PT  - JOURNAL ARTICLE
AU  - S P Wilkinson
AU  - V A Arroyo
AU  - H Moodie
AU  - L M Blendis
AU  - R Williams
TI  - Abnormalities of sodium excretion and other disorders of renal function in fulminant hepatic failure.
AID  - 10.1136/gut.17.7.501
DP  - 1976 Jul 01
TA  - Gut
PG  - 501--505
VI  - 17
IP  - 7
4099  - http://gut.bmj.com/content/17/7/501.short
4100  - http://gut.bmj.com/content/17/7/501.full
SO  - Gut1976 Jul 01; 17
AB  - Renal function was evaluated in 40 patients with fulminant hepatic failure, They were divided into two groups on the basis of glomerular filtration rates greater than 40 ml/min or less than 25 ml/min. A number of patients in group 1 had markedly abnormal renal retention of sodium together with a reduced free water clearance and low potassium excretion which could be explained by increased proximal tubular reabsorption of sodium. The patients in group 2 had evidence that renal tubular integrity was maintained when the glomerular filtration rate was greater than or equal ml/min (functional renal failure), but evidence of tubular damage was present when this was less than 3 ml/min (acute tubular necrosis).