eLetters

299 e-Letters

  • Colon cancer after infliximab therapy for Crohn’s disease in a young liver transplant recipient
    Laurent Peyrin-Biroulet

    Dear Editor,

    In a recent issue of the Journal[1], Biancone et al. showed a comparable frequency of new diagnosis of neoplasia in inflammatory bowel disease (IBD) patients treated with infliximab and in patients who never received infliximab. These data seem to confirm reassuring message from clinical trials.[2,3] A peculiar situation may be IBD patients having had liver transplantation for primary sclerosing ch...

    Show More
  • Authors' reply: Small intestinal transplantation
    Stephen J Middleton

    Dear Editor,

    Dr Gupte and colleagues conclude that our article "does not acknowledge the contribution of the paediatric experience in this developing field" Nonetheless, the article does outline the development of small intestinal transplantation internationally for both adults and paediatrics and includes all of the paediatric outcome data submitted to the international registry, which we believe does include t...

    Show More
  • Liver fibrosis assessment by transient elastography in hepatitis C patients with normal ALT
    Ricardo Moreno-Otero

    Dear Editor,

    We read with interest the paper by Foucher et al.[1] where the authors assess the accuracy of transient elastography for the detection of cirrhosis. Its use to assessing the severity of chronic liver disease in other clinical scenarios warrant further evaluations. According to large population studies, the prevalence of chronically hepatitis C virus (HCV) infected patients who have persistently normal...

    Show More
  • Is this really the current status of small bowel transplantation in the UK?
    Girish L Gupte

    Dear Editor,

    We read with interest the article on ‘The current status of small bowel transplantation in the UK and internationally’ by Middleton et al.[1] This is a timely article about the improving worldwide outcome following small bowel transplantation, but does not fully reflect the status of small bowel transplantation in the UK. In the UK, the Department of Health through NSCAG (National Specialist Commissio...

    Show More
  • White cell scanning has a role in imaging small and large bowel
    Andrew P Poullis

    Dear Editor,

    I enjoyed the article by Albert et al. comparing newly emerging imaging modalities for the assessment and detection of small bowel Crohn’s disease, an area of the gastro-intestinal tract that is often difficult to adequately image, assess and biopsy.[1]

    However, their article failed to mention 99mTc HMPAO labelled white cell scanning at all as a method of imaging the small (and large) bowel...

    Show More
  • Dental erosion as extraoesophageal manifestation of gastro-oesophageal reflux
    Adolfo Benages

    Dear Editor,

    Dental erosion can be considered as an extraoesophageal manifestation of gastro-oesophageal reflux disease (GORD). Many reports have implicated refluxed gastric acid as a cause or contributory factor in the development of extraoesophageal disorders (“atypical” symptoms related to GORD), but the presence of lesions in oral cavity in patients with acid reflux has been less studied. The association between...

    Show More
  • The site distribution of gastrointestinal carcinoids differs between races
    Tsuyoshi Konishi

    Dear Editor,

    We read with great interest the guideline for gastroenteropancreatic neuroendocrine (including carcinoid) tumors by Ramage et al.[1] In this excellent guideline, they reported that appendix is the most frequent site of gastrointestinal primary endocrine tumors, consisting 35% of the total tumors, while colon and rectal carcinoids consisted only 7% and 10%, respectively. One important aspect not ment...

    Show More
  • ASCAs in (auto-) immune small bowel diseases
    Zsolt Barta, M.D.Ph.D.

    Dear Editor,

    We read with interest the article by Israeli et al. on Anti- Saccharomyces cerevisiae and antineutrophil cytoplasmic antibodies as predictors of inflammatory bowel disease as they concluded that ASCA and pANCA may predict development of inflammatory bowel disease years before the disease is clinically diagnosed.[1]

    Anti-Saccharomyces cerevisiae antibodies (ASCA) are known as specific markers i...

    Show More
  • Authors' reply
    Antonius Schneider

    Dear Editor,

    Re: Stratification by gender and subgroup is necessary for RCT on IBS by Prof. Bian

    Thank you for the communication of your interesting study results. Your findings highlight a problem especially for acupuncture research. Many experimental trials are pointing out the efficacy of acupuncture, also regarding problems of the gastrointestinal tract.[1-4] However, many of these trials are not a...

    Show More
  • Association of preneoplastic gastric lesions and H. pylori
    Shamsul A Bhuiyan,MD

    Dear Editor,

    In 1994, Helicobacter pylori was declared a type 1 carcinogen—a definite cause of human cancer—by the International Agency for Research on Cancer (IARC).[1]

    We read with interest the study by Mera et al.[1] on the effect of eradicating H. pylori infection on precancerous gastric lesions. Here the author Mera et al conclude that “Preneoplastic gastric lesions regress at a rate equal to the squ...

    Show More

Pages