PT - JOURNAL ARTICLE AU - C. A. Loehry AU - A. T. R. Axon AU - P. J. Hilton AU - R. C. Hider AU - B. Creamer TI - Permeability of the small intestine to substances of different molecular weight AID - 10.1136/gut.11.6.466 DP - 1970 Jun 01 TA - Gut PG - 466--470 VI - 11 IP - 6 4099 - http://gut.bmj.com/content/11/6/466.short 4100 - http://gut.bmj.com/content/11/6/466.full SO - Gut1970 Jun 01; 11 AB - The permeability of the rabbit small intestine has been studied by measuring the plasma clearances of water-soluble molecules over the molecular weight range 60-33,000. An inverse relationship has been demonstrated between permeability and molecular weight. The significance of these findings in relation to current concepts of the `pore hypotheses' is discussed, and the possible physiological and pathological implications are considered.