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Subcutaneous seeding of hepatocellular carcinoma after percutaneous needle biopsy
  1. S N SCHOTMAN
  1. R A DE MAN
  1. J STOKER
  1. P E ZONDERVAN
  1. J N M IJZERMANS
  1. Departments of General Surgery
  2. Department of Hepatogastroenterology
  3. Department of Radiology
  4. Department of Pathology
  5. Department of General Surgery
  6. Erasmus University Hospital Dijkzigt
  7. P.O. Box 2040, 3000 CA Rotterdam
  8. The Netherlands
  1. Dr IJzermans (email:IJzermans{at}hlkd.azr.nl).

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Background—In patients with a hepatic mass, malignancy can be diagnosed or excluded by a needle biopsy. However, this procedure can cause the formation of subcutaneous metastatic nodules in the needle tract. We present a case of recurrent subcutaneous seeding four years after a biopsy of a small hepatocellular carcinoma (HCC).

Case report—A 30 year old woman with hepatitis B liver cirrhosis presented with a raised serum α-fetoprotein (AFP) (271 μg/l; normal: <20 μg/l); ultrasound detected a liver mass. Additional spiral computed tomography showed a 2 cm diameter subcapsular mass in segment V. There were also two satellite lesions, measuring less than 1 cm in the same segment. To confirm the diagnosis of HCC, an ultrasound guided needle biopsy was performed using an 18 gauge Tru-cut needle and Biopty-gun. Two passes were needed to …

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