Teoh, Yu Ting Kuo, Raymond SY Tang, Hon Chi Yip, Stephen Ka Kei Ng, Sunny Wong, Joyce Wing Yan Mak, Heyson Chan, Louis Lau, Rashid N Lui, Marc Wong, Rungsun Rerknimitr, Enders K Ng, Philip Wai Yan Chiu

doi: 10.1136/gutjnl-2022-327007

November 04, 2022

Commentary
Gnotobiotic mice housing conditions makes the difference in the context of obesity!

Patrice D Cani, Claude Knauf

doi: 10.1136/gutjnl-2022-328532
Letter
Reply: Immortal time bias in a retrospective study examining colorectal cancer mortality according to adherence to colonoscopy

Manuel Zorzi, Jessica Battagello, Claudio Barbiellini Amidei

doi: 10.1136/gutjnl-2022-328905

November 03, 2022

Letter
Diameter of the shunt: the missing link in the appraisal of pTIPS in patients with cirrhosis with previous hepatic encephalopathy

Thierry Thevenot, Maxime Desmarets, Delphine Weil, Vincent Di Martino

doi: 10.1136/gutjnl-2022-328761

November 02, 2022

Letter
On the ethics of digestive health research in historically marginalised communities

Christopher Vélez, Laura E Targownik

doi: 10.1136/gutjnl-2022-328829
Letter
Reply to Newman et al ‘Response to epidemiology of inflammatory bowel disease in men with high-risk homosexual activity’

Emad Mansoor, Scott A Martin, Abe Perez, Vu Quang Nguyen, Jeffry A Katz, Shubham Gupta, Fabio Cominelli

doi: 10.1136/gutjnl-2022-328883
Commentary
Picking up microbial clues in early-onset colorectal cancer

Neelendu Dey

doi: 10.1136/gutjnl-2022-328427

October 31, 2022

Hepatology
Engineered anti-PDL1 with IFNα targets both immunoinhibitory and activating signals in the liver to break HBV immune tolerance

Chao-Yang Meng, Shiyu Sun, Yong Liang, Hairong Xu, Chao Zhang, Min Zhang, Fu-Sheng Wang, Yang-Xin Fu, Hua Peng

doi: 10.1136/gutjnl-2022-327059

October 28, 2022

Upper GI cancer
Epithelial SOX9 drives progression and metastases of gastric adenocarcinoma by promoting immunosuppressive tumour microenvironment

Yibo Fan, Yuan Li, Xiaodan Yao, Jiangkang Jin, Ailing Scott, Bovey Liu, Shan Wang, Longfei Huo, Ying Wang, Ruiping Wang, Melissa Pool Pizzi, Lang Ma, Shan Shao, Matheus Sewastjanow-Silva, Rebecca Waters, Deyali Chatterjee, Bin Liu, Namita Shanbhag, Guang Peng, George Adrian Calin, Pawel Karol Mazur, Samir M Hanash, Jo Ishizawa, Yuki Hirata, Osamu Nagano, Zhenning Wang, Linghua Wang, Wa Xian, Frank McKeon, Jaffer A Ajani, Shumei Song

doi: 10.1136/gutjnl-2021-326581
Endoscopy
Rates of repeated colonoscopies to clean the colon from low-risk and high-risk adenomas: results from the EPoS trials

Frederik Emil Juul, Kjetil Garborg, Eugen Nesbakken, Magnus Løberg, Paulina Wieszczy, Joaquín Cubiella, Mette Kalager, Michael F Kaminski, Rune Erichsen, Hans-Olov Adami, Monika Ferlitsch, Siv K B Furholm, Ann G Zauber, Enrique Quintero, Marek Bugajski, Øyvind Holme, Evelien Dekker, Rodrigo Jover, Michael Bretthauer

doi: 10.1136/gutjnl-2022-327696
Letter
Overcoming regional limitations: transfer learning for cross-regional microbial-based diagnosis of diseases

Nan Wang, Mingyue Cheng, Kang Ning

doi: 10.1136/gutjnl-2022-328216
Colon
Irritable bowel syndrome: treatment based on pathophysiology and biomarkers

