eLetters

299 e-Letters

  • Eosinophilic oesophagitis: treatment using Montelukast
    Ranjit Sinharay

    Dear Editor

    I read with interest the paper by Attwood et al.[1] on Eosinophilic oesophagitis (EO). According to the authors, the distinct clinical syndrome of EO is not usually seen either as a component of gastro- oesophageal reflux disease or as a variant of Eosinophilic gastroenteritis (EG).

    The diagnostic hallmark of EO is odynophagia and the diagnosis is always histology-dependent ( >20 eosino...

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  • Re: Is Hepatobiliary scintigraphy indeed insensitive for the diagnosis of sphincter of oddi dysfunct
    James Toouli

    Dear Editor

    I was very pleased to read the letter by Dr Laszlo Madacsy [1] in response to our article " Scintigraphy versus manometry in patients with suspected sphincter of Oddi dysfunction".[2]

    The major criticism of our study refers to the change from the original Sostre study [3] that we made with regards to administration of CCK-OP.I would like to refer the reader to our manuscript [2] for the explana...

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  • Long term follow-up of the helicobacter pylori induced gastric diffuse large B-cell MALT lymphoma fo
    Ranjit Sinharay

    Dear Editor

    I was interested to read the article by Alsolaiman et al. on the long term follow-up of gastric diffuse large B-cell lymphoma after eradication of Helicobacter pylori.[1]

    Gastric lymphomas represent about 5% of all gastric malignancies and are frequently due to MALT B-cell gastric lymphomas. Acquired MALT (Mucosa Associated Lymphoid Tissue) due to H. pylori infection provi...

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  • Is Hepatobiliary scintigraphy indeed insensitive for the diagnosis of sphincter of oddi dysfunction
    László Madácsy

    Dear Editor

    We read with interest the article by Craig et al. [1] who reported disappointing results on the value of quantitative hepatobiliary scintigraphy (QHBS) in patients with a suspected sphincter of Oddi dysfunction (SOD). Since our paper documenting contrary results was referred to,[2] we must add a few words of comment.

    First of all, it should be emphasized that in patients with SOD there is u...

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  • Diagnosing small bowel Crohn's disease with wireless capsule eneteroscopy
    Zvi Fireman

    Dear ,

    We thank Drs Schulman, Hollerbach and Schmiegel for their interest in our paper on the subject of diagnosing small bowel CD with wireless capsule endoscopy. Regarding colonoscopy.[1] Please note that in the Materials and Methods section under Study Population it is clearly stated that all of them underwent colonoscopies elsewhere at most six months prior to entering the study and this statement is rep...

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  • Initiation of treatment costs
    Thierry Poynard

    Dear Editor

    I read with a great interest the excellent cost effectiveness analysis of pegylated interferon alpha 2b and ribavirin combination in patients with chronic hepatitis C.[1] I was surprised by the relatively low cost of treatment initiation in Germany (Table 3). The cost estimate of pretherapeutic diagnostics at 473 Euros inclu...

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  • Worsening of steatosis and fibrosis progression in hepatitis C.
    Vlad D Ratziu

    Dear Editor

    We read with great interest the article by Laurent Castera and colleagues [1] and acknowledge the finding that worsening of steatosis in chronic hepatitis C, is associated with fibrosis progression. However, in our view the are no data supporting a casual role for this statistical association or any specific relation of this finding to chronic hepatitis C.

    First, the authors provide no expla...

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  • New imaging techniques, promise or passe
    Michael B Wallace MD, MPH

    Dear Editor

    I read with great interest, the article by Egger et al. [1] evaluating laser-induced fluorescence endoscopy (LIFE) and methylene blue (MB) directed biopsies for detection of dysplasia in Barrett's esophagus.

    As the authors point out, there have be no fully published studies to date on this much talked about procedure. The authors found that LIFE and MB had limited accuracy, as did standard...

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  • Predicting neoplastic lesions in the proximal colon: size does not matter that much
    Johann Hammer

    Dear Editor

    Gondal et al. must be congratulated for their study on the value of distal colonic lesions as predictors of lesions in the proximal colon. However, although their findings support previous studies on this subject,[1-3] their study design has deficiencies that have to be emphasized.

    While the study design allowed to report on the relation between proximal and distal colonic lesions in the pre...

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  • Atrophic gastritis: pathology and endoscopy in the reversibility assessment
    Massimo Rugge

    Dear Editor

    We read the manuscript published by MM Walker [1] with interest. We agree that histology remains the most suitable test for both detecting and assessing reversion of atrophic gastritis. Such a view elicits two basic questions, however, i.e.
    (a) how consistent are pathologists in recognizing gastric atrophy? and
    (b) in Walker’s words, “where to biopsy?” and, we might add,...

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