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Research Article
The effect of intravenous prostaglandin F2 alpha and E2 on the motility of the sigmoid colon.
  1. R H Hunt,
  2. J B Dilawari,
  3. J J Misiewicz

    Abstract

    The effect of a 20-min intravenous infusion of prostaglandin E2 (0-08 mug kg-1 min-1) or of prostaglandin F2 alpha (0-8 mug kg-1 min-1) on the segmental pressures in the sigmoid colon was studied in 12 patients. Prostaglandin F2 alpha had no measurable effect, but prostaglandin E2 significantly inhibited sigmoid motility.

    https://doi.org/10.1136/gut.16.1.47

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