Michael Camilleri, Guy Boeckxstaens

doi: 10.1136/gutjnl-2022-328515
Letter
APC mosaicism, not always isolated: two first-degree relatives with apparently distinct APC mosaicism

Diantha Terlouw, Frederik J Hes, Manon Suerink, Arnoud Boot, Alexandra M J Langers, Carli M Tops, Monique E van Leerdam, Christi J van Asperen, Steve G Rozen, Emilia K Bijlsma, Tom van Wezel, Hans Morreau, Maartje Nielsen

doi: 10.1136/gutjnl-2022-328540
Commentary
Going deeper: molecular inflammatory scores in IBD

James C Lee

doi: 10.1136/gutjnl-2022-328539
Oesophagus
Vitamin D receptor and STAT6 interactome governs oesophageal epithelial barrier responses to IL-13 signalling

Michael Brusilovsky, Mark Rochman, Tetsuo Shoda, Michael Kotliar, Julie M Caldwell, Lydia E Mack, John A Besse, Xiaoting Chen, Matthew T Weirauch, Artem Barski, Marc E Rothenberg

doi: 10.1136/gutjnl-2022-327276

October 25, 2022

Hepatology
Targeting tumour-intrinsic N⁷-methylguanosine tRNA modification inhibits MDSC recruitment and improves anti-PD-1 efficacy

Haining Liu, Xuezhen Zeng, Xuxin Ren, Yifan Zhang, Manling Huang, Li Tan, Zihao Dai, Jiaming Lai, Wenxuan Xie, Zebin Chen, Sui Peng, Lixia Xu, Shuling Chen, Shunli Shen, Ming Kuang, Shuibin Lin

doi: 10.1136/gutjnl-2022-327230

October 21, 2022

Inflammatory bowel disease
Rewiring the altered tryptophan metabolism as a novel therapeutic strategy in inflammatory bowel diseases

Chloé Michaudel, Camille Danne, Allison Agus, Aurélie Magniez, Anne Aucouturier, Madeleine Spatz, Antoine Lefevre, Julien Kirchgesner, Nathalie Rolhion, Yazhou Wang, Aonghus Lavelle, Chloé Galbert, Gregory Da Costa, Maxime Poirier, Alexia Lapière, Julien Planchais, Petr Nádvorník, Peter Illes, Cyriane Oeuvray, Laura Creusot, Marie-Laure Michel, Nicolas Benech, Anne Bourrier, Isabelle Nion-Larmurier, Cecilia Landman, Mathias L Richard, Patrick Emond, Philippe Seksik, Laurent Beaugerie, Rafael Rose Arguello, David Moulin, Sridhar Mani, Zdenek Dvorák, Luis G Bermúdez-Humarán, Philippe Langella, Harry Sokol

doi: 10.1136/gutjnl-2022-327337

October 19, 2022

Commentary
Prophylactic vaccination against hepatitis D virus superinfection: from fiction to reality?

Julia Lang-Meli, Christoph Neumann-Haefelin

doi: 10.1136/gutjnl-2022-328381
GI cancer
Epithelial presenilin-1 drives colorectal tumour growth by controlling EGFR-COX2 signalling

Reyes Gamez-Belmonte, Mousumi Mahapatro, Lena Erkert, Miguel Gonzalez-Acera, Elisabeth Naschberger, Yuqiang Yu, Mireia Tena-Garitaonaindia, Jay V Patankar, Yara Wagner, Eva Podstawa, Lena Schödel, Marvin Bubeck, Markus F Neurath, Michael Stürzl, Christoph Becker

doi: 10.1136/gutjnl-2022-327323

October 14, 2022

Gut microbiota
Postinfective bowel dysfunction following Campylobacter enteritis is characterised by reduced microbiota diversity and impaired microbiota recovery

Jonna Jalanka, David Gunn, Gulzar Singh, Shanthi Krishnasamy, Melanie Lingaya, Fiona Crispie, Laura Finnegan, Paul Cotter, Louise James, Adam Nowak, Giles Major, Robin C Spiller

doi: 10.1136/gutjnl-2021-326828
Neurogastroenterology
Identification of bacterial lipopeptides as key players in IBS

