PT - JOURNAL ARTICLE AU - Hamilton, S G AU - Sheiner, H J AU - Quinlan, M F TI - Continuous monitoring of the effect of pentagastrin on gastric emptying of solid food in man. AID - 10.1136/gut.17.4.273 DP - 1976 Apr 01 TA - Gut PG - 273--279 VI - 17 IP - 4 4099 - http://gut.bmj.com/content/17/4/273.short 4100 - http://gut.bmj.com/content/17/4/273.full SO - Gut1976 Apr 01; 17 AB - By continuous monitoring of a solid meal labelled with a radiopharmaceutical it has been possible to determine the effects of drugs on gastric emptying and motility during a single study. Predictably hyoscine delayed, and bethanechol increased, the rate of gastric emptying. Pentagastrin initially produced marked antral activity resulting in a physiological stricture and subsequent delay in the overall rate of gastric emptying. Fundal motility was unaffected though reflux from the antrum occurred.