RT Journal Article
SR Electronic
T1 Permeability of the small intestine to substances of different molecular weight
JF Gut
JO Gut
FD BMJ Publishing Group Ltd and British Society of Gastroenterology
SP 466
OP 470
DO 10.1136/gut.11.6.466
VO 11
IS 6
A1 C. A. Loehry
A1 A. T. R. Axon
A1 P. J. Hilton
A1 R. C. Hider
A1 B. Creamer
YR 1970
UL http://gut.bmj.com/content/11/6/466.abstract
AB The permeability of the rabbit small intestine has been studied by measuring the plasma clearances of water-soluble molecules over the molecular weight range 60-33,000. An inverse relationship has been demonstrated between permeability and molecular weight. The significance of these findings in relation to current concepts of the `pore hypotheses' is discussed, and the possible physiological and pathological implications are considered.