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BMJ Journals More

Online First

January 13, 2018

PostScript
Risk factors for gastric cancer: is it time to discard PPIs?

Lucrezia Laterza, Franco Scaldaferri, Antonio Gasbarrini

doi: 10.1136/gutjnl-2017-315621

January 12, 2018

Post script
Several aspects in study design need further consideration

Cheng-Bei Zhou, Jing-Yuan Fang

doi: 10.1136/gutjnl-2017-315692
PostScript
Evidence suggests that germline RNF43 mutations are a rare cause of serrated polyposis

Isabel Quintana, Raquel Mejías-Luque, Mariona Terradas, Matilde Navarro, Virginia Piñol, Pilar Mur, Sami Belhadj, Elia Grau, Esther Darder, Ares Solanes, Joan Brunet, Gabriel Capellá, Markus Gerhard, Laura Valle

doi: 10.1136/gutjnl-2017-315733

January 11, 2018

PostScript
Exosomal adrenomedullin derived from cancer-associated fibroblasts promotes lipolysis in adipose tissue

Fanyang Kong, Lei Li, Yiqi Du, Huiyun Zhu, Zhaoshen Li, Xiangyu Kong

doi: 10.1136/gutjnl-2017-315778

January 10, 2018

Inflammatory bowel disease
Fetal and early life antibiotics exposure and very early onset inflammatory bowel disease: a population-based study

Anne K Örtqvist, Cecilia Lundholm, Jonas Halfvarson, Jonas F Ludvigsson, Catarina Almqvist

doi: 10.1136/gutjnl-2017-314352

January 06, 2018

Oesophagus
Efficacy of endoscopic screening for esophageal cancer in China (ESECC): design and preliminary results of a population-based randomised controlled trial

Zhonghu He, Zhen Liu, Mengfei Liu, Chuanhai Guo, Ruiping Xu, Fenglei Li, Anxiang Liu, Haijun Yang, Lin Shen, Qi Wu, Liping Duan, Xiang Li, Chaoting Zhang, Yaqi Pan, Hong Cai, Yang Ke

doi: 10.1136/gutjnl-2017-315520
Gastroduodenal
Gastritis staging in the endoscopic follow-up for the secondary prevention of gastric cancer: a 5-year prospective study of 1755 patients

Massimo Rugge, Alberto Meggio, Cecilia Pravadelli, Mattia Barbareschi, Matteo Fassan, Maria Gentilini, Manuel Zorzi, Giovanni De Pretis, David Y Graham, Robert M Genta

doi: 10.1136/gutjnl-2017-314600

January 03, 2018

Endoscopy
Multicentre prospective evaluation of real-time optical diagnosis of T1 colorectal cancer in large non-pedunculated colorectal polyps using narrow band imaging (the OPTICAL study)

Yara Backes, Matthijs P Schwartz, Frank ter Borg, Frank H J Wolfhagen, John N Groen, Wouter H de Vos tot Nederveen Cappel, Jeroen van Bergeijk, Joost M J Geesing, Bernhard W M Spanier, Paul Didden, Frank P Vleggaar, Miangela M Lacle, Sjoerd G Elias, Leon M G Moons on behalf of the Dutch T1 CRC Working Group

doi: 10.1136/gutjnl-2017-314723
Endoscopy
Acute sedation-associated complications in GI endoscopy (ProSed 2 Study): results from the prospective multicentre electronic registry of sedation-associated complications

Angelika Behrens, Anton Kreuzmayr, Hendrik Manner, Herbert Koop, Albrecht Lorenz, Claus Schaefer, Mathais Plauth, Jens-Uwe Jetschmann, Christian von Tirpitz, Marcus Ewald, Michael Sackmann, Wanja Renner, Martin Krüger, Dieter Schwab, Werner Hoffmann, Olaf Engelke, Oliver Pech, Frank Kullmann, Sonja Pampuch, Berthold Lenfers, Uwe Weickert, Dieter Schilling, Stephan Boehm, Susanne Beckebaum, Vito Cicinnati, Joachim F Erckenbrecht, Franz Ludwig Dumoulin, Claus Benz, Thomas Rabenstein, Georg Haltern, Martin Balsliemke, Christian de Mas, Gerhard Kleber, Christian Pehl, Christoph Vogt, Ralf Kiesslich, Wolfgang Fischbach, Irmtraut Koop, Jens Kuehne, Matthias Breidert, Nils Lennart Sass, Andrea May, Christian Friedrich, Ronni Veitt, Rainer Porschen, Mark Ellrichmann, Alexander Arlt, Wolfgang Schmitt, Markus Dollhopf, Werner Schmidbaur, Axel Dignass, Volker Schmitz, J Labenz, Gernot Kaiser, Alexander Krannich, Nico Barteska, Christian Ell

doi: 10.1136/gutjnl-2015-311037
PostScript
Role of thiopurines as disease-modifying agents in Crohn’s disease

