eLetters

299 e-Letters

  • A bacterial aetiology of pouchitis
    Martijn P Gosselink

    Dear Editor

    We read with interest the paper by Bell and co-workers.[1] They conducted a study in order to evaluate the effect of the pouch flora on the proliferation of lymphocytes. They observed that a pouchitis derived bacterial sonicate resulted in a significantly higher proliferation of the lymphocytes obtained from healthy pouch patients’ than a non-pouchitis derived sonicate. The capacity to induce this prol...

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  • Crohn’s ileitis after liver transplantation from a living-related donor with Crohn’s disease
    Konstantinos A. Papadakis

    Dear Editor

    We read with interest the case described recently by Sonwalkar et al, of a patient who developed fulminant Crohn’s colitis after allogeneic stem cell transplantation (ASCT).[1] Although the donor had no known Crohn’s disease (CD) and did not carry the IBD3 or IBD5 haplotypes associated with CD, HLA class III mismatches at IBD3 and a CD-associated polymorphism of the 5'UTR of NOD2/CARD15 were presen...

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  • PAIR-derived US-guided techniques for the treatment of cystic echinococcosis: a Chinese experience
    Dominique A. Vuitton

    Dear Editor

    For decades, surgical operation has been considered as the only ideal therapeutic method in the treatment of hydatid cyst/cystic echinococcosis, a parasitic zoonosis that still remains prevalent in a number of countries, and especially PR China where the estimated number of cases is over 500,000.[1] The ultrasound (US)-guided Puncture-Aspiration-Injection -Reaspiration (PAIR) technique [2,3] has now ga...

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  • Author's reply
    Nicholas J. Shaheen

    Dear Editor

    We thank Hur for his interest in our article.[1] We agree that his article,[2] which appeared after the initial iterations of our article[3] had been written, but prior to the acceptance of our revised manuscript, is highly pertinent to our work, as it models the same clinical scenario.

    There are clearly some differences in the models, which are likely due in part to the estimates used to...

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  • Author's reply
    Terumi Kamisawa

    Dear Editor

    We thank Dr Taniguchi et al. for his interesting presentation of interstitial pneumonia associated with autoimmune pancreatitis (AIP).

    We have experienced 24 cases of AIP, however, no cases showed interstitial pneumonia clinically. Recently we immunohistochemically examined the organs of eight patients with AIP using anti-IgG4 antibody. Many IgG4-positive plasmacytic infiltration was dete...

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  • Diagnotic endoscopy: does it help?
    Richard G Fiddian-Green

    Dear Editor

    Having questioned the value of therapeutic endoscopy let me question the value of diagnostic endoscopy having lived through the days from when it was not available to its current status. Having given the matter considerable thought[1] I seriously doubt that it has been of any value. It might even have had an adverse effect on outcome but delaying operative intervention in those who need it and amongst wh...

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  • Deranged smooth muscle a-actin as a biomarker of intestinal pseudo-obstruction
    Adrian C Bateman
    Dear Editor

    We read with interest the article by Knowles and colleagues[1] in which the authors conclude that immunostaining of the adult jejunum with smooth muscle a-actin (ASMA) may be a valuable biomarker of chronic idiopathic intestinal pseudo-obstruction (CIIP). We recently published a similar study[2] in which 17 archival formalin fixed and paraffin wax embedded samples of small intestine and 12 samples of large...

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  • Colon cancer after infliximab therapy for Crohn’s disease in a young liver transplant recipient
    Laurent Peyrin-Biroulet

    Dear Editor,

    In a recent issue of the Journal[1], Biancone et al. showed a comparable frequency of new diagnosis of neoplasia in inflammatory bowel disease (IBD) patients treated with infliximab and in patients who never received infliximab. These data seem to confirm reassuring message from clinical trials.[2,3] A peculiar situation may be IBD patients having had liver transplantation for primary sclerosing ch...

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  • Remarkable difference in the mode of HCV transmission among haemodialysis patients and IVDAs
    Seyed M Alavian

    Dear Editor

    We read with great interest the letter by Saxena et al.[1]

    We would however take issue with their hypothesis, as we indeed believe in the remarkable differences in the HCV transmission mode in these two high-risk groups. The studies have reported 70-90 percent as the HCV infection prevalence rate among intravenous drug abusers (IVDAs).[2] The main source of HCV infection in this populat...

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  • Guidelines for the diagnosis and treatment of cholangiocarcinoma
    Tony CK Tham

    Dear Editor

    We read with interest the British Society of Gastroenterology guidelines for the diagnosis and treatment of cholangiocarcinoma (Gut 2002:51(Suppl VI): 1-9).

    The authors recommend that routine biliary drainage before assessing resectability or preoperatively should be avoided except in the context of acute cholangitis. They do not state the rationale for this approach. Presumably the a...

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