Camille Petitfils, Sarah Maurel, Gaelle Payros, Amandine Hueber, Bahija Agaiz, Géraldine Gazzo, Rémi Marrocco, Frédéric Auvray, Geoffrey Langevin, Jean-Paul Motta, Pauline Floch, Marie Tremblay-Franco, Jean-Marie Galano, Alexandre Guy, Thierry Durand, Simon Lachambre, Anaëlle Durbec, Hind Hussein, Lisse Decraecker, Justine Bertrand-Michel, Abdelhadi Saoudi, Eric Oswald, Pierrick Poisbeau, Gilles Dietrich, Chloe Melchior, Guy Boeckxstaens, Matteo Serino, Pauline Le Faouder, Nicolas Cenac

doi: 10.1136/gutjnl-2022-328084
Upper GI cancer
Population-based investigation of common and deviating patterns of gastric cancer and oesophageal cancer incidence across populations and time

Mengmeng Li, Jin Young Park, Mahdi Sheikh, Violet Kayamba, Harriet Rumgay, Mazda Jenab, Clement Tetteh Narh, Behnoush Abedi-Ardekani, Eileen Morgan, Catherine de Martel, Valerie McCormack, Melina Arnold

doi: 10.1136/gutjnl-2022-328233
Nutrition
Effect of endoscopic sleeve gastroplasty on gastric emptying, motility and hormones: a comparative prospective study

Eric J Vargas, Monika Rizk, Jacky Gomez-Villa, Phillip K Edwards, Veeravich Jaruvongvanich, Andrew C Storm, Andres Acosta, David Lake, Jeff Fidler, Adil E Bharucha, Michael Camilleri, Barham K Abu Dayyeh

doi: 10.1136/gutjnl-2022-327816

October 13, 2022

Letter
Role of the DOMINO diet application for managing IBS in primary care and beyond

Jan Tack, Karen Van den Houte, Florencia Carbone

doi: 10.1136/gutjnl-2022-328315
Letter
Response to letter to the editor: lumen-apposing metal stents versus double-pigtail plastic stents for infected necrotising pancreatitis

Lotte Boxhoorn, Robert C Verdonk, Rogier P Voermans On behalf of the Dutch Pancreatitis Study Group

doi: 10.1136/gutjnl-2022-328686
Guidelines
Green endoscopy: British Society of Gastroenterology (BSG), Joint Accreditation Group (JAG) and Centre for Sustainable Health (CSH) joint consensus on practical measures for environmental sustainability in endoscopy

Shaji Sebastian, Anjan Dhar, Robin Baddeley, Leigh Donnelly, Rosemary Haddock, Ramesh Arasaradnam, Archibald Coulter, Benjamin Robert Disney, Helen Griffiths, Christopher Healey, Rosie Hillson, Ingeborg Steinbach, Sarah Marshall, Arun Rajendran, Andrew Rochford, Siwan Thomas-Gibson, Sandeep Siddhi, William Stableforth, Emma Wesley, Bernard Brett, Allan John Morris, Andrew Douds, Mark Giles Coleman, Andrew M Veitch, Bu'Hussain Hayee

doi: 10.1136/gutjnl-2022-328460
Letter
Response to Mansoor et al: ‘epidemiology of inflammatory bowel disease in men with high-risk homosexual activity’

Kira L Newman, Kara Jencks, Victor Chedid, Sonali Paul, Peter D R Higgins, Sunanda V Kane, Millie Long

doi: 10.1136/gutjnl-2022-328802

October 07, 2022

Letter
Dynamic changes in host immune system and gut microbiota are associated with the production of SARS-CoV-2 antibodies

Maozhen Han, Yixuan Huang, Hongya Gui, Yixuan Xiao, Maozhang He, Jiling Liu, Xiujing Cao, Meijuan Zheng, Min Lu, Weihua Jia, Hui Li, Xiaoyan Wang, Na Zhang, Shu-an Kong, Xiaohui Liu, Yonggui Wu, Fengchang Wu, Shenghai Huang

doi: 10.1136/gutjnl-2022-327561

October 04, 2022

Letter
Most excess years of potential life loss among individuals with cirrhosis during the pandemic were not related to COVID-19