Jonathan Blackwell, Sonia Saxena, Richard C Pollok

doi: 10.1136/gutjnl-2017-315840
PostScript
Integrin a6 loss promotes colitis-associated colorectal cancer. Response to: “Integrin a6 variants and colorectal cancer” by Beaulieu JF

Adèle De Arcangelis, Mathias Chamaillard, Patricia Simon-Assmann, Michel Labouesse

doi: 10.1136/gutjnl-2017-315727
PostScript
Proton-pump inhibitors and increased gastric cancer risk: time-related biases

Samy Suissa, Alain Suissa

doi: 10.1136/gutjnl-2017-315729

December 15, 2017

Inflammatory bowel disease
Randomised trial and open-label extension study of an anti-interleukin-6 antibody in Crohn’s disease (ANDANTE I and II)

Silvio Danese, Séverine Vermeire, Paul Hellstern, Remo Panaccione, Gerhard Rogler, Gerald Fraser, Anna Kohn, Pierre Desreumaux, Rupert W Leong, Gail M Comer, Fabio Cataldi, Anindita Banerjee, Mary K Maguire, Cheryl Li, Natalie Rath, Jean Beebe, Stefan Schreiber

doi: 10.1136/gutjnl-2017-314562
PostScript
Helicobacter pylori eradication failure may have confounded the recent large-scale health database study that showed proton pump inhibitors increase gastric cancer risk

Hidekazu Suzuki, Juntaro Matsuzaki

doi: 10.1136/gutjnl-2017-315698
Endoscopy news
Near-infrared fluorescence molecular endoscopy detects dysplastic oesophageal lesions using topical and systemic tracer of vascular endothelial growth factor A

Wouter B Nagengast, Elmire Hartmans, Pilar B Garcia-Allende, Frans T M Peters, Matthijs D Linssen, Maximilian Koch, Marjory Koller, Jolien J J Tjalma, Arend Karrenbeld, Annelies Jorritsma-Smit, Jan H Kleibeuker, Gooitzen M van Dam, Vasilis Ntziachristos

doi: 10.1136/gutjnl-2017-314953

December 07, 2017

Hepatology
Hepatitis delta virus persists during liver regeneration and is amplified through cell division both in vitro and in vivo

Katja Giersch, Oliver D Bhadra, Tassilo Volz, Lena Allweiss, Kristoffer Riecken, Boris Fehse, Ansgar W Lohse, Joerg Petersen, Camille Sureau, Stephan Urban, Maura Dandri, Marc Lütgehetmann

doi: 10.1136/gutjnl-2017-314713

November 27, 2017

Hepatology
A trivalent HCV vaccine elicits broad and synergistic polyclonal antibody response in mice and rhesus monkey

Xuesong Wang, Yu Yan, Tianyu Gan, Xi Yang, Dapeng Li, Dongming Zhou, Qiang Sun, Zhong Huang, Jin Zhong

doi: 10.1136/gutjnl-2017-314870

November 20, 2017

PostScript
Coeliac biopsies: numbers are valid, alphabets not

Kamran Rostami, Arzu Ensari, Carolina Ciacci, Amitabh Srivastava, Umberto Volta, Vincenzo Villanacci, Michael N Marsh

doi: 10.1136/gutjnl-2017-315517
Pancreas
Resection of pancreatic cancer in Europe and USA: an international large-scale study highlighting large variations

Lei Huang, Lina Jansen, Yesilda Balavarca, Esther Molina-Montes, Masoud Babaei, Lydia van der Geest, Valery Lemmens, Liesbet Van Eycken, Harlinde De Schutter, Tom B Johannesen, Claus W Fristrup, Michael B Mortensen, Maja Primic-Žakelj, Vesna Zadnik, Nikolaus Becker, Thilo Hackert, Margit Mägi, Tiziana Cassetti, Romano Sassatelli, Robert Grützmann, Susanne Merkel, Ana F Gonçalves, Maria J Bento, Péter Hegyi, Gábor Lakatos, Andrea Szentesi, Michel Moreau, Tony van de Velde, Annegien Broeks, Milena Sant, Pamela Minicozzi, Vincenzo Mazzaferro, Francisco X Real, Alfredo Carrato, Xavier Molero, Marc G Besselink, Núria Malats, Markus W Büchler, Petra Schrotz-King, Hermann Brenner

doi: 10.1136/gutjnl-2017-314828

November 17, 2017

Inflammatory bowel disease
Cumulative burden of inflammation predicts colorectal neoplasia risk in ulcerative colitis: a large single-centre study

