PT - JOURNAL ARTICLE AU - Evans, D. J. AU - Pollock, D. J. TI - In-situ and invasive carcinoma of the colon in patients with ulcerative colitis AID - 10.1136/gut.13.7.566 DP - 1972 Jul 01 TA - Gut PG - 566--570 VI - 13 IP - 7 4099 - http://gut.bmj.com/content/13/7/566.short 4100 - http://gut.bmj.com/content/13/7/566.full SO - Gut1972 Jul 01; 13 AB - Four cases are described in which ulcerative colitis was complicated by carcinoma and in which the extent of the accompanying in-situ carcinoma (precancer) was determined. The extent of the in-situ carcinoma was very variable and in all cases the rectum was spared in whole or part. Search for in-situ carcinoma in rectal biopsies will fail to indicate the development of malignancy in some patients with ulcerative colitis. Alternative methods of cancer detection in this group are discussed.