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Letter
Changing epidemiology of IPSID in Southern Iran
  1. K B Lankarani,
  2. S M Masoompour,
  3. M B Masoompour,
  4. R Malekzadeh,
  5. S Z Tabei,
  6. M Haghshenas
  1. Gastroenterology and Hepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran
  1. Correspondence to:
    Dr K B Lankarani
    Gastroenterology and Hepatology Research Center, Shiraz University of Medical Sciences, PO Box 71345-1414, Shiraz, Islamic Republic of Iran; Lankaransums.ac.ir

https://doi.org/10.1136/gut.2004.050526

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    Some 40 years ago physicians in the Middle East noted a high incidence and prevalence of upper small intestinal lymphoma.1–3 Later this condition was found to be associated with malabsorption as well as the presence of alpha heavy chain proteins.2–7 The disease was named by the WHO as “immunoproliferative small intestinal disease” (IPSID).6 One of the earliest reports of IPSID was from our centre.3,4 This study was designed to confirm the trend in the epidemiology of IPSID over the past 25 years in our medical centre. In a retrospective study (March 1974 to March 1999), we reviewed pathology reports from all surgical pathology laboratories in the province of Fars located in Southern Iran.

    All reports, which were labelled as IPSID, were reviewed by one …

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    Footnotes

    • Conflict of interest: None declared.