Chang-Ho Ryan Choi, Ibrahim Al Bakir, Nik-Sheng (John) Ding, Gui-Han Lee, Alan Askari, Janindra Warusavitarne, Morgan Moorghen, Adam Humphries, Ana Ignjatovic-Wilson, Siwan Thomas-Gibson, Brian P Saunders, Matthew D Rutter, Trevor A Graham, Ailsa L Hart

doi: 10.1136/gutjnl-2017-314190

November 15, 2017

Original Article
DNA methylation defines regional identity of human intestinal epithelial organoids and undergoes dynamic changes during development

Judith Kraiczy, Komal M Nayak, Kate J Howell, Alexander Ross, Jessica Forbester, Camilla Salvestrini, Roxana Mustata, Sally Perkins, Amanda Andersson-Rolf, Esther Leenen, Anke Liebert, Ludovic Vallier, Philip C Rosenstiel, Oliver Stegle, Gordon Dougan, Robert Heuschkel, Bon-Kyoung Koo, Matthias Zilbauer

doi: 10.1136/gutjnl-2017-314817

November 10, 2017

Endoscopy
Wide-field endoscopic mucosal resection versus endoscopic submucosal dissection for laterally spreading colorectal lesions: a cost-effectiveness analysis

Farzan F Bahin, Steven J Heitman, Khalid N Rasouli, Hema Mahajan, Duncan McLeod, Eric Y T Lee, Stephen J Williams, Michael J Bourke

doi: 10.1136/gutjnl-2017-313823

November 09, 2017

Colon
Real-time differentiation of adenomatous and hyperplastic diminutive colorectal polyps during analysis of unaltered videos of standard colonoscopy using a deep learning model

Michael F Byrne, Nicolas Chapados, Florian Soudan, Clemens Oertel, Milagros Linares Pérez, Raymond Kelly, Nadeem Iqbal, Florent Chandelier, Douglas K Rex

doi: 10.1136/gutjnl-2017-314547

November 07, 2017

GI cancer
SRSF6-regulated alternative splicing that promotes tumour progression offers a therapy target for colorectal cancer

Ledong Wan, Wenying Yu, Enhui Shen, Wenjie Sun, Yuan Liu, Jianlu Kong, Yihua Wu, Fengyan Han, Lei Zhang, Tianze Yu, Yuwei Zhou, Sunzhe Xie, Enping Xu, Honghe Zhang, Maode Lai

doi: 10.1136/gutjnl-2017-314983

November 03, 2017

GI cancer
Genome-wide DNA methylation analysis reveals a prognostic classifier for non-metastatic colorectal cancer (ProMCol classifier)

Melanie Gündert, Dominic Edelmann, Axel Benner, Lina Jansen, Min Jia, Viola Walter, Phillip Knebel, Esther Herpel, Jenny Chang-Claude, Michael Hoffmeister, Hermann Brenner, Barbara Burwinkel

doi: 10.1136/gutjnl-2017-314711
Colon
Long-term performance of colorectal cancer screening programmes based on the faecal immunochemical test

Manuel Zorzi, Cesare Hassan, Giulia Capodaglio, Chiara Fedato, Adriana Montaguti, Anna Turrin, Alberto Rosano, Daniele Monetti, Carmen Stocco, Susanna Baracco, Francesca Russo, Alessandro Repici, Massimo Rugge

doi: 10.1136/gutjnl-2017-314753

October 30, 2017

Oesophagus
Methylation panel is a diagnostic biomarker for Barrett’s oesophagus in endoscopic biopsies and non-endoscopic cytology specimens

Hamza Chettouh, Oliver Mowforth, Núria Galeano-Dalmau, Navya Bezawada, Caryn Ross-Innes, Shona MacRae, Irene Debiram-Beecham, Maria O’Donovan, Rebecca C Fitzgerald

doi: 10.1136/gutjnl-2017-314026

October 28, 2017

Pancreas
Tailored first-line and second-line CDK4-targeting treatment combinations in mouse models of pancreatic cancer

