RT Journal Article
SR Electronic
T1 Association of HLA-A3 and HLA-B14 antigens with idiopathic haemochromatosis.
JF Gut
JO Gut
FD BMJ Publishing Group Ltd and British Society of Gastroenterology
SP 332
OP 334
DO 10.1136/gut.17.5.332
VO 17
IS 5
A1 M Simon
A1 M Bourel
A1 R Fauchet
A1 B Genetet
YR 1976
UL http://gut.bmj.com/content/17/5/332.abstract
AB The frequency of HLA-A3 and HLA-B14 antigens was significantly higher in a series of 51 patients with idiopathic haemochromatosis than in a control group, being respectively 78-4 versus 27-0% and 25-5 versus 3-4%. This finding strongly supports the suggestion that idiopathic haemochromatosis is a genetic disease and suggests that the gene(s) responsible for the disease may be linked to the histocompatibility genes.