TY - JOUR T1 - Effects of fasting on the composition of gallbladder bile. JF - Gut JO - Gut SP - 1087 LP - 1089 DO - 10.1136/gut.21.12.1087 VL - 21 IS - 12 AU - H M Bloch AU - J R Thornton AU - K W Heaton Y1 - 1980/12/01 UR - http://gut.bmj.com/content/21/12/1087.abstract N2 - Gallbladder bile was aspirated from the duodenum in nine healthy women after three separate periods of fasting after a standardised meal. Mean cholesterol saturation index was significantly greater after a 15 hour fast (1.35 +/- 0.08) than after a 10 hour fast (1.05 +/- 0.10). However, after 20 hours of fasting, mean cholesterol saturation index had fallen to 1.13 +/- 0.10. Total biliary lipid concentration was unaffected. These findings suggest that fasting has a series of effects on gallbladder bile and that bile sampling should be carried out at at standardised period of time after the last meal. ER -