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I read with interest the paper by Attwood and colleagues (Gut 2003;52:181–5) on eosinophilic oesophagitis (EO). According to the authors, the distinct clinical syndrome of EO is not usually seen either as a component of gastro-oesophageal reflux disease or as a variant of eosinophilic gastroenteritis (EG).
The diagnostic hallmark of EO is odynophagia and the diagnosis is always histology dependent (>20 eosinophils/high power field) (Gut 2003;52:181–5). In the paediatric setting, the condition is widely recognised but the adult EO may escape diagnosis due to general lack of awareness of the condition. In this respect, the paper by Attwood and colleagues (Gut 2003;52:181–5) is a valuable contribution towards understanding the complex oesophageal condition of EO.
The pathophysiology of …