PT  - JOURNAL ARTICLE
AU  - Compston, J E
AU  - Creamer, B
TI  - Plasma levels and intestinal absorption of 25-hydroxyvitamin D in patients with small bowel resection.
AID  - 10.1136/gut.18.3.171
DP  - 1977 Mar 01
TA  - Gut
PG  - 171--175
VI  - 18
IP  - 3
4099  - http://gut.bmj.com/content/18/3/171.short
4100  - http://gut.bmj.com/content/18/3/171.full
SO  - Gut1977 Mar 01; 18
AB  - Plasma levels of 25-hydroxyvitamin D (25-OHD) were found to be significantly reduced in a group of patients with small bowel resection when compared with normal controls. Plasma levels of 25-OHD after an oral dose of 25-hydroxyvitamin D3 (25-ohd3) were also reduced in the patient group. Dietary intake of vitamin D tended to be low in many patients, but seasonal variation of plasma 25-OHD levels indicated normal exposure to sunlight in most of the patients studied. It is suggested that these studies provide some evidence for malabsorption of 25-OHD after small bowel resection, which, it is postulated, may be due to interruption of the enterohepatic circulation of bile acids and of 25-OHD. These factors may contribute towards the low plasma levels of 25-OHD found in the patient group.