Yunyu Zhao, Yee Hui Yeo, Jamil Samaan, Fan Lv, Xinyuan He, Ning Gao, Justin Park, Ju Dong Yang, Walid Ayoub, Michelle C Odden, Fanpu Ji, Mindie H Nguyen

doi: 10.1136/gutjnl-2022-328188
Letter
SARS-CoV-2 vaccination in patients with GI and hepatobiliary carcinoma: a call for booster vaccination

Malte Benedikt Monin, Leona Baier, Moritz Berger, Jens Gabriel Gorny, Taotao Zhou, Robert Mahn, Farsaneh Sadeghlar, Christian Möhring, Kathrin van Bremen, Christoph Boesecke, Jürgen Rockstroh, Christian Strassburg, Anna-Maria Eis-Hübinger, Maria Agnes Gonzalez-Carmona

doi: 10.1136/gutjnl-2022-328169
Letter
COVID-19 and liver injury: hypoalbuminaemia and γGT should be observed at hospital admission

Sabine Weber, Alexander L Gerbes

doi: 10.1136/gutjnl-2022-328214
Letter
Withdrawal of the British Society of Gastroenterology IBD risk grid for COVID-19 severity

Charlie W Lees, Tariq Ahmad, Christopher Andrew Lamb, Nick Powell, Shahida Din, Rachel Cooney, Nicholas A Kennedy, Rachel Ainley, Ruth Wakeman, Christian Philipp Selinger

doi: 10.1136/gutjnl-2022-327409
Letter
COVID-19 vaccine effectiveness and community prevalence of Alpha, Delta and Omicron variants in patients with cirrhosis

Binu V John, Dustin R Bastaich, Raphaella D Ferreira, Akash Doshi, Tamar H Taddei, David E Kaplan, Seth Spector, Yangyang Deng, Bassam Dahman

doi: 10.1136/gutjnl-2022-327799
Letter
Post-acute COVID-19 syndrome and gut dysbiosis linger beyond 1 year after SARS-CoV-2 clearance

Qi Su, Raphaela Iris Lau, Qin Liu, Francis Ka Leung Chan, Siew Chien Ng

doi: 10.1136/gutjnl-2022-328319
Letter
Great escape: how infectious SARS-CoV-2 avoids inactivation by gastric acidity and intestinal bile

Malak A Esseili

doi: 10.1136/gutjnl-2021-326624

October 03, 2022

Gut immunity
TiO₂ nanoparticles abrogate the protective effect of the Crohn’s disease-associated variation within the PTPN22 gene locus

Marlene Schwarzfischer, Anna Niechcial, Kristina Handler, Yasser Morsy, Marcin Wawrzyniak, Andrea S Laimbacher, Kirstin Atrott, Roberto Manzini, Katharina Baebler, Larissa Hering, Egle Katkeviciutė, Janine Häfliger, Silvia Lang, Maja E Keller, Jérôme Woodtli, Lisa Eisenbeiss, Thomas Kraemer, Elisabeth M Schraner, Mahesa Wiesendanger, Sebastian Zeissig, Gerhard Rogler, Andreas E Moor, Michael Scharl, Marianne R Spalinger

doi: 10.1136/gutjnl-2021-325911
Inflammatory bowel disease
NOX1 is essential for TNFα-induced intestinal epithelial ROS secretion and inhibits M cell signatures

Nai-Yun Hsu, Shikha Nayar, Kyle Gettler, Sayali Talware, Mamta Giri, Isaac Alter, Carmen Argmann, Ksenija Sabic, Tin Htwe Thin, Huai-Bin Mabel Ko, Robert Werner, Christopher Tastad, Thaddeus Stappenbeck, Aline Azabdaftari, Holm H Uhlig, Ling-Shiang Chuang, Judy H Cho

doi: 10.1136/gutjnl-2021-326305

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