RT Journal Article SR Electronic T1 The surgical significance of methaemalbuminaemia JF Gut JO Gut FD BMJ Publishing Group Ltd and British Society of Gastroenterology SP 995 OP 1000 DO 10.1136/gut.12.12.995 VO 12 IS 12 A1 Battersby, Cameron A1 Green, Marjorie K. YR 1971 UL http://gut.bmj.com/content/12/12/995.abstract AB A quantitative estimation of plasma methaemalbumin can be useful. In pancreatitis, it usually indicates severe and haemorrhagic disease, and is thus of prognostic importance, as well as indicating the need for the full therapeutic regime for conservative management of the disease. It may be helpful diagnostically in some patients with pancreatitis in whom it remains elevated after the serum amylase has returned to normal. Raised levels may indicate laparotomy in patients in whom the diagnosis of pancreatitis is considered but who are not responding to conservative measures. Such patients may occasionally be suffering from intestinal infarction or other surgically remediable condition. However, it has been found that the level of methaemalbumin in the plasma may be raised above the upper limit of the normal range of 5ยท5 mg% in occasional cases of gastrointestinal bleeding and soft tissue trauma and is not always raised in haemorrhagic pancreatitis.