Angela Chou, Danielle Froio, Adnan M Nagrial, Ashleigh Parkin, Kendelle J Murphy, Venessa T Chin, Dalia Wohl, Angela Steinmann, Rhys Stark, Alison Drury, Stacey N Walters, Claire Vennin, Andrew Burgess, Mark Pinese, Lorraine A Chantrill, Mark J Cowley, Timothy J Molloy, , Nicola Waddell, Amber Johns, Sean M Grimmond, David K Chang, Andrew V Biankin, Owen J Sansom, Jennifer P Morton, Shane T Grey, Thomas R Cox, John Turchini, Jaswinder Samra, Stephen J Clarke, Paul Timpson, Anthony J Gill, Marina Pajic Australian Pancreatic Cancer Genome Initiative (APGI)

doi: 10.1136/gutjnl-2017-315144

October 26, 2017

Hepatology
Liver Reptin/RUVBL2 controls glucose and lipid metabolism with opposite actions on mTORC1 and mTORC2 signalling

Joaquim Javary, Nathalie Allain-Courtois, Nicolas Saucisse, Pierre Costet, Capucine Heraud, Fadila Benhamed, Rémi Pierre, Corinne Bure, Nestor Pallares-Lupon, Marcio Do Cruzeiro, Catherine Postic, Daniela Cota, Pierre Dubus, Jean Rosenbaum, Samira Benhamouche-Trouillet

doi: 10.1136/gutjnl-2017-314208
GI cancer
Outcomes following polypectomy for malignant colorectal polyps are similar to those following surgery in the general population

Anthony Lopez, Anne-Marie Bouvier, Valérie Jooste, Vanessa Cottet, Gaëlle Romain, Jean Faivre, Sylvain Manfredi, Come Lepage

doi: 10.1136/gutjnl-2016-312093

October 21, 2017

PostScript
ROC-king onwards: intraepithelial lymphocyte counts, distribution and role in coeliac disease mucosal interpretation

Georg Oberhuber, Alexander Moschen, Andreas Entenmann, Harald Vogelsang

doi: 10.1136/gutjnl-2017-315403

October 07, 2017

Endoscopy news
EUS-guided fine needle biopsy of pancreatic masses can yield true histology: results of a randomised trial

Ji Young Bang, Shantel Hebert-Magee, Udayakumar Navaneethan, Muhammad K Hasan, Robert Hawes, Shyam Varadarajulu

doi: 10.1136/gutjnl-2017-315154

October 05, 2017

GI cancer
Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer

Ludovic Barault, Alessio Amatu, Giulia Siravegna, Agostino Ponzetti, Sebastian Moran, Andrea Cassingena, Benedetta Mussolin, Chiara Falcomatà, Alexandra M Binder, Carmen Cristiano, Daniele Oddo, Simonetta Guarrera, Carlotta Cancelliere, Sara Bustreo, Katia Bencardino, Sean Maden, Alice Vanzati, Patrizia Zavattari, Giuseppe Matullo, Mauro Truini, William M Grady, Patrizia Racca, Karin B Michels, Salvatore Siena, Manel Esteller, Alberto Bardelli, Andrea Sartore-Bianchi, Federica Di Nicolantonio

doi: 10.1136/gutjnl-2016-313372

September 28, 2017

Pancreas
Preoperative next-generation sequencing of pancreatic cyst fluid is highly accurate in cyst classification and detection of advanced neoplasia

Aatur D Singhi, Kevin McGrath, Randall E Brand, Asif Khalid, Herbert J Zeh, Jennifer S Chennat, Kenneth E Fasanella, Georgios I Papachristou, Adam Slivka, David L Bartlett, Anil K Dasyam, Melissa Hogg, Kenneth K Lee, James Wallis Marsh, Sara E Monaco, N Paul Ohori, James F Pingpank, Allan Tsung, Amer H Zureikat, Abigail I Wald, Marina N Nikiforova

doi: 10.1136/gutjnl-2016-313586
Endoscopy
A comparison of the resection rate for cold and hot snare polypectomy for 4–9 mm colorectal polyps: a multicentre randomised controlled trial (CRESCENT study)

Takuji Kawamura, Yoji Takeuchi, Satoshi Asai, Isao Yokota, Eisuke Akamine, Minoru Kato, Takuji Akamatsu, Kazuhiro Tada, Yoriaki Komeda, Mineo Iwatate, Ken Kawakami, Michiko Nishikawa, Daisuke Watanabe, Atsushi Yamauchi, Norimasa Fukata, Masaaki Shimatani, Makoto Ooi, Koichi Fujita, Yasushi Sano, Hiroshi Kashida, Satoru Hirose, Hiroyoshi Iwagami, Noriya Uedo, Satoshi Teramukai, Kiyohito Tanaka

doi: 10.1136/gutjnl-2017-314215
Hepatology
Development of diagnostic criteria and a prognostic score for hepatitis B virus-related acute-on-chronic liver failure

Tianzhou Wu, Jiang Li, Li Shao, Jiaojiao Xin, Longyan Jiang, Qian Zhou, Dongyan Shi, Jing Jiang, Suwan Sun, Linfeng Jin, Ping Ye, Lingling Yang, Yinyun Lu, Tan Li, Jianrong Huang, Xiaowei Xu, Jiajia Chen, Shaorui Hao, Yuemei Chen, Shaojie Xin, Zhiliang Gao, Zhongping Duan, Tao Han, Yuming Wang, Jianhe Gan, Tingting Feng, Chen Pan, Yongping Chen, Hai Li, Yan Huang, Qing Xie, Shumei Lin, Lanjuan Li, Jun Li on behalf of the Chinese Group on the Study of Severe Hepatitis B (COSSH).

doi: 10.1136/gutjnl-2017-314641
Endoscopy
Modifiable factors associated with patient-reported pain during and after screening colonoscopy

Marek Bugajski, Paulina Wieszczy, Geir Hoff, Maciej Rupinski, Jaroslaw Regula, Michal Filip Kaminski

doi: 10.1136/gutjnl-2017-313905
Endoscopy
International development and validation of a classification system for the identification of Barrett’s neoplasia using acetic acid chromoendoscopy: the Portsmouth acetic acid classification (PREDICT)

Kesavan Kandiah, Fergus J Q Chedgy, Sharmila Subramaniam, Gaius Longcroft-Wheaton, Paul Bassett, Alessandro Repici, Prateek Sharma, Oliver Pech, Pradeep Bhandari

doi: 10.1136/gutjnl-2017-314512
Hepatology
Covered TIPS versus endoscopic band ligation plus propranolol for the prevention of variceal rebleeding in cirrhotic patients with portal vein thrombosis: a randomised controlled trial

Yong Lv, Xingshun Qi, Chuangye He, Zhengyu Wang, Zhanxin Yin, Jing Niu, Wengang Guo, Wei Bai, Hongbo Zhang, Huahong Xie, Liping Yao, Jianhong Wang, Tao Li, Qiuhe Wang, Hui Chen, Haibo Liu, Enxing Wang, Dongdong Xia, Bohan Luo, Xiaomei Li, Jie Yuan, Na Han, Ying Zhu, Jielai Xia, Hongwei Cai, Zhiping Yang, Kaichun Wu, Daiming Fan, Guohong Han For the PVT-TIPS Study Group.

doi: 10.1136/gutjnl-2017-314634

September 26, 2017

Gut microbiota
A randomised trial of the effect of omega-3 polyunsaturated fatty acid supplements on the human intestinal microbiota

Henry Watson, Suparna Mitra, Fiona C Croden, Morag Taylor, Henry M Wood, Sarah L Perry, Jade A Spencer, Phil Quirke, Giles J Toogood, Clare L Lawton, Louise Dye, Paul M Loadman, Mark A Hull

doi: 10.1136/gutjnl-2017-314968

September 12, 2017

Hepatology
Regulatory NK cells mediated between immunosuppressive monocytes and dysfunctional T cells in chronic HBV infection

Haijun Li, Naicui Zhai, Zhongfeng Wang, Hongxiao Song, Yang Yang, An Cui, Tianyang Li, Guangyi Wang, Junqi Niu, Ian Nicholas Crispe, Lishan Su, Zhengkun Tu

doi: 10.1136/gutjnl-2017-314098

September 06, 2017

Hepatology
Fatty acids promote fatty liver disease via the dysregulation of 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway

Meng Li, Chengfu Xu, Junping Shi, Jiexia Ding, Xingyong Wan, Dahua Chen, Jianguo Gao, Chunxiao Li, Jie Zhang, Yiming Lin, Zhenhua Tu, Xiaoni Kong, Youming Li, Chaohui Yu

doi: 10.1136/gutjnl-2017-313778

February 24, 2017

Obituary
Juan Rodés. A successful and extraordinary life of a visionary hepatologist
Free

Albert Pares

doi: 10.1136/gutjnl-2017-313950

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January 13, 2018

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December 15, 2017

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October 30, 2017

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